دورية أكاديمية
أعرض في EDS

Functional training improves peak oxygen consumption and quality of life of individuals with heart failure: a randomized clinical trial.

التفاصيل البيبلوغرافية
العنوان: Functional training improves peak oxygen consumption and quality of life of individuals with heart failure: a randomized clinical trial.
المؤلفون: do Nascimento DM; Exercise Pathophysiology Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil. dnascimento903@gmail.com., Machado KC; Exercise Pathophysiology Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Bock PM; Exercise Pathophysiology Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.; Clinical Research Center, National Institute of Science and Technology for Health Technology Assessment (IATS) - CNPq/Brazil, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, Porto Alegre, RS, 2350, Brazil.; Faculdades Integradas de Taquara, Taquara, RS, Brazil., Saffi MAL; Exercise Pathophysiology Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Goldraich LA; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Silveira AD; Exercise Pathophysiology Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Clausell N; Medical School, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Schaan BD; Exercise Pathophysiology Laboratory, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.; Clinical Research Center, National Institute of Science and Technology for Health Technology Assessment (IATS) - CNPq/Brazil, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, Porto Alegre, RS, 2350, Brazil.; Medical School, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
المصدر: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2023 Jul 29; Vol. 23 (1), pp. 381. Date of Electronic Publication: 2023 Jul 29.
نوع المنشور: Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968539 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2261 (Electronic) Linking ISSN: 14712261 NLM ISO Abbreviation: BMC Cardiovasc Disord Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Quality of Life* , Heart Failure*/diagnosis , Heart Failure*/therapy, Humans ; Hand Strength ; Stroke Volume ; Ventricular Function, Left ; Oxygen Consumption
مستخلص: Background: Functional training may be an effective non-pharmacological therapy for heart failure (HF). This study aimed to compare the effects of functional training with strength training on peak VO 2 and quality of life in individuals with HF.
Methods: A randomized, parallel-design and examiner-blinded controlled clinical trial with concealed allocation, intention-to-treat and per-protocol analyses. Twenty-seven participants with chronic HF were randomly allocated to functional or strength training group, to perform a 12-week physical training, three times per week, totalizing 36 sessions. Primary outcomes were the difference on peak VO 2 and quality of life assessed by cardiopulmonary exercise testing and Minnesota Living with Heart Failure Questionnaire, respectively. Secondary outcomes included functionality assessed by the Duke Activity Status Index and gait speed test, peripheral and inspiratory muscular strength, assessed by hand grip and manovacuometry testing, respectively, endothelial function by brachial artery flow-mediated dilation, and lean body mass by arm muscle circumference.
Results: Participants were aged 60 ± 7 years, with left ventricular ejection fraction 29 ± 8.5%. The functional and strength training groups showed the following results, respectively: peak VO 2 increased by 1.4 ± 3.2 (16.9 ± 2.9 to 18.6 ± 4.8 mL.kg -1 .min -1 ; p time = 0.011) and 1.5 ± 2.5 mL.kg -1 .min -1 (16.8 ± 4.0 to 18.6 ± 5.5 mL.kg -1 .min -1 ; p time = 0.011), and quality of life score decreased by 14 ± 15 (25.8 ± 14.8 to 10.3 ± 7.8 points; p time = 0.001) and 12 ± 28 points (33.8 ± 23.8 to 19.0 ± 15.1 points; p time = 0.001), but no difference was observed between groups (peak VO 2 : p interaction = 0.921 and quality of life: p interaction = 0.921). The functional and strength training increased the activity status index by 6.5 ± 12 and 5.2 ± 13 points (p time = 0.001), respectively, and gait speed by 0.2 ± 0.3 m/s (p  time = 0.002) in both groups.
Conclusions: Functional and strength training are equally effective in improving peak VO 2 , quality of life, and functionality in individuals with HF. These findings suggest that functional training may be a promising and innovative exercise-based strategy to treat HF.
Trial Registration: NCT03321682. Registered date: 26/10/2017.
(© 2023. The Author(s).)
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فهرسة مساهمة: Keywords: Cardiac failure; Cardiopulmonary exercise capacity; Exercise; Health-related quality of life
سلسلة جزيئية: ClinicalTrials.gov NCT03321682
تواريخ الأحداث: Date Created: 20230729 Date Completed: 20230731 Latest Revision: 20230801
رمز التحديث: 20230801
مُعرف محوري في PubMed: PMC10386700
DOI: 10.1186/s12872-023-03404-7
PMID: 37516830
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2261
DOI:10.1186/s12872-023-03404-7