دورية أكاديمية
Effects of a low-iodine diet in post-thyroidectomy thyroid cancer patients undergoing I 131 therapy at the Vietnam National Cancer Hospital.
| العنوان: | Effects of a low-iodine diet in post-thyroidectomy thyroid cancer patients undergoing I 131 therapy at the Vietnam National Cancer Hospital. |
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| المؤلفون: | Hoang BV; Clinical Nutrition Centre, Vietnam National Cancer Hospital, Hanoi, Vietnam., Nguyen TTH; Clinical Nutrition Centre, Vietnam National Cancer Hospital, Hanoi, Vietnam., Duong YT; Clinical Nutrition Centre, Vietnam National Cancer Hospital, Hanoi, Vietnam., Nguyen HTT; Clinical Nutrition Centre, Vietnam National Cancer Hospital, Hanoi, Vietnam., Nguyen TH; School of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam., Nguyen TT; Clinical Nutrition Centre, Vietnam National Cancer Hospital, Hanoi, Vietnam., Nguyen LTT; School of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam., Le HT; Clinical Nutrition Centre, Vietnam National Cancer Hospital, Hanoi, Vietnam.; School of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam. |
| المصدر: | Nutrition and health [Nutr Health] 2023 Aug 27, pp. 2601060231197558. Date of Electronic Publication: 2023 Aug 27. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Country of Publication: England NLM ID: 8306569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0260-1060 (Print) Linking ISSN: 02601060 NLM ISO Abbreviation: Nutr Health Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2012- : London : Sage Original Publication: Berkhamsted, England : Academic Publishers, 1982- |
| مستخلص: | Background: I 131 therapy is regarded as an "internal surgery" (i.e., a non-invasive approach involving no incision or bleeding) that supports "external surgery" (i.e., using a scalpel) in completely eradicating the root cause of thyroid cancer. Limiting iodine intake is of paramount importance in I 131 therapy. I 131 therapy protocols recommend that patients follow a low-iodine diet, ideally with a maximum iodine intake of 50 μg/day for two weeks before the I 131 therapy. Methods: A pre-post compassion uncontrolled clinic intervention study was conducted on a group of over 70 post-thyroidectomy thyroid cancer patients with indications for I 131 therapy at the Vietnam National Cancer Hospital from December 2020 to December 2022. Aim : It aimed to assess the effects of a low-iodine diet on post-thyroidectomy thyroid cancer patients with indications for I 131 therapy. Results: The study found that following the intervention, the percentage of participants at risk of mild to moderate malnutrition, as assessed by the PG-SGA tool, decreased to 4.3% from 40.0% before the intervention, with a statistically significant difference of p < 0.001. There was a considerable improvement in the low calcemia level among the study participants, with 35.7% of patients experiencing hypocalcemia prior to the intervention, which reduced to 17.1% after the intervention. This difference was statistically significant ( p = 0.01). The study also revealed a urinary iodine level improvement among the study participants. Before the intervention, patients' average urinary iodine level was 14.9 ± 11.3 µg/dl. Following the intervention, it reduced to 12.7 ± 3.9 µg/dl, although this difference was not statistically significant ( p = 0.29). Patients' quality of life after adhering to the low-iodine diet tended to decline; however, the change in scores before and after the intervention did not show a significant difference. Conclusion: Despite its negative impact on patients' quality of life, active nutrition counseling and intervention during the low-iodine diet contributed to the substantial improvement in the hypocalcemia level and the reduced urinary iodine level among patients, which in turn could enhance the efficacy of the subsequent I 131 therapy. |
| فهرسة مساهمة: | Keywords: Nutritional intervention; low-iodine diet; quality of life; thyroid cancer patients |
| تواريخ الأحداث: | Date Created: 20230828 Latest Revision: 20230828 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1177/02601060231197558 |
| PMID: | 37635343 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0260-1060 |
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| DOI: | 10.1177/02601060231197558 |