دورية أكاديمية
أعرض في EDS

End-to-end quality assurance for stereotactic radiotherapy with Fricke-Xylenol orange-Gelatin gel dosimeter and dual-wavelength cone-beam optical CT readout.

التفاصيل البيبلوغرافية
العنوان: End-to-end quality assurance for stereotactic radiotherapy with Fricke-Xylenol orange-Gelatin gel dosimeter and dual-wavelength cone-beam optical CT readout.
المؤلفون: Rousseau A; Université Paris-Saclay, CEA, List, Laboratoire National Henri Becquerel (LNE-LNHB), Palaiseau, France. Electronic address: alice.rousseau.91@gmail.com., Stien C; Université Paris-Saclay, CEA, List, Laboratoire National Henri Becquerel (LNE-LNHB), Palaiseau, France., Gouriou J; Université Paris-Saclay, CEA, List, Laboratoire National Henri Becquerel (LNE-LNHB), Palaiseau, France., Bordy JM; Université Paris-Saclay, CEA, List, Laboratoire National Henri Becquerel (LNE-LNHB), Palaiseau, France., Boissonnat G; Université Paris-Saclay, CEA, List, Laboratoire National Henri Becquerel (LNE-LNHB), Palaiseau, France., Chabert I; Gustave Roussy, Service de Physique, Villejuif, France., Dufreneix S; Université Paris-Saclay, CEA, List, Laboratoire National Henri Becquerel (LNE-LNHB), Palaiseau, France; Institut de Cancérologie de l'Ouest, Angers, France., Blideanu V; Université Paris-Saclay, CEA, List, Laboratoire National Henri Becquerel (LNE-LNHB), Palaiseau, France.
المصدر: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) [Phys Med] 2023 Sep; Vol. 113, pp. 102656. Date of Electronic Publication: 2023 Aug 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Istituti Editoriali e Poligrafici Internazionali Country of Publication: Italy NLM ID: 9302888 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1724-191X (Electronic) Linking ISSN: 11201797 NLM ISO Abbreviation: Phys Med Subsets: MEDLINE
أسماء مطبوعة: Publication: Pisa : Istituti Editoriali e Poligrafici Internazionali
Original Publication: Lugano, Switzerland : Giardini editori S.A.,
مواضيع طبية MeSH: Gelatin* , Radiosurgery*, Humans ; Radiation Dosimeters ; Cone-Beam Computed Tomography
مستخلص: Purpose: The end-to-end (E2E) quality assurance (QA) test is a unique tool for validating the treatment chain undergone by patients in external radiotherapy. It should be conducted in three dimensions (3D) to get accurate results. This study aims to implement these tests with Fricke-Xylenol orange-Gelatin (FXG) gel dosimeter and a newly developed dual-wavelength reading method on the Vista16™ optical Computed Tomography (CT) scanner (ModusQA) for three treatment techniques in stereotactic radiotherapy, on Novalis (Varian) and CyberKnife (Accuray) linear accelerators.
Methods: The tests were performed in head phantoms. Gel measurements were compared with planned dose distributions and measured by film and ion chamber measurements by plotting isodose curves and dose profiles, and by conducting a 3D local gamma-index analysis (2%/2mm criteria).
Results: Gamma passing rates were higher than 95 %. Point dose differences between treatment planning and gel and ion chamber measurements at the isocenter were < 2.3 % for both treatments delivered on the Novalis accelerator, while this difference was higher than 4 % for the treatment delivered on the CyberKnife, highlighting a small overdosing of the tumor volume. A good agreement was observed between gel and film dose profiles.
Conclusions: This study presents the successful implementation of 3D E2E QA tests for stereotactic radiotherapy with FXG gel dosimetry and a dual-wavelength reading method on an optical CT scanner. This dosimetric method provides 3D absolute dose distributions in the 0.25 - 10 Gy dose range with a high spatial resolution and a dose uncertainty of around 2 % (k=1).
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Associazione Italiana di Fisica Medica e Sanitaria. Published by Elsevier Ltd. All rights reserved.)
فهرسة مساهمة: Keywords: 3D dosimetry; Fricke-based gel dosimetry; Optical CT scanner; Stereotactic radiotherapy
المشرفين على المادة: S2VDY878QD (xylenol orange)
9000-70-8 (Gelatin)
تواريخ الأحداث: Date Created: 20230825 Date Completed: 20230918 Latest Revision: 20230918
رمز التحديث: 20231215
DOI: 10.1016/j.ejmp.2023.102656
PMID: 37625218
قاعدة البيانات: MEDLINE
الوصف
تدمد:1724-191X
DOI:10.1016/j.ejmp.2023.102656