دورية أكاديمية
أعرض في EDS

Exploring the Prevalence and Factors Influencing Clinical Trial Awareness in US Adults with Self-Reported Depression and Anxiety.

التفاصيل البيبلوغرافية
العنوان: Exploring the Prevalence and Factors Influencing Clinical Trial Awareness in US Adults with Self-Reported Depression and Anxiety.
المؤلفون: Sanusi IA; Internal Medicine, University of Texas at Houston, Houston, USA., Arisoyin AE; Internal Medicine, College of Medicine, University of Lagos, Lagos, NGA., Aruoture S; Psychiatry, Behavioral Hospital Of Bellaire, Houston, USA., Folorunsho IL; Emergency Department, Bader Al Janoub General Hospital, Najran, SAU., Okereke OP; Family Medicine, Ebonyi Sate University, Ebonyi, NGA., Adeyemo DA; Research, Texas A&M University, Corpus Christi, USA., Salawu MA; Medicine and Surgery, University of Ilorin College of Health Sciences, Ilorin, NGA.; Internal Medicine and Psychiatry, Houston Health Department, Houston, USA., Okobi OE; Family Medicine, Medficient Health Systems, Laurel, USA.; Family Medicine, Lakeside Medical Center, Belle Glade, USA., Gupta A; Internal Medicine, Spartan Health Sciences University, Vieux Fort, LCA., Akunne HS; Psychiatry, Delta State University, Abraka, NGA., Patel R; Psychiatry and Behavioral Sciences, Avalon University School of Medicine, Willemstad, CUW., Emmanuel O; Health Information Management, Emory Healthcare, Georgia, USA., Ezeudemba NC; Infectious Disease, Medical University of Silesia, Katowice, POL.
المصدر: Cureus [Cureus] 2023 Jun 22; Vol. 15 (6), pp. e40780. Date of Electronic Publication: 2023 Jun 22 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Objective: Lack of clinical trial awareness is a crucial barrier to clinical trial enrollment. The objective of this study was to examine the prevalence and factors associated with clinical trial awareness among US adults with self-reported depression and anxiety.
Methods: Data were collected from 896 adults who self-reported depression and anxiety from the 2020 Health Information National Trends Survey. Multinomial logistic regression was utilized to assess predictors of clinical trial awareness, particularly socio-demographic, health-related, and technological variables. Odds ratios (OR) for the associations were reported.
Results: About 60.4% of adults with self-reported depression or anxiety reported being aware of clinical trials. In the multivariable regression, education level, health-related social media use, and having access to a regular provider were all significantly associated with greater odds of clinical trial awareness among individuals with depression and/or anxiety. Specifically, individuals with at least some college education (OR 2.07, 95% confidence interval (CI); 1.28-3.34; p ​= ​0.004) were more likely to report awareness of clinical trials than those with less than a college education. Similarly, compared to those without access to health providers, individuals with depression and/or anxiety who had a regular provider had greater odds of clinical trial awareness (OR 2.23, 95% CI; 1.16-4.31; p ​= ​0.017). Additionally, those who reported two or more health-related uses of social media were significantly more likely to report clinical trial awareness than their counterparts who reported no health-related social media use (OR 3.17, 95% CI; 1.48-6.80; p ​= ​0.004).
Conclusion: Our study shows that about six in 10 adults with depression and anxiety in the United States were aware of clinical trials. However, some sub-groups of patients, particularly those without access to a regular health provider, those with a lower education level, and those with limited use of social media for health purposes, remain inadequately informed and may lack awareness of available clinical trials. These findings are crucial and identify subgroups of people with mental disorders that may benefit from targeted interventions to improve clinical trial awareness.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2023, Sanusi et al.)
References: J Cancer Educ. 2009;24(1):49-57. (PMID: 19259866)
Psychiatr Serv. 2009 Nov;60(11):1466-7. (PMID: 19880463)
J Health Commun. 2017 May;22(5):373-385. (PMID: 28339327)
J Natl Med Assoc. 2008 Feb;100(2):178-87. (PMID: 18300535)
J Affect Disord. 2021 May 1;286:296-300. (PMID: 33756307)
J Community Health. 2012 Apr;37(2):335-43. (PMID: 21805372)
MMWR Morb Mortal Wkly Rep. 2021 Oct 08;70(40):1427-1432. (PMID: 34618798)
Int J Environ Res Public Health. 2020 Sep 19;17(18):. (PMID: 32961766)
JAMA. 2004 Jun 9;291(22):2720-6. (PMID: 15187053)
JAMA Netw Open. 2022 Jun 1;5(6):e2217223. (PMID: 35704316)
J Educ Health Promot. 2020 May 28;9:124. (PMID: 32642480)
Cancer Nurs. 2011 Sep-Oct;34(5):E13-9. (PMID: 21252642)
MMWR Morb Mortal Wkly Rep. 2021 Apr 02;70(13):490-494. (PMID: 33793459)
Clin Ther. 2017 Nov;39(11):2203-2213. (PMID: 29079388)
Compr Psychiatry. 2020 Nov;103:152197. (PMID: 32992073)
BMJ. 2015 Jun 12;350:h3140. (PMID: 26071322)
Psychiatry Res. 2021 Oct;304:114120. (PMID: 34303946)
J Psychiatr Res. 2015 Nov;70:28-32. (PMID: 26424420)
Clin Trials. 2015 Jun;12(3):215-23. (PMID: 25673636)
Ethn Health. 2010 Jun;15(3):223-36. (PMID: 20336563)
Am Soc Clin Oncol Educ Book. 2014;:e101-5. (PMID: 24857086)
J Health Commun. 2015;20(7):790-8. (PMID: 26042588)
Am J Psychiatry. 2009 Nov;166(11):1222-8. (PMID: 19797435)
Int J Epidemiol. 2020 Feb 1;49(1):17-17j. (PMID: 31038687)
J Med Internet Res. 2016 Nov 7;18(11):e286. (PMID: 27821383)
Int J Surg. 2014 Dec;12(12):1500-24. (PMID: 25046751)
Biol Psychiatry. 2003 Jun 1;53(11):1028-42. (PMID: 12788248)
J Health Care Poor Underserved. 2009 May;20(2 Suppl):24-39. (PMID: 19711491)
Cancer. 2008 Jan 1;112(1):212-9. (PMID: 18008353)
J Med Internet Res. 2020 Oct 26;22(10):e22810. (PMID: 33104015)
Cureus. 2023 May 2;15(5):e38417. (PMID: 37273368)
فهرسة مساهمة: Keywords: anxiety; clinical trial awareness; clinical trial engagement; depression; mental health; united states
تواريخ الأحداث: Date Created: 20230724 Latest Revision: 20230725
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10362504
DOI: 10.7759/cureus.40780
PMID: 37485134
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.40780