دورية أكاديمية

The Skin and Natural Cannabinoids-Topical and Transdermal Applications.

التفاصيل البيبلوغرافية
العنوان: The Skin and Natural Cannabinoids-Topical and Transdermal Applications.
المؤلفون: Filipiuc SI; Advanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy, Universitatii Street, 16, 700115 Iasi, Romania.; Department of Physiology, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania., Neagu AN; Laboratory of Animal Histology, Faculty of Biology, 'Alexandru Ioan Cuza' University of Iasi, Carol I bvd, No. 20A, 700505 Iasi, Romania., Uritu CM; Advanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy, Universitatii Street, 16, 700115 Iasi, Romania., Tamba BI; Advanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy, Universitatii Street, 16, 700115 Iasi, Romania.; Department of Pharmacology, Clinical Pharmacology and Algesiology, Grigore T. Popa University of Medicine and Pharmacy, Universitatii Street, 16, 700115 Iasi, Romania., Filipiuc LE; Advanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy, Universitatii Street, 16, 700115 Iasi, Romania.; Department of Pharmacology, Clinical Pharmacology and Algesiology, Grigore T. Popa University of Medicine and Pharmacy, Universitatii Street, 16, 700115 Iasi, Romania., Tudorancea IM; Advanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy, Universitatii Street, 16, 700115 Iasi, Romania.; Department of Pharmacology, Clinical Pharmacology and Algesiology, Grigore T. Popa University of Medicine and Pharmacy, Universitatii Street, 16, 700115 Iasi, Romania., Boca AN; Department of Pharmacology, Toxicology and Clinical Pharmacology, Iuliu Hatieganu University of Medicine and Pharmacy, 400347 Cluj-Napoca, Romania., Hâncu MF; Arcadia Policlinic, 700083 Iași, Romania., Porumb V; Department Surgery, Grigore T. Popa University of Medicine and Pharmacy, Universitatii Street, 16, 700115 Iasi, Romania., Bild W; Department of Physiology, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.; Center of Biomedical Research of the Romanian Academy, 700506 Iasi, Romania.
المصدر: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Jul 24; Vol. 16 (7). Date of Electronic Publication: 2023 Jul 24.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238453 Publication Model: Electronic Cited Medium: Print ISSN: 1424-8247 (Print) Linking ISSN: 14248247 NLM ISO Abbreviation: Pharmaceuticals (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, c2004-
مستخلص: The chemical constituents of the Cannabis plant known as cannabinoids have been extensively researched for their potential therapeutic benefits. The use of cannabinoids applied to the skin as a potential method for both skin-related benefits and systemic administration has attracted increasing interest in recent years. This review aims to present an overview of the most recent scientific research on cannabinoids used topically, including their potential advantages for treating a number of skin conditions like psoriasis, atopic dermatitis, and acne. Additionally, with a focus on the pharmacokinetics and security of this route of administration, we investigate the potential of the transdermal delivery of cannabinoids as a method of systemic administration. The review also discusses the restrictions and difficulties related to the application of cannabinoids on the skin, emphasizing the potential of topical cannabinoids as a promising route for both localized and systemic administration. More studies are required to fully comprehend the efficacy and safety of cannabinoids in various settings.
