دورية أكاديمية
Allergic rhinitis behavioral changes after Indonesian house dust mites allergenic extract administration as immunotherapy.
| العنوان: | Allergic rhinitis behavioral changes after Indonesian house dust mites allergenic extract administration as immunotherapy. |
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| المؤلفون: | Pratama YA; Master Program of Pharmaceutical Science, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia., Marhaeny HD; Master Program of Pharmaceutical Science, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia., Rohmah L; Bachelor Program of Pharmacy, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia., Kasatu SM; Bachelor Program of Pharmacy, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia., Nurhan AD; Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia., Rahmadi M; Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia., Khotib J; Department of Pharmacy Practice, Faculty of Pharmacy, Universitas Airlangga, Surabaya, Indonesia. |
| المصدر: | Journal of public health in Africa [J Public Health Afr] 2023 Mar 16; Vol. 14 (Suppl 1), pp. 2510. Date of Electronic Publication: 2023 Mar 16 (Print Publication: 2023). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: PAGEPress Country of Publication: Italy NLM ID: 101586943 Publication Model: eCollection Cited Medium: Print ISSN: 2038-9922 (Print) Linking ISSN: 20389922 NLM ISO Abbreviation: J Public Health Afr Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Pavia, Italy : PAGEPress |
| مستخلص: | Background: Allergy is a hypersensitivity reaction that is generally mediated by Immunoglobulin E (IgE). More than 25% of the world's population is suspected of having these various diseases, and the prevalence and progression of these diseases have continued to increase significantly in recent years. Among these allergyrelated diseases, allergic rhinitis and food allergy are the types of allergies with the highest prevalence. Clinical manifestations of allergic rhinitis include sneezing, rhinorrhea, nasal itching, and nasal congestion. Objective: This study aimed to determine the behavioral changes of allergic rhinitis after Indonesian House Dust Mites (IHDM) allergenic extract administration as an immunotherapy. Methods: Eight male BALB/c mice aged 6-8 weeks in each group were treated for seven groups. The sensitization phase is given intraperitoneal, the desensitization phase is given by subcutaneous, and the challenge phase is given intranasal. The allergic parameters were observed, such as nose rubbing and sneezing. The parameters were observed for 15 minutes after the challenge administration. Results: The results showed that the administration of Indonesian House Dust Mites as immunotherapy decreased the frequency of nose rubbing and sneezing after the administration of immunotherapy compared to the allergic rhinitis model. Conclusions: The administration of the Indonesian House Dust Mites as immunotherapy decreased the allergic rhinitis immune response by altering the behavioral parameter. Competing Interests: Conflict of interest: The authors declare no potential conflict of interest. (©Copyright: the Author(s).) |
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| فهرسة مساهمة: | Keywords: Desensitization; IHDM; neglected disease; phenotype; sneezing |
| تواريخ الأحداث: | Date Created: 20230726 Latest Revision: 20230727 |
| رمز التحديث: | 20240829 |
| مُعرف محوري في PubMed: | PMC10365652 |
| DOI: | 10.4081/jphia.2023.2510 |
| PMID: | 37492532 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2038-9922 |
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| DOI: | 10.4081/jphia.2023.2510 |