دورية أكاديمية
Should oncologists trust cannabinoids?
| العنوان: | Should oncologists trust cannabinoids? |
|---|---|
| المؤلفون: | Creanga-Murariu I; Advanced Research and Development Center for Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, Iași, Romania.; Oncology Department, 'Grigore T. Popa' University of Medicine and Pharmacy, Iași, Romania., Filipiuc LE; Advanced Research and Development Center for Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, Iași, Romania., Cuciureanu M; Pharmacology Department, Clinical Pharmacology and Algesiology, 'Grigore T. Popa' University of Medicine and Pharmacy, Iași, Romania., Tamba BI; Advanced Research and Development Center for Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, Iași, Romania.; Pharmacology Department, Clinical Pharmacology and Algesiology, 'Grigore T. Popa' University of Medicine and Pharmacy, Iași, Romania., Alexa-Stratulat T; Oncology Department, 'Grigore T. Popa' University of Medicine and Pharmacy, Iași, Romania. |
| المصدر: | Frontiers in pharmacology [Front Pharmacol] 2023 Jul 13; Vol. 14, pp. 1211506. Date of Electronic Publication: 2023 Jul 13 (Print Publication: 2023). |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Lausanne : Frontiers Media] |
| مستخلص: | Cannabis enjoyed a "golden age" as a medicinal product in the late 19th, early 20th century, but the increased risk of overdose and abuse led to its criminalization. However, the 21st century have witnessed a resurgence of interest and a large body of literature regarding the benefits of cannabinoids have emerged. As legalization and decriminalization have spread around the world, cancer patients are increasingly interested in the potential utility of cannabinoids. Although eager to discuss cannabis use with their oncologist, patients often find them to be reluctant, mainly because clinicians are still not convinced by the existing evidence-based data to guide their treatment plans. Physicians should prescribe cannabis only if a careful explanation can be provided and follow up response evaluation ensured, making it mandatory for them to be up to date with the positive and also negative aspects of the cannabis in the case of cancer patients. Consequently, this article aims to bring some clarifications to clinicians regarding the sometimes-confusing various nomenclature under which this plant is mentioned, current legislation and the existing evidence (both preclinical and clinical) for the utility of cannabinoids in cancer patients, for either palliation of the associated symptoms or even the potential antitumor effects that cannabinoids may have. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Creanga-Murariu, Filipiuc, Cuciureanu, Tamba and Alexa-Stratulat.) |
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| فهرسة مساهمة: | Keywords: anorexia and cachexia; anxiety and depression; cancer; cannabinoids; cannabis; nausea and vomiting; oncology; pain |
| تواريخ الأحداث: | Date Created: 20230731 Latest Revision: 20230801 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC10373070 |
| DOI: | 10.3389/fphar.2023.1211506 |
| PMID: | 37521486 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1663-9812 |
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| DOI: | 10.3389/fphar.2023.1211506 |