دورية أكاديمية
أعرض في EDS

Attenuated Total Reflection Fourier-Transform Infrared Spectral Discrimination in Human Tissue of Oesophageal Transformation to Adenocarcinoma.

التفاصيل البيبلوغرافية
العنوان: Attenuated Total Reflection Fourier-Transform Infrared Spectral Discrimination in Human Tissue of Oesophageal Transformation to Adenocarcinoma.
المؤلفون: Maitra I; School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK., Morais CLM; Institute of Chemistry, Biological Chemistry and Chemometrics, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.; Center for Education, Science and Technology of the Inhamuns Region, State University of Ceará, Tauá 63660-000, Brazil., Lima KMG; Institute of Chemistry, Biological Chemistry and Chemometrics, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil., Ashton KM; Lancashire Teaching Hospitals NHS Foundation Trust, Royal Preston Hospital, Preston PR2 9HT, UK., Bury D; Department of Cellular Pathology, Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool FY3 8NR, UK., Date RS; Lancashire Teaching Hospitals NHS Foundation Trust, Royal Preston Hospital, Preston PR2 9HT, UK., Martin FL; Department of Cellular Pathology, Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool FY3 8NR, UK.
المصدر: Journal of personalized medicine [J Pers Med] 2023 Aug 20; Vol. 13 (8). Date of Electronic Publication: 2023 Aug 20.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101602269 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4426 (Print) Linking ISSN: 20754426 NLM ISO Abbreviation: J Pers Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2011-
مستخلص: This study presents ATR-FTIR (attenuated total reflectance Fourier-transform infrared) spectral analysis of ex vivo oesophageal tissue including all classifications to oesophageal adenocarcinoma (OAC). The article adds further validation to previous human tissue studies identifying the potential for ATR-FTIR spectroscopy in differentiating among all classes of oesophageal transformation to OAC. Tissue spectral analysis used principal component analysis quadratic discriminant analysis (PCA-QDA), successive projection algorithm quadratic discriminant analysis (SPA-QDA), and genetic algorithm quadratic discriminant analysis (GA-QDA) algorithms for variable selection and classification. The variables selected by SPA-QDA and GA-QDA discriminated tissue samples from Barrett's oesophagus (BO) to OAC with 100% accuracy on the basis of unique spectral "fingerprints" of their biochemical composition. Accuracy test results including sensitivity and specificity were determined. The best results were obtained with PCA-QDA, where tissues ranging from normal to OAC were correctly classified with 90.9% overall accuracy (71.4-100% sensitivity and 89.5-100% specificity), including the discrimination between normal and inflammatory tissue, which failed in SPA-QDA and GA-QDA. All the models revealed excellent results for distinguishing among BO, low-grade dysplasia (LGD), high-grade dysplasia (HGD), and OAC tissues (100% sensitivities and specificities). This study highlights the need for further work identifying potential biochemical markers using ATR-FTIR in tissue that could be utilised as an adjunct to histopathological diagnosis for early detection of neoplastic changes in susceptible epithelium.
References: J Clin Med. 2019 Aug 27;8(9):. (PMID: 31461884)
Lasers Surg Med. 1999;24(5):382-8. (PMID: 10406479)
Faraday Discuss. 2016 Jun 23;187:9-42. (PMID: 27075634)
Anal Chim Acta. 2019 Jul 31;1063:40-46. (PMID: 30967184)
Stem Cells Int. 2016;2016:6709714. (PMID: 27651798)
Clin J Gastroenterol. 2020 Oct;13(5):635-649. (PMID: 32495144)
Am J Gastroenterol. 2016 Jan;111(1):30-50; quiz 51. (PMID: 26526079)
Appl Spectrosc. 2018 Sep;72(1_suppl):52-84. (PMID: 30265133)
World J Gastroenterol. 2003 Sep;9(9):1897-9. (PMID: 12970871)
Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15864-9. (PMID: 17901200)
Frontline Gastroenterol. 2017 Apr;8(2):138-142. (PMID: 28839898)
Biopolymers. 2001;62(4):185-92. (PMID: 11391568)
Analyst. 2015 Apr 7;140(7):2369-75. (PMID: 25671463)
Biospectroscopy. 1998;4(1):47-53. (PMID: 9547014)
Gastrointest Endosc Clin N Am. 2009 Apr;19(2):233-42. (PMID: 19423021)
Analyst. 2009 Jun;134(6):1240-6. (PMID: 19475154)
Crit Rev Anal Chem. 2017 May 4;47(3):194-203. (PMID: 27786540)
World J Gastroenterol. 2005 Jul 7;11(25):3842-5. (PMID: 15991279)
Spectrochim Acta A Mol Biomol Spectrosc. 2020 Mar 5;228:117695. (PMID: 31753650)
Faraday Discuss. 2016 Jun 23;187:87-103. (PMID: 27048868)
Br J Cancer. 2022 May;126(8):1125-1139. (PMID: 34893761)
Appl Immunohistochem Mol Morphol. 2009 Dec;17(6):547-52. (PMID: 19786865)
Cancer Biomark. 2018;23(3):373-380. (PMID: 30248045)
World J Gastroenterol. 2017 Jan 14;23(2):286-296. (PMID: 28127202)
Sci Total Environ. 1997 Oct 1;204(3):283-7. (PMID: 9335161)
Nat Protoc. 2014 Aug;9(8):1771-91. (PMID: 24992094)
Anal Bioanal Chem. 2007 Mar;387(5):1679-89. (PMID: 17260138)
Analyst. 2017 Apr 10;142(8):1227-1234. (PMID: 27713951)
Cancers (Basel). 2020 Jun 27;12(7):. (PMID: 32605100)
Photodiagnosis Photodyn Ther. 2018 Dec;24:237-244. (PMID: 30282049)
Analyst. 2019 Dec 2;144(24):7447-7456. (PMID: 31696873)
Nat Protoc. 2019 May;14(5):1546-1577. (PMID: 30953040)
Gut. 2014 Jan;63(1):7-42. (PMID: 24165758)
Biospectroscopy. 1998;4(2):75-91. (PMID: 9557903)
Analyst. 2018 Jun 25;143(13):3156-3163. (PMID: 29878018)
Cancer Detect Prev. 2007;31(3):244-53. (PMID: 17646059)
Analyst. 2016 Jan 21;141(2):585-94. (PMID: 26090781)
Cell. 2018 Jun 14;173(7):1742-1754.e17. (PMID: 29906449)
Spectrochim Acta A Mol Biomol Spectrosc. 2021 Sep 5;258:119818. (PMID: 33957445)
فهرسة مساهمة: Keywords: ATR-FTIR; multivariate classification; oesophageal cancer; tissue
تواريخ الأحداث: Date Created: 20230825 Latest Revision: 20230829
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10455976
DOI: 10.3390/jpm13081277
PMID: 37623527
قاعدة البيانات: MEDLINE
الوصف
تدمد:2075-4426
DOI:10.3390/jpm13081277