دورية أكاديمية
Impact of secondary amenorrhea on cardiovascular disease risk in physically active women: a systematic review protocol.
| العنوان: | Impact of secondary amenorrhea on cardiovascular disease risk in physically active women: a systematic review protocol. |
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| المؤلفون: | Tegg NL; Faculty of Nursing, University of Alberta, Edmonton, AB, Canada., Myburgh C; Faculty of Natural Sciences, The Kings University, Edmonton, AB, Canada., Kennedy M; University of Alberta Library, Edmonton, AB, Canada., Norris CM; Faculty of Nursing, University of Alberta, Edmonton, AB, Canada.; Cavarzan Chair in Mature Women's Research, Women's and Children's Health Research Institute, Edmonton, AB, Canada.; Faculty of Medicine, School of Public Health Sciences, University of Alberta, Edmonton, AB, Canada. |
| المصدر: | JBI evidence synthesis [JBI Evid Synth] 2024 Feb 01; Vol. 22 (2), pp. 343-350. Date of Electronic Publication: 2024 Feb 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 101764819 Publication Model: Electronic Cited Medium: Internet ISSN: 2689-8381 (Electronic) Linking ISSN: 26898381 NLM ISO Abbreviation: JBI Evid Synth |
| أسماء مطبوعة: | Original Publication: [Philadelphia, PA] : Wolters Kluwer, [2020]- |
| مواضيع طبية MeSH: | Cardiovascular Diseases*/epidemiology , Cardiovascular Diseases*/etiology , Systematic Reviews as Topic* , Amenorrhea*/epidemiology , Amenorrhea*/etiology , Exercise*, Humans ; Female ; Heart Disease Risk Factors ; Risk Factors |
| مستخلص: | Objective: The objective of this review is to assess the association between secondary amenorrhea in physically active women and cardiovascular disease risk. Introduction: It is well established that a woman's risk of cardiovascular disease greatly increases after menopause. The sharp decline in estrogen is seen as a causal factor. Exercise-induced secondary amenorrhea results in estrogen deficiency, which may lead to dysfunction in estrogen's cardioprotective pathways. Further, estrogen may be essential in a woman's endothelial adaptations to exercise. The impact of secondary amenorrhea on cardiovascular disease risk in premenopausal women is not well established. Inclusion Criteria: This review will consider studies that include physically active women experiencing amenorrhea in any country. Only studies that present evidence of cardiovascular disease, alterations to cardiovascular physiology, or data on cardiovascular risk factors (eg, lipid profile changes) will be considered. The review will consider experimental or observational epidemiological study designs. Methods: Searches will be conducted in CINAHL (EBSCOhost), the Cochrane Library, Embase (Ovid), MEDLINE (Ovid), SPORTDiscus (EBSCOhost), and Scopus from inception to present with no date or language limitations. Two independent reviewers will screen titles, abstracts, and full texts, appraise methodological quality, and extract data from studies. Where possible, studies will be pooled in a statistical meta-analysis in addition to subgroup analyses. Where pooling is not possible, the findings will be presented in narrative format. Certainty of the evidence will be assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Review Registration: PROSPERO CRD42023360781. Competing Interests: The authors declare no conflict of interest. (Copyright © 2023 JBI.) |
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| تواريخ الأحداث: | Date Created: 20230802 Date Completed: 20240807 Latest Revision: 20240807 |
| رمز التحديث: | 20240808 |
| DOI: | 10.11124/JBIES-23-00047 |
| PMID: | 37529977 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2689-8381 |
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| DOI: | 10.11124/JBIES-23-00047 |