دورية أكاديمية
Isolation and Detection of Drug-Resistant Bacterial Pathogens in Postoperative Wound Infections at a Tertiary Care Hospital in Saudi Arabia.
| العنوان: | Isolation and Detection of Drug-Resistant Bacterial Pathogens in Postoperative Wound Infections at a Tertiary Care Hospital in Saudi Arabia. |
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| المؤلفون: | Al-Said HM; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Alghamdi A; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Ashgar SS; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Jalal NA; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Faidah HS; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Johargy AK; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Momenah AM; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Barhameen AA; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Hariri SH; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Bantun F; Department of Microbiology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Althobiany E; Department of Medical Microbiology, Al-Noor Specialist Hospital, Makkah, Saudi Arabia., Khidir EB; Department of Laboratory Medicine, Faculty of Applied Medical Science, Umm Al-Qura University, Makkah, Saudi Arabia. |
| المصدر: | Saudi journal of medicine & medical sciences [Saudi J Med Med Sci] 2023 Jul-Sep; Vol. 11 (3), pp. 229-234. Date of Electronic Publication: 2023 Jul 15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wolters Kluwer - Medknow Publications Country of Publication: India NLM ID: 101675905 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2321-4856 (Electronic) Linking ISSN: 23214856 NLM ISO Abbreviation: Saudi J Med Med Sci Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Mumbai : Wolters Kluwer - Medknow Publications, [2013]- |
| مستخلص: | Background: Surgical site infections (SSIs), especially when caused by multidrug-resistant (MDR) bacteria, are a major healthcare concern worldwide. For optimal treatment and prevention of antimicrobial resistance, it is important for clinicians to be aware of local drug-resistant bacterial pathogens that cause SSIs. Objective: To determine the frequency patterns of drug-resistant bacterial strains causing SSIs at a tertiary care hospital in Saudi Arabia. Methods: This retrospective study was conducted at the Microbiology laboratory of Al-Noor Specialist Hospital, Makkah, Saudi Arabia, and included wound swab samples from all cases of SSI between January 01, 2017, and December 31, 2021. The swabs were processed for the identification of bacterial strains and their resistance pattern to antibiotics according to the Clinical and Laboratory Standards Institute. Results: A total of 5409 wound swabs were analyzed, of which 3604 samples (66.6%) were from male. Most samples were from the Department of Surgery (43.3%). A total of 14 bacterial strains were isolated, of which 9 were Gram-negative bacteria. The most common isolates were Klebsiella pneumoniae , followed by Pseudomonas aeruginosa , Escherichia coli , Acinetobacter baumannii , methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococci (VRE), and vancomycin-resistant S. aureus (VRSA). In terms of MDR in 2021, the highest rate of carbapenem-resistance was in A. baumannii (97%). MDR was as follows: A. baumannii , 97%; K. pneumoniae , 81%; E. coli , 71%; MRSA, 60%; P. aeruginosa , 33%; VRE, 22%; and VRSA, 2%. Conclusion: This study showed that in the city of Makkah, Saudi Arabia, the rates of MDR bacteria are high, with the majority being Gram-negative. Competing Interests: There are no conflicts of interest. (Copyright: © 2023 Saudi Journal of Medicine & Medical Sciences.) |
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| فهرسة مساهمة: | Keywords: Antibacterial drug resistance; Gram-negative bacteria; MRSA; Saudi Arabia; colistin; health care associated infections; surgical site infections |
| تواريخ الأحداث: | Date Created: 20230803 Latest Revision: 20231031 |
| رمز التحديث: | 20231101 |
| مُعرف محوري في PubMed: | PMC10393095 |
| DOI: | 10.4103/sjmms.sjmms_405_22 |
| PMID: | 37533663 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2321-4856 |
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| DOI: | 10.4103/sjmms.sjmms_405_22 |