التفاصيل البيبلوغرافية
| العنوان: |
Two new 30-norfriedelane triterpenes from Caloncoba glauca (P. Beauv.) Gilg (Achariaceae). |
| المؤلفون: |
Ndoumbe Tamba C; Chemistry Laboratory, Department of Chemistry, University of Douala, Douala, Cameroon., Tsopgni WDT; Chemistry Laboratory, Department of Chemistry, University of Douala, Douala, Cameroon., Fotso BSH; Department of Organic Chemistry, University of Yaounde 1, Yaounde, Cameroon., Longue Ekon JP; Chemistry Laboratory, Department of Chemistry, University of Douala, Douala, Cameroon., Foundikou Nsangou M; Chemistry Laboratory, Department of Chemistry, University of Douala, Douala, Cameroon., Ngo Nyobe JC; Department of Pharmaceutical Sciences, University of Douala, Douala, Cameroon., Sewald N; Organic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Bielefeld, Germany., Ndom JC; Chemistry Laboratory, Department of Chemistry, University of Douala, Douala, Cameroon. |
| المصدر: |
Natural product research [Nat Prod Res] 2023 Aug 21, pp. 1-11. Date of Electronic Publication: 2023 Aug 21. |
| Publication Model: |
Ahead of Print |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مستخلص: |
The chemical investigation of the methanolic root extract of Caloncoba glauca (P. Beauv.) Gilg exhibited two new 30-norfriedelane triterpenes, glaucalactones A and B ( 1-2 ), together with eight known compounds, caloncobalactone ( 3 ), friedelin ( 4 ), friedelanol (5 ), 3-oxo-friedelan-28-oic acid ( 6 ), stigmasterol ( 7 ), β -sitosterol ( 8 ), β -sitosterol-3- O - β -D-glucopyranoside ( 9 ) and pentacosanoic acid ( 10 ). The structures of the isolates were elucidated by extensive spectroscopic and spectrometric analyses (1D and 2D NMR, ESI-MS) and by comparison with previously reported data. All the compounds were tested for their antioxidant, antifungal and antibacterial activities. Compound 1 displayed weak antibacterial effect with MIC value of 125 μg/mL against Staphylococcus aureus and Escherishia coli . Compound 6 exhibited moderated antifungal activity against Candida krusei with MIC value of 62.5 μg/mL. All the isolates were found to be inactive as antioxidants in the DPPH, ABTS and FRAP assays. |
| فهرسة مساهمة: |
Keywords: 30-norfriedelane; Caloncoba glauca; achariaceae; antibacterial activity; antifungal activity; antioxidant potential |
| تواريخ الأحداث: |
Date Created: 20230821 Latest Revision: 20230821 |
| رمز التحديث: |
20231215 |
| DOI: |
10.1080/14786419.2023.2248351 |
| PMID: |
37602437 |
| قاعدة البيانات: |
MEDLINE |
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