دورية أكاديمية
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Rapeseed bee pollen alleviates chronic non-bacterial prostatitis via regulating gut microbiota.

التفاصيل البيبلوغرافية
العنوان: Rapeseed bee pollen alleviates chronic non-bacterial prostatitis via regulating gut microbiota.
المؤلفون: Qiao J; State Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.; Terra Research Center, Gembloux Agro-Bio Tech, University of Liege, Gembloux, Belgium., Xiao X; State Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China., Wang K; State Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.; Terra Research Center, Gembloux Agro-Bio Tech, University of Liege, Gembloux, Belgium., Haubruge E; Terra Research Center, Gembloux Agro-Bio Tech, University of Liege, Gembloux, Belgium., Dong J; State Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.; Key Laboratory of Bee Products for Quality and Safety Control, Ministry of Agriculture and Rural Affairs, Beijing, China., Zhang H; State Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.; Key Laboratory of Bee Products for Quality and Safety Control, Ministry of Agriculture and Rural Affairs, Beijing, China.
المصدر: Journal of the science of food and agriculture [J Sci Food Agric] 2023 Dec; Vol. 103 (15), pp. 7896-7904. Date of Electronic Publication: 2023 Aug 07.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 0376334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0010 (Electronic) Linking ISSN: 00225142 NLM ISO Abbreviation: J Sci Food Agric Subsets: MEDLINE
أسماء مطبوعة: Publication: <2005-> : Chichester, West Sussex : John Wiley & Sons
Original Publication: London, Society of Chemical Industry.
مواضيع طبية MeSH: Prostatitis*/drug therapy , Prostatitis*/metabolism , Gastrointestinal Microbiome* , Brassica napus* , Brassica rapa*, Humans ; Male ; Bees ; Animals ; Pollen/metabolism ; Bacteria/genetics
مستخلص: Background: Rapeseed bee pollen has been recognized as a critical treatment for chronic non-bacterial prostatitis (CNP) and it also can modulate gut microbiota and improve gut health. This study aimed to explore the anti-prostatitis effects of rapeseed bee pollen with or without wall-disruption, and to investigate the connection between this treatment and gut microbiota.
Results: The results reveal that rapeseed bee pollen can effectively alleviate chronic non-bacteria prostatitis by selectively regulating gut microbiota, with higher doses and wall-disrupted pollen showing greater efficacy. Treatment with a high dose of wall-disrupted rapeseed bee pollen (WDH, 1.26 g kg -1 body weight) reduced prostate wet weight and prostate index by approximately 32% and 36%, respectively, nearly the levels observed in the control group. Wall-disrupted rapeseed bee pollen treatment also reduced significantly (p < 0.05) the expression of proinflammatory cytokines (IL-6, IL-8, IL-1β, and TNF-α), as confirmed by immunofluorescence with laser scanning confocal microscope. Our results show that rapeseed bee pollen can inhibit pathogenic bacteria and enhance probiotics, particularly in the Firmicutes-to-Bacteroidetes (F/B) ratio and the abundance of Prevotella (genus).
Conclusion: This is the first study to investigate the alleviation of CNP with rapeseed bee pollen through gut microbiota. These results seem to provide better understanding for the development of rapeseed bee pollen as a complementary medicine. © 2023 Society of Chemical Industry.
(© 2023 Society of Chemical Industry.)
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معلومات مُعتمدة: by the China Agriculture Research System of MOF and MARA of P. R. China (CARS 44 KXJ19); the Agricultural Science and Technology Innovation Program (CAAS ASTIP 2019 IAR)
فهرسة مساهمة: Keywords: chronic non-bacterial prostatitis; gut microbiota; rapeseed bee pollen; wall-disruption
تواريخ الأحداث: Date Created: 20230724 Date Completed: 20231114 Latest Revision: 20231114
رمز التحديث: 20231215
DOI: 10.1002/jsfa.12878
PMID: 37486857
قاعدة البيانات: MEDLINE
الوصف
تدمد:1097-0010
DOI:10.1002/jsfa.12878