دورية أكاديمية
أعرض في EDS

Paternal age and perinatal outcomes: an observational study.

التفاصيل البيبلوغرافية
العنوان: Paternal age and perinatal outcomes: an observational study.
المؤلفون: Xholli A; Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale San Martino, Genoa, Italy., Londero AP; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Infant Health, University of Genoa, Genova (GE), Italy.; Obstetrics and Gynecology Unit, IRCCS Istituto Giannina Gaslini, Genova (GE), Italy., Magnetti E; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Infant Health, University of Genoa, Genova (GE), Italy., Vadrucci S; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Infant Health, University of Genoa, Genova (GE), Italy., Neri I; Obstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy., Marcantognini G; School of Midwifery, Department of, Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy., Tramontano AL; Obstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy., Monari F; Obstetrics and Gynecology Unit, Mother-Infant and Adult Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy., Cagnacci A; Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale San Martino, Genoa, Italy.; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Infant Health, University of Genoa, Genova (GE), Italy.
المصدر: Journal of perinatal medicine [J Perinat Med] 2023 Aug 21; Vol. 52 (1), pp. 58-64. Date of Electronic Publication: 2023 Aug 21 (Print Publication: 2024).
نوع المنشور: Observational Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: Walter De Gruyter Country of Publication: Germany NLM ID: 0361031 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1619-3997 (Electronic) Linking ISSN: 03005577 NLM ISO Abbreviation: J Perinat Med Subsets: MEDLINE
أسماء مطبوعة: Publication: Berlin : Walter De Gruyter
Original Publication: Berlin, New York, Walter de Gruyter.
مواضيع طبية MeSH: Paternal Age* , Placenta*, Infant, Newborn ; Pregnancy ; Female ; Male ; Humans ; Semen ; Parturition ; Maternal Age ; Pregnancy Outcome/epidemiology ; Retrospective Studies
مستخلص: Objectives: The study's primary aim was to examine the relationship between paternal age and perinatal outcomes.
Methods: This study used data from two hospital birth registries to examine the association between paternal age and adverse perinatal outcomes. The sample included all live singleton births between 2010 and 2022. The primary exposure was paternal age, and the following perinatal outcomes were considered: mode of conception, mode of delivery, pregnancy complications, and neonatal outcomes.
Results: A total of 15,232 pregnant women were considered. Maternal and paternal ages were 31.9 ± 5.3 and 36.5 ± 6.5 years, respectively. Independent of maternal, paternal age was associated with lower odds of spontaneous conceptions (OR 0.930, 95 % CI 0.968/0.993; p=0.003) and higher odds of intracytoplasmatic sperm injection (OR 1.054, 95 % CI 1.045/1.062; p=0.0001), respectively. In contrast to maternal age, paternal age decreased the odds of any (OR 0.922, 95 % CI 0.985/0.999; p=0.032) and urgent/emergent (OR 0.984, 95 % CI 0.975/0.993; p=0.0001) cesarean delivery. Paternal age did not affect the gestation length, placental or neonatal weight, blood loss during delivery, and neonatal 5th-minute Apgar score.
Conclusions: Paternal age is associated with perinatal outcomes. These findings suggest that advanced paternal age may have implications for reproductive counseling and prenatal care.
(© 2023 Walter de Gruyter GmbH, Berlin/Boston.)