References: J Eur Acad Dermatol Venereol. 2008 Jan;22(1):73-82. (PMID: 18181976)
J Eur Acad Dermatol Venereol. 2022 Jul;36(7):1088-1096. (PMID: 35274366)
Med Hypotheses. 2017 Feb;99:15-18. (PMID: 28110689)
Ther Adv Musculoskelet Dis. 2020 Jul 2;12:1759720X20937968. (PMID: 32655704)
Handb Exp Pharmacol. 2005;(168):657-90. (PMID: 16596792)
Clin Dermatol. 2021 Sep-Oct;39(5):784-795. (PMID: 34785006)
Neurotherapeutics. 2015 Oct;12(4):731-4. (PMID: 26202343)
J Altern Complement Med. 2014 May;20(5):392-8. (PMID: 24517329)
Braz J Psychiatry. 2006 Jun;28(2):153-7. (PMID: 16810401)
Drugs. 2021 Sep;81(13):1513-1557. (PMID: 34480749)
Fa Yi Xue Za Zhi. 2010 Aug;26(4):241-5. (PMID: 20967946)
Eur J Pharm Biopharm. 2008 Oct;70(2):633-40. (PMID: 18577447)
Cannabis Cannabinoid Res. 2020 Dec 15;5(4):279-282. (PMID: 33381641)
Planta Med. 2012 May;78(7):686-91. (PMID: 22411724)
J Invest Dermatol. 2015 Jun;135(6):1510-1520. (PMID: 25668241)
Cannabis Cannabinoid Res. 2018 Oct 01;3(1):203-212. (PMID: 30426073)
Orphanet J Rare Dis. 2021 Sep 6;16(1):377. (PMID: 34488820)
Eur J Pharm Sci. 2020 Aug 1;151:105410. (PMID: 32505795)
Drug Dev Ind Pharm. 2010 Sep;36(9):1088-97. (PMID: 20545522)
Int J Mol Sci. 2023 Feb 01;24(3):. (PMID: 36769042)
Clin Exp Pharmacol Physiol. 1997 Nov;24(11):874-9. (PMID: 9363373)
Biomolecules. 2020 May 13;10(5):. (PMID: 32414087)
Eur J Pharmacol. 2016 Sep 5;786:128-136. (PMID: 27268717)
Hum Reprod Update. 2007 Sep-Oct;13(5):501-13. (PMID: 17584820)
Polymers (Basel). 2021 Jan 08;13(2):. (PMID: 33435623)
Dermatol Online J. 2018 Jun 15;24(6):. (PMID: 30142706)
Neuropsychopharmacology. 2018 Sep;43(10):2036-2045. (PMID: 29686308)
Microorganisms. 2017 Jun 07;5(2):. (PMID: 28590443)
Reprod Toxicol. 2020 Jun;94:84-91. (PMID: 32325173)
Eur J Pharm Sci. 2018 Jan 15;112:159-167. (PMID: 29183800)
Hautarzt. 2006 Sep;57(9):801-7. (PMID: 16874533)
J Dermatolog Treat. 2023 Dec;34(1):2127308. (PMID: 36200741)
Am Fam Physician. 2020 May 15;101(10):590-598. (PMID: 32412211)
Microorganisms. 2021 Feb 20;9(2):. (PMID: 33672633)
Allergy. 2013 Aug;68(8):994-1000. (PMID: 23889474)
Eur J Pharm Sci. 2021 Apr 1;159:105698. (PMID: 33406408)
Pharmaceutics. 2020 Jul 20;12(7):. (PMID: 32698388)
Mol Carcinog. 2016 Nov;55(11):1807-1821. (PMID: 26513129)
Molecules. 2019 Aug 16;24(16):. (PMID: 31426272)
Antibiotics (Basel). 2020 Jun 02;9(6):. (PMID: 32498408)
Oral Dis. 2016 May;22(4):253-9. (PMID: 26464123)
J Eur Acad Dermatol Venereol. 2005 May;19(3):319-22. (PMID: 15857457)
Sci Rep. 2016 Sep 19;6:33302. (PMID: 27641999)
Expert Opin Drug Metab Toxicol. 2016;12(4):377-88. (PMID: 26854731)
Pharmaceuticals (Basel). 2021 Jan 06;14(1):. (PMID: 33418866)
Neuropsychopharmacology. 2018 Jan;43(1):52-79. (PMID: 28857069)
Clin Ter. 2019 Mar-Apr;170(2):e93-e99. (PMID: 30993303)
