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NIR-II Nanoprobes: A Review of Components-Based Approaches to Next-Generation Bioimaging Probes.

التفاصيل البيبلوغرافية
العنوان: NIR-II Nanoprobes: A Review of Components-Based Approaches to Next-Generation Bioimaging Probes.
المؤلفون: Dunn B; Department of Bioengineering, George Mason University, Fairfax, VA 22030, USA., Hanafi M; Department of Bioengineering, George Mason University, Fairfax, VA 22030, USA., Hummel J; Department of Physics, George Mason University, Fairfax, VA 22030, USA., Cressman JR; Department of Physics, George Mason University, Fairfax, VA 22030, USA., Veneziano R; Department of Bioengineering, George Mason University, Fairfax, VA 22030, USA., Chitnis PV; Department of Bioengineering, George Mason University, Fairfax, VA 22030, USA.
المصدر: Bioengineering (Basel, Switzerland) [Bioengineering (Basel)] 2023 Aug 11; Vol. 10 (8). Date of Electronic Publication: 2023 Aug 11.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101676056 Publication Model: Electronic Cited Medium: Print ISSN: 2306-5354 (Print) Linking ISSN: 23065354 NLM ISO Abbreviation: Bioengineering (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2014]-
مستخلص: Fluorescence and photoacoustic imaging techniques offer valuable insights into cell- and tissue-level processes. However, these optical imaging modalities are limited by scattering and absorption in tissue, resulting in the low-depth penetration of imaging. Contrast-enhanced imaging in the near-infrared window improves imaging penetration by taking advantage of reduced autofluorescence and scattering effects. Current contrast agents for fluorescence and photoacoustic imaging face several limitations from photostability and targeting specificity, highlighting the need for a novel imaging probe development. This review covers a broad range of near-infrared fluorescent and photoacoustic contrast agents, including organic dyes, polymers, and metallic nanostructures, focusing on their optical properties and applications in cellular and animal imaging. Similarly, we explore encapsulation and functionalization technologies toward building targeted, nanoscale imaging probes. Bioimaging applications such as angiography, tumor imaging, and the tracking of specific cell types are discussed. This review sheds light on recent advancements in fluorescent and photoacoustic nanoprobes in the near-infrared window. It serves as a valuable resource for researchers working in fields of biomedical imaging and nanotechnology, facilitating the development of innovative nanoprobes for improved diagnostic approaches in preclinical healthcare.
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فهرسة مساهمة: Keywords: NIR-II; emission; fluorescence; imaging; nanoprobe; photoacoustic
تواريخ الأحداث: Date Created: 20230826 Latest Revision: 20230919
رمز التحديث: 20230919
مُعرف محوري في PubMed: PMC10451329
DOI: 10.3390/bioengineering10080954
PMID: 37627839
قاعدة البيانات: MEDLINE
الوصف
تدمد:2306-5354
DOI:10.3390/bioengineering10080954