References: Nilsen, ABV, Waldenström, U, Rasmussen, S, Hjelmstedt, A, Schytt, E. Characteristics of first-time fathers of advanced age: a Norwegian population-based study. BMC Pregnancy Childbirth 2013;13:29. https://doi.org/10.1186/1471-2393-13-29 . (PMID: 10.1186/1471-2393-13-29)
Khandwala, YS, Zhang, CA, Lu, Y, Eisenberg, ML. The age of fathers in the USA is rising: an analysis of 168 867 480 births from 1972 to 2015. Hum Reprod 2017;32:2110–16. https://doi.org/10.1093/humrep/dex267 . (PMID: 10.1093/humrep/dex267)
Sartorius, GA, Nieschlag, E. Paternal age and reproduction. Hum Reprod Update 2010;16:65–79. https://doi.org/10.1093/humupd/dmp027 . (PMID: 10.1093/humupd/dmp027)
Joffe, M, Li, Z. Male and female factors in fertility. Am J Epidemiol 1994;140:921–9. https://doi.org/10.1093/oxfordjournals.aje.a117180 . (PMID: 10.1093/oxfordjournals.aje.a117180)
Belloc, S, Cohen-Bacrie, P, Benkhalifa, M, Cohen-Bacrie, M, De Mouzon, J, Hazout, A, et al.. Effect of maternal and paternal age on pregnancy and miscarriage rates after intrauterine insemination. Reprod Biomed Online 2008;17:392–7. https://doi.org/10.1016/s1472-6483(10)60223-4 . (PMID: 10.1016/s1472-6483(10)60223-4)
Kortekaas, JC, Kazemier, BM, Keulen, JKJ, Bruinsma, A, Mol, BW, Vandenbussche, F, et al.. Risk of adverse pregnancy outcomes of late- and postterm pregnancies in advanced maternal age: a national cohort study. Acta Obstet Gynecol Scand 2020;99:1022–30. https://doi.org/10.1111/aogs.13828 . (PMID: 10.1111/aogs.13828)
Londero, AP, Rossetti, E, Pittini, C, Cagnacci, A, Driul, L. Maternal age and the risk of adverse pregnancy outcomes: a retrospective cohort study. BMC Pregnancy Childbirth 2019;19:261. https://doi.org/10.1186/s12884-019-2400-x . (PMID: 10.1186/s12884-019-2400-x)
Kendrick, J, Sharma, S, Holmen, J, Palit, S, Nuccio, E, Chonchol, M. Kidney disease and maternal and fetal outcomes in pregnancy. Am J Kidney Dis 2015;66:55–9. https://doi.org/10.1053/j.ajkd.2014.11.019 . (PMID: 10.1053/j.ajkd.2014.11.019)
Vigil-De Gracia, P, Montufar-Rueda, C, Smith, A. Pregnancy and severe chronic hypertension: maternal outcome. Hypertens Pregnancy 2004;23:285–93. https://doi.org/10.1081/prg-200030315 . (PMID: 10.1081/prg-200030315)
Li, J, Qiu, J, Lv, L, Mao, B, Huang, L, Yang, T, et al.. Paternal factors and adverse birth outcomes in Lanzhou, China. BMC Pregnancy Childbirth 2021;21:19. https://doi.org/10.1186/s12884-020-03492-9 . (PMID: 10.1186/s12884-020-03492-9)
Bamanikar, AA, Shah, S, Aboudi, D, Mikkilineni, S, Giblin, C, Lavan, T, et al.. Impact of paternal presence and parental social-demographic characteristics on birth outcomes. J Perinat Med 2021;49:1154–62. https://doi.org/10.1515/jpm-2021-0078 . (PMID: 10.1515/jpm-2021-0078)
Thompson, JA. The risks of advancing parental age on neonatal morbidity and mortality are U-or J-shaped for both maternal and paternal ages. BMC Pediatr 2020;20:453. https://doi.org/10.1186/s12887-020-02341-0 . (PMID: 10.1186/s12887-020-02341-0)