Adv Ther. 2019 Nov;36(11):3196-3210. (PMID: 31512143)
J Invest Dermatol. 2012 Aug;132(8):1967-76. (PMID: 22513781)
J Biol Chem. 2003 Sep 5;278(36):33896-903. (PMID: 12815050)
Allergy. 2014 Oct;69(10):1275-9. (PMID: 24965386)
Eur J Pharm Biopharm. 2001 Sep;52(2):103-12. (PMID: 11522474)
FASEB J. 2008 Oct;22(10):3685-95. (PMID: 18596221)
Neurochem Res. 2005 Aug;30(8):1037-43. (PMID: 16258853)
J Biol Chem. 2008 Mar 7;283(10):6005-12. (PMID: 18165231)
Front Vet Sci. 2022 Apr 28;9:892306. (PMID: 35573415)
J Dermatol Sci. 2007 Feb;45(2):87-92. (PMID: 17157480)
J Pharm Pharmacol. 2006 Apr;58(4):415-29. (PMID: 16597359)
Int J Mol Sci. 2023 Jan 25;24(3):. (PMID: 36768709)
J Pharm Pharmacol. 1976 Jan;28(1):1-7. (PMID: 6643)
Indian J Dermatol Venereol Leprol. 2012 Sep-Oct;78(5):552-9. (PMID: 22960810)
Molecules. 2022 Sep 17;27(18):. (PMID: 36144803)
Cureus. 2022 Apr 5;14(4):e23850. (PMID: 35530920)
Skin Pharmacol Physiol. 2014;27(5):263-75. (PMID: 24943921)
Pharmaceuticals (Basel). 2021 Dec 28;15(1):. (PMID: 35056095)
Pharmaceutics. 2022 Mar 25;14(4):. (PMID: 35456536)
Curr Drug Metab. 2016;17(3):206-26. (PMID: 26651971)
Int J Dermatol. 2015 Oct;54(10):e401-8. (PMID: 26095080)
J Dermatol Sci. 2016 Feb;81(2):107-17. (PMID: 26674123)
Phytother Res. 2019 Aug;33(8):2083-2093. (PMID: 31250491)
J Pharmacol Exp Ther. 2018 Jun;365(3):652-663. (PMID: 29632236)
Skin Pharmacol. 1990;3(1):21-8. (PMID: 2390261)
Expert Opin Emerg Drugs. 2014 Dec;19(4):441-58. (PMID: 25286776)
Clin Med (Lond). 2021 May;21(3):170-173. (PMID: 34001566)
Expert Opin Investig Drugs. 2019 Mar;28(3):285-296. (PMID: 30572744)
Indian Dermatol Online J. 2014 Oct;5(4):416-25. (PMID: 25396122)
Molecules. 2019 Mar 06;24(5):. (PMID: 30845666)
Exp Dermatol. 2021 Sep;30(9):1258-1267. (PMID: 34013652)
Int J Pharm. 2021 Jul 15;604:120766. (PMID: 34087415)
Prog Chem Org Nat Prod. 2017;103:1-36. (PMID: 28120229)
J Clin Investig Dermatol. 2015 Dec;3(2):. (PMID: 27148560)
Neuropsychopharmacology. 2021 Apr;46(5):1004-1010. (PMID: 33070154)
J Eur Acad Dermatol Venereol. 2014 Jan;28(1):16-26. (PMID: 23802806)
J Dermatol Sci. 2005 Jun;38(3):177-88. (PMID: 15927811)
Pharmaceutics. 2021 Nov 01;13(11):. (PMID: 34834237)
Perm J. 2020 Dec;25:1-3. (PMID: 33635755)
Acta Dermatovenerol Croat. 2005;13(2):97-103. (PMID: 16324422)
Pharmaceutics. 2023 Feb 06;15(2):. (PMID: 36839859)
Antioxidants (Basel). 2019 Dec 25;9(1):. (PMID: 31881765)
PeerJ. 2013 Feb 19;1:e40. (PMID: 23638377)
J Cosmet Dermatol. 2021 Sep;20(9):2703-2711. (PMID: 34363728)
Clin Chem Lab Med. 2018 Mar 28;56(4):94-96. (PMID: 29176009)
J Dermatolog Treat. 2020 Dec;31(8):839-845. (PMID: 31599175)
J Control Release. 2016 Oct 28;240:77-92. (PMID: 26518723)
Clin Cosmet Investig Dermatol. 2015 Oct 05;8:511-20. (PMID: 26491366)
Syst Rev. 2020 Sep 28;9(1):222. (PMID: 32988419)
