دورية أكاديمية
Nutrient supplementation of beef female calves at pre-weaning enhances the commitment of fibro-adipogenic progenitor cells to preadipocytes.
| العنوان: | Nutrient supplementation of beef female calves at pre-weaning enhances the commitment of fibro-adipogenic progenitor cells to preadipocytes. |
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| المؤلفون: | Santos MM; Department of Animal Science, Universidade Federal de Viçosa, Viçosa, Brazil; Muscle Biology and Nutrigenomics Laboratory, Universidade Federal de Viçosa, Viçosa, Brazil., Costa TC; Muscle Biology and Nutrigenomics Laboratory, Universidade Federal de Viçosa, Viçosa, Brazil; Department of Animal Science, Universidade Federal de Lavras, Lavras, MG, Brazil., Silva W; Department of Animal Science, Universidade Federal de Viçosa, Viçosa, Brazil; Department of Animal Biosciences, University of Guelph, Guelph, ON, Canada., Pistillo LZ; Department of Animal Science, Universidade Federal de Viçosa, Viçosa, Brazil., Junior DTV; Department of Animal Science, Universidade Federal de Viçosa, Viçosa, Brazil; Muscle Biology and Nutrigenomics Laboratory, Universidade Federal de Viçosa, Viçosa, Brazil; Department of Animal Biosciences, University of Guelph, Guelph, ON, Canada., Verardo LL; Department of Animal Science, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Brazil., Paulino PVR; Cargill Animal Nutrition, Campinas, SP, Brazil., Sampaio CB; Department of Animal Science, Universidade Federal de Viçosa, Viçosa, Brazil., Gionbelli MP; Department of Animal Science, Universidade Federal de Lavras, Lavras, MG, Brazil., Du M; Department of Animal Sciences, Washington State University, Pullman, WA, USA., Duarte MS; Department of Animal Biosciences, University of Guelph, Guelph, ON, Canada. Electronic address: mduarte@uoguelph.ca. |
| المصدر: | Meat science [Meat Sci] 2023 Oct; Vol. 204, pp. 109286. Date of Electronic Publication: 2023 Jul 20. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 101160862 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4138 (Electronic) Linking ISSN: 03091740 NLM ISO Abbreviation: Meat Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <200?>- : Oxford : Elsevier Original Publication: Barking, Essex, Eng., Applied Science Publishers |
| مواضيع طبية MeSH: | Diet*/veterinary , MicroRNAs*, Cattle ; Animals ; Female ; Weaning ; Animal Feed/analysis ; Dietary Supplements ; Body Weight ; Nutrients |
| مستخلص: | We aimed to evaluate the impact of nutrient supplementation of beef female calves at pre-weaning on adipogenic determination. Thirty-four female calves were assigned to two experimental treatments: Control (CON, n = 17), where animals were supplemented only with mineral mixture; Supplemented (SUP, n = 17), where animals received energy-protein supplement containing minerals (5 g/kg of BW per day) of their body weight. Animals were supplemented from 100 to 250 days of age, and muscle samples were biopsied at the end of the supplementation period. Regarding the performance variables, there were no differences between treatments for initial body weight (P = 0.75). The final body weight (P = 0.07), average daily gain (P = 0.07), rib eye area (P = 0.03), and rib fat thickness (P = 0.08) were greater in SUP female calves compared with CON treatment. The number of fibro-adipogenic progenitor cells (P = 0.69) did not differ between treatments, while a greater number of intramuscular pre-adipocytes were observed in SUP than CON female calves (P = 0.01). The expression of miRNA-4429 (P = 0.20) did not differ between treatments, while the expression of miRNA-129-5p (P = 0.09) and miRNA-129-2-3p (P = 0.05) was greater in CON than SUP female calves. Our results suggest that nutrient supplementation at early postnatal stages of development enhances the commitment of fibro-adipogenic progenitor cells into the adipogenic lineages allowing to an increase in intramuscular fat deposition potential of the animals later in life. Competing Interests: Declaration of Competing Interest The authors have no conflict of interest to declare. (Copyright © 2023 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Female calves; Marbling; Preadipocytes; Transcriptional factor; microRNA |
| المشرفين على المادة: | 0 (MicroRNAs) |
| تواريخ الأحداث: | Date Created: 20230726 Date Completed: 20230809 Latest Revision: 20230809 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.meatsci.2023.109286 |
| PMID: | 37494740 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-4138 |
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| DOI: | 10.1016/j.meatsci.2023.109286 |