دورية أكاديمية
أعرض في EDS

Sustainable Electropolymerization of Zingerone and Its C2 Symmetric Dimer for Amperometric Biosensor Films.

التفاصيل البيبلوغرافية
العنوان: Sustainable Electropolymerization of Zingerone and Its C2 Symmetric Dimer for Amperometric Biosensor Films.
المؤلفون: Caval M; Dipartimento di Scienze Biomediche, Università Degli Studi di Sassari, 07100 Sassari, Italy., Dettori MA; Istituto di Chimica Biomolecolare, Consiglio Nazionale Ricerche, 07100 Sassari, Italy., Carta P; Istituto di Chimica Biomolecolare, Consiglio Nazionale Ricerche, 07100 Sassari, Italy., Dallocchio R; Istituto di Chimica Biomolecolare, Consiglio Nazionale Ricerche, 07100 Sassari, Italy., Dessì A; Istituto di Chimica Biomolecolare, Consiglio Nazionale Ricerche, 07100 Sassari, Italy., Marceddu S; Istituto di Istituto Scienze delle Produzioni Alimentari, Consiglio Nazionale Ricerche, 07100 Sassari, Italy., Serra PA; Dipartimento di Medicina, Chirurgia e Farmacia, Università Degli Studi di Sassari, 07100 Sassari, Italy., Fabbri D; Istituto di Chimica Biomolecolare, Consiglio Nazionale Ricerche, 07100 Sassari, Italy., Rocchitta G; Dipartimento di Medicina, Chirurgia e Farmacia, Università Degli Studi di Sassari, 07100 Sassari, Italy.
المصدر: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 11; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 11.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, c1995-
مواضيع طبية MeSH: Guaiacol* , Ascorbic Acid*, Glutamic Acid ; Polymers
مستخلص: Polymeric permselective films are frequently used for amperometric biosensors to prevent electroactive interference present in the target matrix. Phenylenediamines are the most commonly used for the deposition of shielding polymeric films against interfering species; however, even phenolic monomers have been utilized in the creation of these films for microsensors and biosensors. The purpose of this paper is to evaluate the performances of electrosynthesized polymers, layered by means of constant potential amperometry (CPA), of naturally occurring compound zingerone (ZING) and its dimer dehydrozingerone (ZING DIM), which was obtained by straight oxidative coupling reaction. The polymers showed interesting shielding characteristics against the main interfering species, such as ascorbic acid (AA): actually, polyZING exhibited an AA shielding aptitude comprised between 77.6 and 99.6%, comparable to that obtained with PPD. Moreover, a marked capability of increased monitoring of hydrogen peroxide (HP), when data were compared with bare metal results, was observed. In particular, polyZING showed increases ranging between 55.6 and 85.6%. In the present work, the molecular structures of the obtained polymers have been theorized and docking analyses were performed to understand their peculiar characteristics better. The structures were docked using the Lamarckian genetic algorithm (LGA). Glutamate biosensors based on those polymers were built, and their performances were compared with biosensors based on PPD, which is the most widespread polymer for the construction of amperometric biosensors.
References: Sensors (Basel). 2013 Jul 23;13(7):9522-35. (PMID: 23881145)
Beilstein J Org Chem. 2015 Aug 11;11:1398-411. (PMID: 26425195)
Analyst. 2015 May 21;140(10):3607-15. (PMID: 25857616)
J Chem Inf Model. 2019 Jul 22;59(7):3128-3135. (PMID: 31244091)
Anal Bioanal Chem. 2003 Oct;377(3):507-20. (PMID: 12920501)
Anal Bioanal Chem. 2016 Jul;408(17):4503-21. (PMID: 26935934)
Sensors (Basel). 2008 Feb 27;8(3):1366-1399. (PMID: 27879771)
Biomimetics (Basel). 2023 Jan 08;8(1):. (PMID: 36648812)
Mater Sci Eng C Mater Biol Appl. 2015 Oct;55:209-17. (PMID: 26117757)
Talanta. 2018 Aug 15;186:53-59. (PMID: 29784398)
J Mol Graph Model. 2012 Apr;34:18-27. (PMID: 22306414)
Ann Chim. 2003 Mar;93(3):209-21. (PMID: 12737484)
Antioxidants (Basel). 2021 Apr 19;10(4):. (PMID: 33921802)
Talanta. 2017 Jan 1;162:151-158. (PMID: 27837811)
Anal Chem. 2019 Jul 16;91(14):8732-8738. (PMID: 31276374)
J Comput Chem. 2004 Oct;25(13):1605-12. (PMID: 15264254)
Biosensors (Basel). 2019 Jul 30;9(3):. (PMID: 31366026)
Anal Chem. 2001 Nov 1;73(21):5310-5. (PMID: 11721934)
Biosensors (Basel). 2021 Sep 29;11(10):. (PMID: 34677316)
Anal Chim Acta. 2018 Aug 31;1022:113-123. (PMID: 29729731)
Analyst. 1997 Nov;122(11):1419-24. (PMID: 9474818)
Sci Rep. 2022 Jul 14;12(1):12033. (PMID: 35835916)
Molecules. 2021 Jul 27;26(15):. (PMID: 34361678)
Anal Chim Acta. 2022 Sep 1;1224:340205. (PMID: 35998987)
Amino Acids. 2013 Aug;45(2):327-38. (PMID: 23645386)
Chem Sci. 2019 Jul 22;10(35):8164-8170. (PMID: 31673321)
Anal Chim Acta. 2015 Jan 1;853:207-213. (PMID: 25467460)
Nat Rev Bioeng. 2023;1(5):346-360. (PMID: 37168735)
Talanta. 2023 Dec 1;265:124769. (PMID: 37329752)
J Anal Methods Chem. 2017;2017:1905968. (PMID: 28255500)
Biosensors (Basel). 2022 Feb 07;12(2):. (PMID: 35200363)
J Chem Theory Comput. 2021 Feb 9;17(2):1060-1073. (PMID: 33403848)
Anal Chem. 1999 Mar 1;71(5):1055-61. (PMID: 21662775)
J Am Chem Soc. 2007 Apr 4;129(13):3888-96. (PMID: 17355132)
Sensors (Basel). 2021 Dec 15;21(24):. (PMID: 34960482)
Soft Matter. 2021 Jul 7;17(26):6394-6403. (PMID: 34132302)
J Am Chem Soc. 2017 Aug 16;139(32):11207-11213. (PMID: 28712286)
معلومات مُعتمدة: Fondo per la ricerca di ateneo 2020 University of Sassari
فهرسة مساهمة: Keywords: biosensor; electropolymerization; molecular docking; zingerone; zingerone dimer
المشرفين على المادة: 4MMW850892 (zingerone)
6JKA7MAH9C (Guaiacol)
PQ6CK8PD0R (Ascorbic Acid)
3KX376GY7L (Glutamic Acid)
0 (Polymers)
تواريخ الأحداث: Date Created: 20230826 Date Completed: 20230828 Latest Revision: 20230829
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10459948
DOI: 10.3390/molecules28166017
PMID: 37630267
قاعدة البيانات: MEDLINE
الوصف
تدمد:1420-3049
DOI:10.3390/molecules28166017