Br J Clin Pharmacol. 2018 Nov;84(11):2477-2482. (PMID: 30001569)
J Mater Chem B. 2015 Nov 14;3(42):8250-8267. (PMID: 32262881)
Biomed Pharmacother. 2018 Dec;108:1477-1494. (PMID: 30372850)
ACS Omega. 2022 Jul 12;7(29):25741-25750. (PMID: 35910111)
Front Plant Sci. 2020 Jun 25;11:718. (PMID: 32670310)
Plast Reconstr Surg. 2006 Jun;117(7 Suppl):12S-34S. (PMID: 16799372)
Experientia. 1981 Oct 15;37(10):1090-2. (PMID: 6273208)
Planta Med. 2022 Jun;88(7):492-506. (PMID: 33851375)
Oncotarget. 2020 Mar 31;11(13):1141-1156. (PMID: 32284791)
Adv Pharmacol. 2017;80:223-247. (PMID: 28826536)
Trends Immunol. 2018 Apr;39(4):315-327. (PMID: 29551468)
Br J Dermatol. 2018 Jun;178(6):1469. (PMID: 29897115)
Epilepsia. 2015 Aug;56(8):1246-51. (PMID: 26114620)
Dermatol Ther (Heidelb). 2017 Mar;7(1):1-23. (PMID: 28025775)
JAAD Case Rep. 2021 Sep 20;17:38-42. (PMID: 34692966)
Pharmacol Biochem Behav. 2013 Oct;111:120-7. (PMID: 24012796)
J Pharmacol Exp Ther. 1990 Nov;255(2):624-30. (PMID: 2173751)
Antioxidants (Basel). 2023 Feb 14;12(2):. (PMID: 36830042)
Front Plant Sci. 2020 Oct 15;11:583605. (PMID: 33178249)
Biochem Pharmacol. 2018 Nov;157:122-133. (PMID: 30138623)
Methods Find Exp Clin Pharmacol. 2000 Mar;22(2):129-33. (PMID: 10849897)
Dermatol Ther. 2004;17(4):334-40. (PMID: 15327479)
Molecules. 2023 Jan 25;28(3):. (PMID: 36770858)
Dermatitis. 2021 Oct 1;32(1S):S62-S70. (PMID: 33323748)
J Clin Pharmacol. 2002 Nov;42(S1):11S-19S. (PMID: 12412831)
Skin Pharmacol Physiol. 2005 Sep-Oct;18(5):209-19. (PMID: 16015019)
Clin Cosmet Investig Dermatol. 2019 Mar 21;12:181-192. (PMID: 30962700)
J Clin Invest. 2014 Sep;124(9):3713-24. (PMID: 25061872)
Molecules. 2014 Dec 12;19(12):20780-807. (PMID: 25514222)
Commun Biol. 2021 Jan 19;4(1):7. (PMID: 33469147)
Pharmaceutics. 2015 Oct 22;7(4):438-70. (PMID: 26506371)
Nat Rev Neurosci. 2016 May;17(5):293-306. (PMID: 27052382)
Einstein (Sao Paulo). 2022 Feb 14;20:eRC5795. (PMID: 35170710)
Br J Pharmacol. 2004 Sep;143(2):247-50. (PMID: 15313881)
Medicines (Basel). 2019 Feb 23;6(1):. (PMID: 30813390)
J Inflamm Res. 2022 May 03;15:2795-2801. (PMID: 35535052)
Mol Pain. 2017 Jan;13:1744806916688220. (PMID: 28326930)
Med Cannabis Cannabinoids. 2022 Oct 10;5(1):129-137. (PMID: 36467778)
Eur J Pain. 2016 Jul;20(6):936-48. (PMID: 26517407)
Asia Pac Allergy. 2016 Apr;6(2):120-8. (PMID: 27141486)
Clin Cosmet Investig Dermatol. 2020 Dec 08;13:927-942. (PMID: 33335413)
Int J Legal Med. 2012 Sep;126(5):807-14. (PMID: 22814434)
Exp Dermatol. 2016 Sep;25(9):701-7. (PMID: 27094344)
Life Sci. 2019 May 1;224:120-127. (PMID: 30910646)
An Bras Dermatol. 2021 May-Jun;96(3):295-300. (PMID: 33775478)
Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):2167-2179. (PMID: 28399267)
Free Radic Biol Med. 2021 Feb 20;164:258-270. (PMID: 33453360)
