دورية أكاديمية
Delineating and sparing the ileal conduit in adjuvant radiotherapy for bladder cancer with modulated radiotherapy.
| العنوان: | Delineating and sparing the ileal conduit in adjuvant radiotherapy for bladder cancer with modulated radiotherapy. |
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| المؤلفون: | Goyal S; Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Vias P; Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Periasamy K; Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Madan R; Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Trivedi G; Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Devana SK; Department of Urology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Prashar H; Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Khosla D; Department of Radiotherapy and Oncology, Post Graduate Institute of Medical Education and Research, Chandigarh, India. |
| المصدر: | Journal of cancer research and therapeutics [J Cancer Res Ther] 2023 Apr-Jun; Vol. 19 (3), pp. 731-737. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medknow Publications Country of Publication: India NLM ID: 101249598 Publication Model: Print Cited Medium: Internet ISSN: 1998-4138 (Electronic) Linking ISSN: 19984138 NLM ISO Abbreviation: J Cancer Res Ther Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Mumbai, India : Medknow Publications |
| مواضيع طبية MeSH: | Radiotherapy, Intensity-Modulated*/methods , Urinary Diversion* , Urinary Bladder Neoplasms*/radiotherapy , Urinary Bladder Neoplasms*/surgery, Humans ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted/methods ; Radiotherapy, Adjuvant ; Prospective Studies ; Organs at Risk/radiation effects |
| مستخلص: | Purpose: We undertook a prospective planning study to describe the delineation of ileal conduit (IC) loop on radiotherapy planning computed tomography (RTP CT) scan as an organ at risk (OAR) and its sparing using volumetric modulated arc therapy (VMAT) during adjuvant irradiation of bladder malignancies. Materials and Methods: Fifteen patients with bladder malignancy needing adjuvant radiotherapy postoperatively and having normal renal function underwent delayed phase RTP CT from June 2020 to March 2021, with certain modifications (Foley's catheter through stoma, additional delayed scans). We identified the course of ureters, external stoma, IC, and uretero-ileal (right and left) anastomotic sites. VMAT plans were generated. Results: A step-by-step description is given. Genitourinary OARs include kidneys, ureters, uretero-ileal anastomoses, and IC. The contrast on delayed scan opacifies ureters and IC. IC can be seen three-dimensionally as a structure with two fixed ends (blind proximal end anterior to the right sacroiliac joint and the open distal end over the right anterior abdominal wall in parasagittal location) and a 15-20 cm hanging intraabdominal loop that lies adjacent to the right iliac vessels. For prescription doses (PD) of 50.4 gray and 54 gray, respectively, VMAT plan achieved IC dose maximum to less than PD and V Conclusions: Delineation of IC as an OAR is feasible with slight modifications in the RTP protocols. VMAT (or other forms of intensity modulated radiation therapy) can help IC sparing and should be considered when it lies in close proximity to target volumes and the risk of additional morbidity is considerable. |
| فهرسة مساهمة: | Keywords: Cystectomy; intensity modulated; organs at risk; radiotherapy; urinary bladder neoplasms; urinary diversion |
| تواريخ الأحداث: | Date Created: 20230720 Date Completed: 20231102 Latest Revision: 20231102 |
| رمز التحديث: | 20231102 |
| DOI: | 10.4103/jcrt.jcrt_1843_21 |
| PMID: | 37470602 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1998-4138 |
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| DOI: | 10.4103/jcrt.jcrt_1843_21 |