دورية أكاديمية
أعرض في EDS

Histological Study on the Thickness of Gray Matter at the Summit and Bottom of Folium in Different Age Groups of Bangladeshi People.

التفاصيل البيبلوغرافية
العنوان: Histological Study on the Thickness of Gray Matter at the Summit and Bottom of Folium in Different Age Groups of Bangladeshi People.
المؤلفون: Nitu NS; Anatomy, Khulna City Medical College, Khulna, BGD., Sultana SZ; Anatomy, Mymensingh Medical College, Mymensingh, BGD., Haq A; Statistics, Gonoshasthaya-RNA Molecular Diagnostic and Research Center, Dhanmondi, BGD., Sumi SA; Anatomy, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, BGD., Bose SK; Anatomy, Gonoshasthaya Samaj Vittik Medical College, Savar, BGD., Sinha S; Physiology, Khulna City Medical College and Hospital, Khulna, BGD., Kumar S; Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND., Haque M; Karnavati Scientific Research Center (KSRC), School of Dentistry, Karnavati University, Gandhinagar, IND.; Pharmacology and Therapeutics, National Defence University of Malaysia, Kuala Lumpur, MYS.
المصدر: Cureus [Cureus] 2023 Jul 18; Vol. 15 (7), pp. e42103. Date of Electronic Publication: 2023 Jul 18 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Context The cerebellum is a part of the hindbrain and consists of cortical gray matter (GM) at the surface and a medullary core of white matter (WM). The GM contains a cell body of neurons that helps process and transmit any command type through nerve fibers found in the WM. The main functions of GM in the central nervous system empower persons to control motor activity, recollection, and passion. So, this research aims to assess the thickness of GM at the summit and bottom of folia by histologically studying the cerebellum cortex. Methods The collection of data was a descriptive type of cross-sectional study. The method was the purposive type. This study was conducted from August 2016 to March 2017, and the research was carried out at Mymensingh Medical College's Department of Anatomy, Bangladesh. Specimens containing cerebellum were preserved from Bangladeshi cadavers according to sexes and ages ranging in years. We chose fresh specimens from people who died within the last 12 hours and preserved them in 10% formol saline. The size of the tissue that was collected for the histological study was not more than 2 cm 2 and not more than 4-5 mm thick. Then the tissue was placed in 10% formol saline. This fluid was used for quick fixation and partial dehydration of the tissue. After dehydration, each tissue segment is processed for infiltration and embedding separately. Every section was stained with hematoxylin and eosin stain (H&E) before being coated with dibutyl phthalate polystyrene xylene (DPX) coverslips on slides. Result The mean (±SD) thickness of GM at the summit of folium was 886.2±29.7µm in Group A, 925.2±25.9µm in Group B, 912.7±22.3µm in Group C, and 839.9±40.7µm in Group D. Mean (±SD) GM thickness at the bottom of the fissure was 395.6±12.2 µm, 403.9±26.0µm, 380.4±23.4 µm, and 375.8±28.8 µm in Groups A, B, C, and D respectively. Conclusion The thickness of the cortex is an essential factor in the normal development process, and it was similar in the current study. Normal aging, Alzheimer's disease, and other dementias cause reduced GM which makes the cortical sheet thin. Huntington's disease, corticobasal degeneration, amyotrophic lateral sclerosis, and schizophrenia are all examples of neurological disorders. Cortical thinning is typically locally localized, and the progression of atrophy can thus disclose much about a disease's history and causal variables. The present study correspondingly found that GM was reduced after the age of 50 years onward. Furthermore, longitudinal investigations of cortical atrophy have the potential to be extremely useful in measuring the efficacy of a wide range of treatments.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2023, Nitu et al.)
References: AJNR Am J Neuroradiol. 2019 Sep;40(9):1464-1468. (PMID: 31467235)
Intelligence. 2013 Sep;41(5):597-606. (PMID: 24744452)
Front Aging Neurosci. 2021 Feb 03;13:593898. (PMID: 33613265)
J Alzheimers Dis. 2023;91(3):1059-1071. (PMID: 36565111)
Clin Park Relat Disord. 2019 Aug 30;1:66-71. (PMID: 34316603)
