دورية أكاديمية
Causalgia: A Review of Nerve Resection, Amputation, Immunotherapy, and Amputated Limb CRPS II Pathology.
| العنوان: | Causalgia: A Review of Nerve Resection, Amputation, Immunotherapy, and Amputated Limb CRPS II Pathology. |
|---|---|
| المؤلفون: | Watson CPN; University of Toronto, Toronto, ON, Canada., Midha R; Department of Clinical Neurosciences, Section of Neurosurgery, University of Calgary, Calgary, AB, Canada., Ng DW; Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, Canada. |
| المصدر: | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques [Can J Neurol Sci] 2024 May; Vol. 51 (3), pp. 351-356. Date of Electronic Publication: 2023 Jul 25. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: published by Cambridge University Press for the Canadian Neurological Sciences Federation Country of Publication: England NLM ID: 0415227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0317-1671 (Print) Linking ISSN: 03171671 NLM ISO Abbreviation: Can J Neurol Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <1999>- : Cambridge : published by Cambridge University Press for the Canadian Neurological Sciences Federation Original Publication: Calgary : Canadian Journal of Neurological Sciences |
| مواضيع طبية MeSH: | Amputation, Surgical* , Causalgia*/surgery, Humans ; Immunotherapy/methods ; Complex Regional Pain Syndromes/surgery ; Neurosurgical Procedures/methods |
| مستخلص: | Background: Causalgia and complex regional pain syndrome (CRPS) type II with nerve injury can be difficult to treat. Surgical peripheral nerve denervation for causalgia has been largely abandoned by pain clinicians because of a perception that this may aggravate a central component (anesthesia dolorosa). Methods: We selectively searched Pubmed, Cochrane, MEDLINE, EMBASE, CINAHL Plus, and Scopus from 1947 for articles, books, and book chapters for evidence of surgical treatments (nerve resection and amputation) and treatment related to autoimmunity and immune deficiency with CRPS. Results: Reviews were found for the treatment of causalgia or CRPS type II ( n = 6), causalgia relieved by nerve resection ( n = 6), and causalgia and CRPS II treated by amputation ( n = 8). Twelve reports were found of autoimmunity with CRPS, one paper of these on associated immune deficiency and autoimmunity, and two were chosen for discussion regarding treatment with immunoglobulin and one by plasma exchange. We document a report of a detailed and unique pathological examination of a CRPS type II affected amputated limb and related successful treatment with immunoglobulin. Conclusions: Nerve resection, with grafting, and relocation may relieve uncomplicated causalgia and CRPS type II in some patients in the long term. However, an unrecognized and treatable immunological condition may underly some CRPS II cases and can lead to the ultimate failure of surgical treatments. |
| فهرسة مساهمة: | Keywords: Causalgia; amputation pathology; autoimmunity; complex regional pain syndrome type II (CRPS II); immune deficiency; intravenous immunoglobulin (IVIg); nerve resection/relocation; neuropathic pain (NeP); randomized controlled trial (RCT); regenerative peripheral nerve interface (RPNI); surgical treatment; targeted motor reinnervation (TMR) |
| تواريخ الأحداث: | Date Created: 20230725 Date Completed: 20240807 Latest Revision: 20240807 |
| رمز التحديث: | 20240807 |
| DOI: | 10.1017/cjn.2023.260 |
| PMID: | 37489506 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0317-1671 |
|---|---|
| DOI: | 10.1017/cjn.2023.260 |