دورية أكاديمية
أعرض في EDS

Ambulatory blood pressure monitoring in pheochromocytoma - paraganglioma: A single center experience.

التفاصيل البيبلوغرافية
العنوان: Ambulatory blood pressure monitoring in pheochromocytoma - paraganglioma: A single center experience.
المؤلفون: Memon SS; Department of Endocrinology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., Srivastava P; Department of Endocrinology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., Karlekar M; Department of Endocrinology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., Thakkar H; Department of Radiology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., Bandgar T; Department of Endocrinology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
مؤلفون مشاركون: KEM Pheochromocytoma Investigators
المصدر: Journal of postgraduate medicine [J Postgrad Med] 2024 Apr 01; Vol. 70 (2), pp. 84-90. Date of Electronic Publication: 2023 Aug 04.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Medknow Publications Country of Publication: India NLM ID: 2985196R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0972-2823 (Electronic) Linking ISSN: 00223859 NLM ISO Abbreviation: J Postgrad Med Subsets: MEDLINE
أسماء مطبوعة: Publication: Mumbai : Medknow Publications
Original Publication: Bombay, India.
مواضيع طبية MeSH: Pheochromocytoma* , Blood Pressure Monitoring, Ambulatory* , Adrenal Gland Neoplasms* , Paraganglioma*/diagnosis , Hypertension*/drug therapy , Hypertension*/diagnosis , Blood Pressure*, Humans ; Male ; Female ; Adult ; Retrospective Studies ; Middle Aged ; India
مستخلص: Context/aims: Pheochromocytoma and paraganglioma (PPGL) are rare tumors, and data on ambulatory blood pressure monitoring (ABPM) in these patients and the effect of blocking on ABPM parameters is limited. We aimed to describe ABPM parameters in a cohort of PPGL at our center in western India.
Methods: Retrospective study of patients with PPGL whose ABPM data was available. Demographic details, secretory status, and ABPM data were retrieved. Coefficient of variability (CV) was calculated as standard deviation/mean in percentage.
Results: In the 39 included patients, mean age at presentation was 39.3 ± 14.2 yr; 20 (51.3%) were males, 25 (64.1%) hypertensive, and mean tumor diameter was 5.3 cm. In 18 patients whose baseline ABPM was done without medications, those with nocturnal blood pressure dipping (6/18, 33%) had higher serum metanephrines (median 313.2 vs. 34.7 pg/ml, P = 0.028). Despite normal office blood pressure (BP), 8.9% of systolic BP readings were >140 mmHg, and 1.2% were >160 mmHg. Among 29 patients with both pre and post-block ABPM, mean BP (systolic 121.6 vs. 132.5 mmHg, P = 0.014; diastolic 68.9 vs. 76.4 mmHg, P = 0.005) and percentage of BP readings above 140 mmHg (median 9.4% vs. 24.4%, P = 0.016) were significantly lowered after the preoperative blockade in hypertensive ( n = 19) patients, whereas CV was similar. The post-blockade ABPM characteristics were similar in patients blocked with amlodipine or prazosin.
Conclusion: ABPM provides additional information about BP characteristics in PPGL. The preoperative blocking decreases the magnitude of BP excursions but does not affect BP variability.
(Copyright © 2023 Copyright: © 2023 Journal of Postgraduate Medicine.)
References: J Clin Hypertens (Greenwich). 2006 Sep;8(9):642-8. (PMID: 16957426)
J Clin Endocrinol Metab. 2021 Jul 13;106(8):e2907-e2918. (PMID: 33839787)
Hypertension. 2020 Jun;75(6):1334-1357. (PMID: 32370572)
J Clin Endocrinol Metab. 2014 Jun;99(6):1915-42. (PMID: 24893135)
J Clin Endocrinol Metab. 2019 Nov 1;104(11):5170-5180. (PMID: 31009053)
J Hypertens. 2018 Oct;36(10):1953-2041. (PMID: 30234752)
J Hypertens. 2013 Sep;31(9):1731-68. (PMID: 24029863)
J Hypertens. 1988 Jan;6(1):9-15. (PMID: 3351298)
Arq Bras Cardiol. 2016 Jun;106(6):528-37. (PMID: 27168473)
Lancet Neurol. 2010 May;9(5):469-80. (PMID: 20227347)
Blood Press Monit. 2015 Oct;20(5):241-4. (PMID: 26049213)
Am J Hypertens. 1994 Jun;7(6):492-7. (PMID: 7917145)
Medicine (Baltimore). 2019 Jul;98(28):e16347. (PMID: 31305424)
J Clin Hypertens (Greenwich). 2019 Sep;21(9):1250-1283. (PMID: 31532913)
J Hypertens. 2005 Nov;23(11):2033-9. (PMID: 16208146)
Blood Press. 1993 Mar;2(1):35-9. (PMID: 8193728)
Cancers (Basel). 2019 May 12;11(5):. (PMID: 31083609)
J Hum Hypertens. 1990 Aug;4(4):397-9. (PMID: 2258883)
تواريخ الأحداث: Date Created: 20230809 Date Completed: 20240429 Latest Revision: 20240609
رمز التحديث: 20240609
مُعرف محوري في PubMed: PMC11160991
DOI: 10.4103/jpgm.jpgm_208_23
PMID: 37555422
قاعدة البيانات: MEDLINE
الوصف
تدمد:0972-2823
DOI:10.4103/jpgm.jpgm_208_23