Front Hum Neurosci. 2018 May 01;12:168. (PMID: 29765312)
Sci Rep. 2016 Oct 27;6:36151. (PMID: 27786306)
Diagnostics (Basel). 2021 Mar 23;11(3):. (PMID: 33807060)
Psychiatry Res. 2013 Nov 30;214(2):109-15. (PMID: 24041490)
Front Hum Neurosci. 2018 Aug 14;12:301. (PMID: 30154704)
Neuroscience. 2013 Oct 22;251:21-32. (PMID: 23069756)
Nat Rev Neurosci. 2015 Feb;16(2):79-93. (PMID: 25601779)
J Psychiatry Neurosci. 2018 Mar;43(2):120-130. (PMID: 29481319)
Front Psychiatry. 2021 Jul 01;12:671348. (PMID: 34276443)
Int J Obes (Lond). 2018 Mar;42(3):455-461. (PMID: 28993708)
Methods Mol Biol. 2020;2092:65-75. (PMID: 31786782)
Neuropsychologia. 2018 Jun;114:19-31. (PMID: 29654881)
Brain. 2007 Apr;130(Pt 4):1159-66. (PMID: 17353226)
J Forensic Odontostomatol. 2015 Jul 01;33(1):19-26. (PMID: 26851446)
Brain Topogr. 2019 Jan;32(1):142-160. (PMID: 30206799)
Res Dev Disabil. 2016 Aug;55:218-25. (PMID: 27214680)
Cerebellum. 2017 Feb;16(1):203-229. (PMID: 26873754)
Neurosci Biobehav Rev. 2015 Dec;59:53-63. (PMID: 25825285)
Cureus. 2019 Sep 9;11(9):e5601. (PMID: 31700714)
Sci Rep. 2021 Mar 23;11(1):6078. (PMID: 33758256)
Neurochem Res. 2020 Feb;45(2):354-370. (PMID: 31786717)
Prog Neuropsychopharmacol Biol Psychiatry. 2022 Jul 13;117:110540. (PMID: 35240226)
Cereb Cortex. 2016 Aug;26(8):3370-3378. (PMID: 26209848)
JAMA Psychiatry. 2016 Jan;73(1):64-72. (PMID: 26650724)
Turk J Emerg Med. 2023 Mar 02;23(2):104-110. (PMID: 37169030)
Front Neurol. 2018 Jul 30;9:614. (PMID: 30104996)
Dev Med Child Neurol. 2015 Dec;57(12):1159-67. (PMID: 25970144)
J Neural Transm (Vienna). 2018 Apr;125(4):615-650. (PMID: 29222591)
Neurobiol Aging. 2012 Mar;33(3):617.e1-9. (PMID: 20739099)
Cereb Cortex. 2007 Jul;17(7):1550-60. (PMID: 16945978)
Neuropsychobiology. 2022;81(4):257-264. (PMID: 35158360)
Neuroimage. 2010 Jul 1;51(3):943-51. (PMID: 20211265)
Schizophrenia (Heidelb). 2023 Apr 29;9(1):27. (PMID: 37120642)
J Neurol Sci. 2019 Mar 15;398:31-38. (PMID: 30682518)
Handb Clin Neurol. 2018;154:181-202. (PMID: 29903439)
Behav Brain Funct. 2022 Apr 28;18(1):6. (PMID: 35484543)
Mult Scler. 2019 Mar;25(3):382-391. (PMID: 29320933)
Radiology. 2023 Apr;307(2):e220989. (PMID: 36648348)
Pediatr Res. 2019 Sep;86(3):365-374. (PMID: 31212303)
Front Neurol. 2022 Sep 07;13:922199. (PMID: 36158963)
Neuron. 2014 Aug 6;83(3):518-32. (PMID: 25102558)
Am J Geriatr Psychiatry. 2013 Feb;21(2):184-95. (PMID: 23343492)
Aging Dis. 2017 Dec 1;8(6):899-909. (PMID: 29344423)
Neuroscience. 2013 Oct 22;251:90-107. (PMID: 22546337)
Neurobiol Aging. 2014 Jan;35(1):240-6. (PMID: 23992619)
Eur J Nucl Med Mol Imaging. 2019 May;46(5):1111-1116. (PMID: 30627816)
Front Neural Circuits. 2013 Jan 10;6:116. (PMID: 23335884)
Sci Rep. 2023 Jan 20;13(1):1172. (PMID: 36670149)
Mech Ageing Dev. 2021 Dec;200:111575. (PMID: 34600936)
Nat Rev Neurosci. 2019 May;20(5):298-313. (PMID: 30923348)
World Neurosurg. 2017 Mar;99:695-700.e1. (PMID: 28063896)
Neurology. 2023 Jul 18;101(3):e289-e299. (PMID: 37268436)
Clujul Med. 2018;91(2):176-180. (PMID: 29785155)
Cereb Cortex. 2007 Sep;17(9):2163-71. (PMID: 17118969)
IEEE/ACM Trans Comput Biol Bioinform. 2018 Mar-Apr;15(2):570-580. (PMID: 29610105)
Front Mech Eng. 2021 Jul;7:. (PMID: 35465618)
PLoS One. 2019 Dec 23;14(12):e0226525. (PMID: 31869402)
Mult Scler. 2019 Feb;25(2):204-216. (PMID: 29173009)
Aust N Z J Psychiatry. 2020 Jun;54(6):633-643. (PMID: 31696728)
Brain Res. 2020 Aug 1;1740:146847. (PMID: 32330518)
Elife. 2018 Sep 20;7:. (PMID: 30226467)
Neuroimage. 2017 Apr 15;150:358-372. (PMID: 27663988)
Neuroimage Clin. 2020;28:102374. (PMID: 32805678)
Neuropsychiatr Dis Treat. 2019 Apr 12;15:935-946. (PMID: 31114205)
J Neurol. 2022 Jun;269(6):2862-2873. (PMID: 35013788)
Front Neurol. 2020 Dec 23;11:593490. (PMID: 33424746)
Sleep. 2014 Jan 01;37(1):167-75. (PMID: 24470705)
Cerebellum. 2014 Feb;13(1):151-77. (PMID: 23996631)
فهرسة مساهمة: Keywords: breadth; cerebellum; examining; greyish nervous tissue; microscopic; organs; research; sectioning; staining; tissues
تواريخ الأحداث: Date Created: 20230721 Latest Revision: 20230722
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10354462
DOI: 10.7759/cureus.42103
PMID: 37476298
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.42103