دورية أكاديمية
Visually enhanced vestibulo-ocular reflex gain in patients with vestibular disease.
| العنوان: | Visually enhanced vestibulo-ocular reflex gain in patients with vestibular disease. |
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| المؤلفون: | Kim EK; Department of Otolaryngology-Head and Neck Surgery University of California, San Francisco San Francisco California USA., Sienko N; Department of Otolaryngology-Head and Neck Surgery University of California, San Francisco San Francisco California USA., Gardi A; Department of Otolaryngology-Head and Neck Surgery University of California, San Francisco San Francisco California USA., Krauter R; Department of Otolaryngology-Head and Neck Surgery University of California, San Francisco San Francisco California USA.; Department of Family Health Care Nursing, School of Nursing University of California, San Francisco San Francisco California USA., Pasquesi L; Department of Otolaryngology-Head and Neck Surgery University of California, San Francisco San Francisco California USA., Sharon JD; Department of Otolaryngology-Head and Neck Surgery University of California, San Francisco San Francisco California USA. |
| المصدر: | Laryngoscope investigative otolaryngology [Laryngoscope Investig Otolaryngol] 2023 Jul 12; Vol. 8 (4), pp. 1061-1067. Date of Electronic Publication: 2023 Jul 12 (Print Publication: 2023). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 101684963 Publication Model: eCollection Cited Medium: Print ISSN: 2378-8038 (Print) Linking ISSN: 23788038 NLM ISO Abbreviation: Laryngoscope Investig Otolaryngol Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Hoboken, NJ] : Wiley, [2016]- |
| مستخلص: | Objective: Vestibular migraine (VM) is a diagnostic challenge. Visually enhanced vestibulo-ocular reflex (VVOR) gain, a measure of the visual-vestibular interaction, has been proposed as a tool for diagnosing VM. This study seeks to evaluate VVOR gain's diagnostic capability to predict VM and to compare the phenotypes of vestibular patients with elevated versus normal/low VVOR gain. Methods: A retrospective review of consecutive adult patients at a dizziness clinic from October 2016 and December 2020 was conducted. VVOR gain's diagnostic performance was assessed with the area under the receiver operating characteristic (AUROC) analysis. Demographic factors and clinical presentations were compared between vestibular patients with elevated versus normal/low VVOR gain. Results: One hundred forty patients (70 with VM) were analyzed. VVOR gain was elevated in 68.6% of patients with VM, compared to 52.9% of patients without VM ( p = .057). The AUROC of VVOR gain was 0.5902 (95% confidence interval: 0.4958-0.6846). Vestibular patients with elevated VVOR gain were younger than those with normal/low VVOR gain (mean age 50 vs. 62, p < .0001). A higher proportion of subjects with elevated VVOR gain had symptoms triggered by certain foods (17.6% vs. 5.5%, p = .040) and experienced sound sensitivity (34.1% vs. 18.2%, p = .040) and motion sensitivity (23.5% vs. 9.1%, p = .041). A greater proportion of VM patients with elevated VVOR gain were triggered by certain foods (27.1% vs. 0%, p = .006). Conclusion: VVOR gain alone has limited ability to discriminate VM from other vestibular conditions and must be interpreted carefully. VVOR gain elevation may be associated with food triggers and motion and sound sensitivity. Level of Evidence: IV. Competing Interests: Jeffrey D. Sharon receives research support from Advanced Bionics and Eli Lilly and is a paid consultant for Spiral Therapeutics. All other authors have no conflicts of interest or sources of funding to disclose. (© 2023 The Authors. Laryngoscope Investigative Otolaryngology published by Wiley Periodicals LLC on behalf of The Triological Society.) |
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| فهرسة مساهمة: | Keywords: VVOR; vestibular migraine; visually enhanced vestibulo‐ocular reflex |
| تواريخ الأحداث: | Date Created: 20230825 Latest Revision: 20230826 |
| رمز التحديث: | 20230826 |
| مُعرف محوري في PubMed: | PMC10446303 |
| DOI: | 10.1002/lio2.1106 |
| PMID: | 37621269 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2378-8038 |
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| DOI: | 10.1002/lio2.1106 |