دورية أكاديمية
Minimal important difference of the 6-minute walk test after allogenic hematopoietic stem cell transplantation.
| العنوان: | Minimal important difference of the 6-minute walk test after allogenic hematopoietic stem cell transplantation. |
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| المؤلفون: | Murao M; Rehabilitation Unit, Kyoto University Hospital, Kyoto, Japan., Kondo T; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan., Hamada R; Rehabilitation Unit, Kyoto University Hospital, Kyoto, Japan., Miyasaka J; Rehabilitation Unit, Kyoto University Hospital, Kyoto, Japan., Matsushita M; Rehabilitation Unit, Kyoto University Hospital, Kyoto, Japan., Otagaki A; Rehabilitation Unit, Kyoto University Hospital, Kyoto, Japan., Kajimoto T; Rehabilitation Unit, Kyoto University Hospital, Kyoto, Japan., Arai Y; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Clinical Laboratory Medicine, Faculty of Medicine, Kyoto University, Kyoto, Japan., Kanda J; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Nankaku M; Rehabilitation Unit, Kyoto University Hospital, Kyoto, Japan., Ikeguchi R; Rehabilitation Unit, Kyoto University Hospital, Kyoto, Japan., Takaori-Kondo A; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Matsuda S; Rehabilitation Unit, Kyoto University Hospital, Kyoto, Japan. |
| المصدر: | Disability and rehabilitation [Disabil Rehabil] 2024 Jul; Vol. 46 (15), pp. 3449-3456. Date of Electronic Publication: 2023 Aug 13. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 9207179 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-5165 (Electronic) Linking ISSN: 09638288 NLM ISO Abbreviation: Disabil Rehabil Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2015- : Abingdon, Oxford : Taylor & Francis Original Publication: London ; Washington, DC : Taylor & Francis, c1992- |
| مواضيع طبية MeSH: | Hematopoietic Stem Cell Transplantation* , Walk Test* , Quality of Life* , ROC Curve*, Humans ; Male ; Female ; Middle Aged ; Adult ; Transplantation, Homologous ; Minimal Clinically Important Difference ; Surveys and Questionnaires ; Aged |
| مستخلص: | Purpose: The 6-min walk test (6MWT) of allogenic hematopoietic stem cell transplantation (allo-HSCT) recipients has been gaining attention; however, minimal differences have not been reported. This study aimed to determine the minimal important difference (MID) in the 6MWT among hospitalized patients with allo-HSCT. Materials and Methods: The MID of the 6MWT was calculated using three different methodologies based on an anchor-based method; basic anchor-based methods, linear regression analysis, and receiver operating characteristic (ROC) curve analysis. The decrease in the score of Question 2 of the European Organization for Research and Treatment of Cancer Quality of life questionnaire core-30 was included as an anchor question for calculating the MID. Both actual and percentage changes in 6MWT values from baseline and at discharge were used in the MID calculations. In the actual and percentage change of the 6MWT, the one with the larger the area under the curve in the ROC curve was recommended as the MID. Results: Among the three methods using actual values, the largest MID of the 6MWT was -37.5 m (sensitivity: 54%, specificity: 88%). Conclusion: More careful follow-up after discharge is necessary for allo-HSCT patients who show a reduction of 37.5 m or more in the acute illness phase. |
| فهرسة مساهمة: | Keywords: 6-minute walk test; Allogeneic hematopoietic stem cell transplantation; exercise tolerance; minimal important difference; the European organization for research and treatment of cancer quality of life questionnaire core-30 Local Abstract: [plain-language-summary] Advancements in allogeneic hematopoietic stem cell transplantation have improved the survival rates of individuals with malignant hematological disorders, and efforts should now be focused on enhancing their physical function and quality of life.There is a problem that the physical performance of the patients is reduced by the side effects of treatment.More careful follow-up after discharge is necessary for allo-HSCT patients who show a reduction of 37.5 m or more in the acute illness phase. |
| تواريخ الأحداث: | Date Created: 20230814 Date Completed: 20240713 Latest Revision: 20240713 |
| رمز التحديث: | 20240713 |
| DOI: | 10.1080/09638288.2023.2246013 |
| PMID: | 37574839 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1464-5165 |
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| DOI: | 10.1080/09638288.2023.2246013 |