دورية أكاديمية
أعرض في EDS

Is type III prostatitis also associated with bacterial infection?

التفاصيل البيبلوغرافية
العنوان: Is type III prostatitis also associated with bacterial infection?
المؤلفون: Song WJ; Department of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.; Sexual Health Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China., Gao J; Department of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.; Sexual Health Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China., Huang JW; Department of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.; Sexual Health Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China., Liu Y; Department of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.; Sexual Health Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China., Long Z; Department of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.; Sexual Health Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China., He LY; Department of Urology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.; Sexual Health Research Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
المصدر: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Jul 03; Vol. 13, pp. 1189081. Date of Electronic Publication: 2023 Jul 03 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Lausanne : Frontiers Media SA
مواضيع طبية MeSH: Prostatitis*/complications , Prostatitis*/diagnosis , Bacterial Infections*/complications , Bacterial Infections*/microbiology, Male ; Humans ; RNA, Ribosomal, 16S/genetics ; Chronic Disease ; Bacteria/genetics
مستخلص: Objective: To explore whether type III prostatitis is related to bacterial infection by detecting the composition and function of microorganisms in expressed prostatic secretion (EPS) of patients with chronic prostatitis (CP) and healthy people.
Methods: According to the inclusion and exclusion criteria, 57 subjects were included in our study, divided into the healthy group, type II prostatitis group, and type III prostatitis group. 16s rRNA sequencing technique was used to detect and analyze the microbial composition of EPS in each group. Additionally, the metagenomics sequencing technique was used to further explore the function of different bacteria in the type III prostatitis group. Data analysis was performed by bioinformatics software, and the results were statistically significant when P<0.05.
Results: Many microorganisms exist in EPS in both CP patients and healthy populations. However, the relative abundance of Pseudomonas , Haemophilus , Sneathia , Allobaculum , and Enterococcus in CP patients (including type II and III) were significantly different. Still, the relative abundance of different bacteria in type II prostatitis patients was much higher than in type III. The metagenomics sequencing results for the type III prostatitis group showed that the different bacteria had certain biological functions.
Conclusion: Based on our sequencing results and previous studies, we suggest that type III prostatitis may also be caused by bacterial infection.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2023 Song, Gao, Huang, Liu, Long and He.)
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فهرسة مساهمة: Keywords: 16s rRNA sequencing technique; chronic prostatitis; expressed prostatic secretion; metagenomics; microbiology
المشرفين على المادة: 0 (RNA, Ribosomal, 16S)
تواريخ الأحداث: Date Created: 20230719 Date Completed: 20230721 Latest Revision: 20230721
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10351278
DOI: 10.3389/fcimb.2023.1189081
PMID: 37465760
قاعدة البيانات: MEDLINE
الوصف
تدمد:2235-2988
DOI:10.3389/fcimb.2023.1189081