التفاصيل البيبلوغرافية
| العنوان: |
Arbovirus surveillance in pregnant women in north-central Nigeria, 2019-2022. |
| المؤلفون: |
Ogwuche J, Chang CA, Ige O, Sagay AS, Chaplin B, Kahansim ML, Paul M, Elujoba M, Imade G, Kweashi G, Dai YC, Hsieh SC, Wang WK, Hamel DJ, Kanki PJ |
| المصدر: |
MedRxiv : the preprint server for health sciences [medRxiv] 2023 Aug 08. Date of Electronic Publication: 2023 Aug 08. |
| نوع المنشور: |
Preprint |
| اللغة: |
English |
| بيانات الدورية: |
Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE |
| مستخلص: |
The adverse impact of Zika (ZIKV), dengue (DENV), and chikungunya (CHIKV) virus infection in pregnancy has been recognized in Latin America and Asia but is not well studied in Africa. In Nigeria, we screened 1006 pregnant women for ZIKV, DENV and CHIKV IgM/IgG by rapid test (2019-2022). Women with acute infection were recruited for prospective study and infants were examined for any abnormalities from delivery through six months. A subset of rapid test-reactive samples were confirmed using virus-specific ELISAs and neutralization assays. Prevalence of acute infection (IgM+) was 3.8%, 9.9% and 11.8% for ZIKV, DENV and CHIKV, respectively; co-infections represented 24.5% of all infections. Prevalence in asymptomatic women was twice the level of symptomatic infection. We found a significant association between acute maternal ZIKV/DENV/CHIKV infection and any gross abnormal birth outcome (p=0.014). Further prospective studies will contribute to our understanding of the clinical significance of these endemic arboviruses in Africa. |
| التعليقات: |
Update in: J Clin Virol. 2023 Nov 3;169:105616. (PMID: 37944259) |
| تواريخ الأحداث: |
Date Created: 20230823 Latest Revision: 20231207 |
| رمز التحديث: |
20231215 |
| مُعرف محوري في PubMed: |
PMC10441490 |
| DOI: |
10.1101/2023.08.04.23293671 |
| PMID: |
37609234 |
| قاعدة البيانات: |
MEDLINE |