Hanson, BM, Kim, JG, Osman, EK, Tiegs, AW, Lathi, RB, Cheng, PJ, et al.. Impact of paternal age on embryology and pregnancy outcomes in the setting of a euploid single-embryo transfer with ejaculated sperm: retrospective cohort study. F S Rep 2020;1:99–105. https://doi.org/10.1016/j.xfre.2020.06.004 . (PMID: 10.1016/j.xfre.2020.06.004)
Collins, JW, Rankin, KM, David, RJ. Paternal lifelong socioeconomic position and low birth weight rates: relevance to the african-American women’s birth outcome disadvantage. Matern Child Health J 2016;20:1759–66. https://doi.org/10.1007/s10995-016-1981-5 . (PMID: 10.1007/s10995-016-1981-5)
Hurley, EG, DeFranco, EA. Influence of paternal age on perinatal outcomes. Am J Obstet Gynecol 2017;217:566.e1–6. https://doi.org/10.1016/j.ajog.2017.07.034 . (PMID: 10.1016/j.ajog.2017.07.034)
Meng, Y, Groth, SW. Fathers count: the impact of paternal risk factors on birth outcomes. Matern Child Health J 2018;22:401–8. https://doi.org/10.1007/s10995-017-2407-8 . (PMID: 10.1007/s10995-017-2407-8)
Shah, PS. Knowledge synthesis group on determinants of preterm/low birthweight births. Paternal factors and low birthweight, preterm, and small for gestational age births: a systematic review. Am J Obstet Gynecol 2010;202:103–23. https://doi.org/10.1016/j.ajog.2009.08.026 . (PMID: 10.1016/j.ajog.2009.08.026)
Mao, Y, Zhang, C, Wang, Y, Meng, Y, Chen, L, Dennis, CL, et al.. Association between paternal age and birth weight in preterm and full-term birth: a retrospective study. Front Endocrinol 2021;12:706369. https://doi.org/10.3389/fendo.2021.706369 . (PMID: 10.3389/fendo.2021.706369)
Tang, CH, Wu, MP, Liu, JT, Lin, HC, Hsu, CC. Delayed parenthood and the risk of cesarean delivery–is paternal age an independent risk factor? Birth 2006;33:18–26. https://doi.org/10.1111/j.0730-7659.2006.00070.x . (PMID: 10.1111/j.0730-7659.2006.00070.x)
Bertino, E, Spada, E, Occhi, L, Coscia, A, Giuliani, F, Gagliardi, L, et al.. Neonatal anthropometric charts: the Italian neonatal study compared with other European studies. J Pediatr Gastroenterol Nutr 2010;51:353–61. https://doi.org/10.1097/mpg.0b013e3181da213e . (PMID: 10.1097/mpg.0b013e3181da213e)
Bekedam, DJ, Engelsbel, S, Mol, jBW, Buitendijk, SE, van der Pal-de Bruin, KM. Male predominance in fetal distress during labor. Am J Obstet Gynecol 2002;187:1605–7. https://doi.org/10.1067/mob.2002.127379 . (PMID: 10.1067/mob.2002.127379)
Nagy, E, Orvos, H, Bakki, J, Pal, A. Sex-differences in Apgar scores for full-term neonates. Acta Paediatr 2009;98:898–900. https://doi.org/10.1111/j.1651-2227.2009.01238.x . (PMID: 10.1111/j.1651-2227.2009.01238.x)
Monier, I, Ego, A, Benachi, A, Hocquette, A, Blondel, B, Goffinet, F, et al.. Unisex vs sex-specific estimated fetal weight charts for fetal growth monitoring: a population-based study. Am J Obstet Gynecol MFM 2022;4:100527. https://doi.org/10.1016/j.ajogmf.2021.100527 . (PMID: 10.1016/j.ajogmf.2021.100527)
Faro, R, Santolaya-Forgas, J, Canterino, JC, Oyelese, Y, Ananth, CV. Paternal age and risk for cesarean delivery. J Matern Fetal Neonatal Med 2012;25:2713–16. https://doi.org/10.3109/14767058.2012.703727 . (PMID: 10.3109/14767058.2012.703727)
