دورية أكاديمية

The human placenta project: Funded studies, imaging technologies, and future directions.

التفاصيل البيبلوغرافية
العنوان: The human placenta project: Funded studies, imaging technologies, and future directions.
المؤلفون: Herrera CL; Department of Obstetrics and Gynecology, UT Southwestern Medical Center, and Parkland Health Dallas, Texas, USA; Green Center for Reproductive Biology Sciences, UT Southwestern Medical Center, Dallas, TX, USA. Electronic address: christina.herrera@utsouthwestern.edu., Kim MJ; University of Texas Southwestern Medical School, Dallas, TX, USA., Do QN; Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA., Owen DM; Department of Obstetrics and Gynecology, UT Southwestern Medical Center, and Parkland Health Dallas, Texas, USA; Green Center for Reproductive Biology Sciences, UT Southwestern Medical Center, Dallas, TX, USA., Fei B; Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA; Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, USA; Department of Bioengineering, University of Texas at Dallas, Dallas, TX, USA., Twickler DM; Department of Obstetrics and Gynecology, UT Southwestern Medical Center, and Parkland Health Dallas, Texas, USA; Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA., Spong CY; Department of Obstetrics and Gynecology, UT Southwestern Medical Center, and Parkland Health Dallas, Texas, USA.
المصدر: Placenta [Placenta] 2023 Oct; Vol. 142, pp. 27-35. Date of Electronic Publication: 2023 Aug 21.
نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8006349 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3102 (Electronic) Linking ISSN: 01434004 NLM ISO Abbreviation: Placenta Subsets: MEDLINE
أسماء مطبوعة: Publication: <2010- > : Amsterdam : Elsevier
Original Publication: London W.B. Saunders.
مواضيع طبية MeSH: Placenta Diseases* , Pregnancy Complications*, Child ; Humans ; Pregnancy ; Female ; Placenta/diagnostic imaging ; Fetal Development ; Fetus
مستخلص: The placenta plays a critical role in fetal development. It serves as a multi-functional organ that protects and nurtures the fetus during pregnancy. However, despite its importance, the intricacies of placental structure and function in normal and diseased states have remained largely unexplored. Thus, in 2014, the National Institute of Child Health and Human Development launched the Human Placenta Project (HPP). As of May 2023, the HPP has awarded over $101 million in research funds, resulting in 41 funded studies and 459 publications. We conducted a comprehensive review of these studies and publications to identify areas of funded research, advances in those areas, limitations of current research, and continued areas of need. This paper will specifically review the funded studies by the HPP, followed by an in-depth discussion on advances and gaps within placental-focused imaging. We highlight the progress within magnetic reasonance imaging and ultrasound, including development of tools for the assessment of placental function and structure.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
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معلومات مُعتمدة: K23 HD103876 United States HD NICHD NIH HHS; K25 HD104004 United States HD NICHD NIH HHS; L30 HD109864 United States HD NICHD NIH HHS
فهرسة مساهمة: Keywords: Human placenta project; Imaging; Magnetic resonance imaging; Placental function; Placental structure; Pregnancy; Ultrasound
تواريخ الأحداث: Date Created: 20230827 Date Completed: 20231023 Latest Revision: 20240826
رمز التحديث: 20240827
مُعرف محوري في PubMed: PMC11257151
DOI: 10.1016/j.placenta.2023.08.067
PMID: 37634371
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-3102
DOI:10.1016/j.placenta.2023.08.067