Pharmaceuticals (Basel). 2022 Feb 09;15(2):. (PMID: 35215320)
Mol Carcinog. 2016 Feb;55(2):117-30. (PMID: 25557612)
Behav Brain Res. 2018 Nov 1;353:11-20. (PMID: 29953903)
Pediatr Dermatol. 2018 Jul;35(4):e224-e227. (PMID: 29786144)
Chem Biodivers. 2007 Aug;4(8):1614-48. (PMID: 17712811)
J Anal Toxicol. 2021 Nov 9;45(9):969-975. (PMID: 33064813)
Drug Deliv. 2006 May-Jun;13(3):175-87. (PMID: 16556569)
Curr Dermatol Rep. 2018;7(4):350-358. (PMID: 30524911)
Medicina (Kaunas). 2020 Jan 09;56(1):. (PMID: 31936616)
Cannabis Cannabinoid Res. 2016 Oct 01;1(1):234-238. (PMID: 28861494)
S Afr Fam Pract (2004). 2022 May 30;64(1):e1-e4. (PMID: 35695447)
Med Cannabis Cannabinoids. 2022 Jul 25;5(1):102-119. (PMID: 36467783)
J Control Release. 2021 Jun 10;334:427-451. (PMID: 33964365)
Pharmaceutics. 2023 Feb 28;15(3):. (PMID: 36986659)
J Am Acad Dermatol. 2017 Jul;77(1):188-190. (PMID: 28416341)
Mol Psychiatry. 2013 Oct;18(10):1125-35. (PMID: 22776900)
Adv Drug Deliv Rev. 2007 Sep 30;59(11):1152-61. (PMID: 17889400)
Pharmaceutics. 2021 Dec 13;13(12):. (PMID: 34959427)
Paediatr Drugs. 2013 Aug;15(4):303-10. (PMID: 23549982)
Adv Exp Med Biol. 2019;1162:1-12. (PMID: 31332731)
Exp Dermatol. 2014 Jun;23(6):401-6. (PMID: 24750433)
Pharmaceutics. 2022 Feb 18;14(2):. (PMID: 35214170)
Ther Deliv. 2014 Jun;5(6):635-52. (PMID: 25090278)
Int J Mol Sci. 2022 Mar 19;23(6):. (PMID: 35328765)
Molecules. 2018 Sep 27;23(10):. (PMID: 30262735)
Pak J Pharm Sci. 2015 Jul;28(4):1389-95. (PMID: 26142529)
Neural Plast. 2016;2016:9364091. (PMID: 26881140)
Phytother Res. 2023 Apr;37(4):1526-1538. (PMID: 36748949)
J Med Chem. 2022 Jul 28;65(14):9918-9938. (PMID: 35849804)
J Control Release. 2014 Sep 28;190:15-28. (PMID: 24747160)
Int J Mol Sci. 2020 Aug 21;21(17):. (PMID: 32839414)
J Pharm Sci. 2005 May;94(5):1149-59. (PMID: 15793804)
Br J Pharmacol. 2006 Jan;147 Suppl 1:S163-71. (PMID: 16402100)
J Chromatogr. 1991 Jan 2;562(1-2):299-322. (PMID: 2026700)
Molecules. 2016 Aug 13;21(8):. (PMID: 27529209)
Life Sci. 2011 Aug 1;89(5-6):165-70. (PMID: 21704641)
Curr Drug Deliv. 2019;16(5):444-460. (PMID: 30714524)
Regul Toxicol Pharmacol. 2015 Jul;72(2):310-22. (PMID: 25979643)
Cells. 2022 Dec 06;11(23):. (PMID: 36497198)
Drug Des Devel Ther. 2020 Aug 12;14:3271-3289. (PMID: 32848366)
معلومات مُعتمدة: PN-III-P4-ID-PCE-2020-1247 Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii
فهرسة مساهمة: Keywords: delivery systems; nano-formulations; natural cannabinoids; phytocannabinoids; skin endocannabinoid system; topical cannabinoids; transdermal administration
تواريخ الأحداث: Date Created: 20230729 Latest Revision: 20230801
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10386449
DOI: 10.3390/ph16071049
PMID: 37513960
قاعدة البيانات: MEDLINE
الوصف
تدمد:1424-8247
DOI:10.3390/ph16071049