Khandwala, YS, Baker, VL, Shaw, GM, Stevenson, DK, Lu, Y, Eisenberg, ML. Association of paternal age with perinatal outcomes between 2007 and 2016 in the United States: population based cohort study. BMJ 2018;363:k4372. https://doi.org/10.1136/bmj.k4372 . (PMID: 10.1136/bmj.k4372)
Belloc, S, Hazout, A, Zini, A, Merviel, P, Cabry, R, Chahine, H, et al.. How to overcome male infertility after 40: influence of paternal age on fertility. Maturitas 2014;78:22–9. https://doi.org/10.1016/j.maturitas.2014.02.011 . (PMID: 10.1016/j.maturitas.2014.02.011)
Johnson, SL, Dunleavy, J, Gemmell, NJ, Nakagawa, S. Consistent age-dependent declines in human semen quality: a systematic review and meta-analysis. Ageing Res Rev 2015;19:22–33. https://doi.org/10.1016/j.arr.2014.10.007 . (PMID: 10.1016/j.arr.2014.10.007)
Bray, I, Gunnell, D, Davey Smith, G. Advanced paternal age: how old is too old? J Epidemiol Community Health 2006;60:851–3. https://doi.org/10.1136/jech.2005.045179 . (PMID: 10.1136/jech.2005.045179)
du Fossé, NA, van der Hoorn, MLP, van Lith, JMM, le Cessie, S, Lashley, EELO. Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis. Hum Reprod Update 2020;26:650–69. https://doi.org/10.1093/humupd/dmaa010 . (PMID: 10.1093/humupd/dmaa010)
Borgstrøm, MB, Grøndahl, ML, Klausen, TW, Danielsen, AK, Thomsen, T, Bentin-Ley, U, et al.. Is paternal age associated with transfer day, developmental stage, morphology, and initial hCG-rise of the competent blastocyst leading to live birth? A multicenter cohort study. PLoS One 2022;17:e0270664. https://doi.org/10.1371/journal.pone.0270664 . (PMID: 10.1371/journal.pone.0270664)
Yu, T, Chen, TS, Liang, FW, Kuo, PL. Does sex matter? Association of fetal sex and parental age with pregnancy outcomes in Taiwan: a cohort study. BMC Pregnancy Childbirth 2020;20:348. https://doi.org/10.1186/s12884-020-03039-y . (PMID: 10.1186/s12884-020-03039-y)
Londero, AP, Orsaria, M, Parisi, N, Tassi, A, Pittini, C, Driul, L, et al.. In vitro fertilization is associated with placental accelerated villous maturation. Int J Clin Exp Pathol 2021;14:734–40.
Marmot, M, Allen, J, Bell, R, Bloomer, E, Goldblatt, P. Consortium for the European review of social determinants of health and the health divide. WHO European review of social determinants of health and the health divide. Lancet 2012;380:1011–29. https://doi.org/10.1016/s0140-6736(12)61228-8 . (PMID: 10.1016/s0140-6736(12)61228-8)
Davis, EP, Narayan, AJ. Pregnancy as a period of risk, adaptation, and resilience for mothers and infants. Dev Psychopathol 2020;32:1625–39. https://doi.org/10.1017/s0954579420001121 . (PMID: 10.1017/s0954579420001121)
Lee, SJ, Sanchez, DT, Grogan-Kaylor, A, Lee, JY, Albuja, A. Father early engagement behaviors and infant low birth weight. Matern Child Health J 2018;22:1407–17. https://doi.org/10.1007/s10995-018-2521-2 . (PMID: 10.1007/s10995-018-2521-2)
فهرسة مساهمة: Keywords: fertility; maternal age; mode of delivery; paternal age; perinatal outcomes
تواريخ الأحداث: Date Created: 20230819 Date Completed: 20240112 Latest Revision: 20240112
رمز التحديث: 20240112
DOI: 10.1515/jpm-2023-0205
PMID: 37596820
قاعدة البيانات: MEDLINE
الوصف
تدمد:1619-3997
DOI:10.1515/jpm-2023-0205