دورية أكاديمية
Lymphatic Pathways on Indocyanine Green Lymphography in Patients with Labia Minora Hypertrophy.
| العنوان: | Lymphatic Pathways on Indocyanine Green Lymphography in Patients with Labia Minora Hypertrophy. |
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| المؤلفون: | Yuan Y; From the Gynecological Plastic Surgery Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College., Li F; From the Gynecological Plastic Surgery Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College., Zhou Y; From the Gynecological Plastic Surgery Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College., Li S; From the Gynecological Plastic Surgery Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College., Cao Y; From the Gynecological Plastic Surgery Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College., Liu M; From the Gynecological Plastic Surgery Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College., Li Y; From the Gynecological Plastic Surgery Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College., Li Q; From the Gynecological Plastic Surgery Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. |
| المصدر: | Plastic and reconstructive surgery [Plast Reconstr Surg] 2024 Sep 01; Vol. 154 (3), pp. 665-671. Date of Electronic Publication: 2023 Aug 29. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 1306050 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-4242 (Electronic) Linking ISSN: 00321052 NLM ISO Abbreviation: Plast Reconstr Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Original Publication: Baltimore : Williams & Wilkins, |
| مواضيع طبية MeSH: | Indocyanine Green*/administration & dosage , Lymphography*/methods , Hypertrophy*/diagnostic imaging , Vulva*/surgery , Vulva*/diagnostic imaging , Vulva*/pathology , Lymphatic Vessels*/diagnostic imaging , Lymphatic Vessels*/surgery, Humans ; Female ; Adult ; Middle Aged ; Lymphedema/diagnostic imaging ; Lymphedema/surgery ; Young Adult ; Retrospective Studies ; Coloring Agents/administration & dosage ; Adolescent |
| مستخلص: | Background: Labia minora hypertrophy (LH) is a growing aesthetic concern, yet its etiology and local lymphatic anatomy remain unclear. This study aimed to use indocyanine green (ICG) lymphography to investigate evidence of lymphedema in LH and clarify the anatomy of lymph vessels from the labia minora. Methods: Thirty-five patients with LH underwent preoperative ICG lymphography of their bilateral labia minora. The study reviewed demographic, ICG imaging, and measurement data to identify the characteristics of the superficial lymphatic anatomy in the labia minora. Results: The ICG lymphography findings revealed that 97.1% of the observed patterns were linear, and 2.9% were dermal backflow patterns. Further analysis of the linear patterns revealed the presence of 3 main superficial pathways originating from the labia minora and connecting to the labia majora and clitoral hood. These pathways were identified as the superior, median, and inferior channels. Based on the observed lymphatic mapping in the labia minora, 3 types were classified: type 1 (superior and inferior channels) accounted for 75.0% (51 sides), type 2 (median and inferior channels) accounted for 8.8% (6 sides), and type 3 (superior, median, and inferior channels) accounted for 16.2% (11 sides). Conclusions: The study demonstrates that ICG lymphography enables clear visualization of superficial lymph flow from the labia minora. It also suggests that lymphedema is not a common pathologic feature of LH. Understanding the lymphatic anatomy of the labia minora can provide valuable guidance for surgical interventions involving the female external genitalia. (Copyright © 2023 by the American Society of Plastic Surgeons.) |
| References: | Reddy J, Laufer MR. Hypertrophic labia minora. J Pediatr Adolesc Gynecol. 2010;23:3–6. Hayes JA, Temple-Smith MJ. What is the anatomical basis of labiaplasty? A review of normative datasets for female genital anatomy. Aust N Z J Obstet Gynaecol. 2021;61:331–338. Barrett MM, Carlson J. A clinicopathologic study of labia minora hypertrophy: signs of localized lymphedema were universal. J Low Genit Tract Dis. 2014;18:13–20. Gulia C, Zangari A, Briganti V, Bateni ZH, Porrello A, Piergentili R. Labia minora hypertrophy: causes, impact on women’s health, and treatment options. Int Urogynecol J. 2017;28:1453–1461. Ozer M, Mortimore I, Jansma EP, Mullender MG. Labiaplasty: motivation, techniques, and ethics. Nat Rev Urol. 2018;15:175–189. Yamamoto T, Yamamoto N, Yoshimatsu H, Hayami S, Narushima M, Koshima I. Indocyanine green lymphography for evaluation of genital lymphedema in secondary lower extremity lymphedema patients. J Vasc Surg Venous Lymphat Disord. 2013;1:400–405.e1. Qiang S, Li FY, Zhou Y, Cao YJ, Liu MC, Li Q. Long-term follow-up in labiaplasty in 414 women: a single-center experience in China. Ann Plast Surg. 2022;89:353–357. Granoff MD, Pardo JA, Johnson AR, et al. Superficial and functional lymphatic anatomy of the upper extremity. Plast Reconstr Surg. 2022;150:900–907. Sakai H, Kageyama T, Tsukuura R, Yamamoto T. Anatomical location of lymphatic pathways in the posterior thigh. Ann Plast Surg. 2022;88:330–334. Yamamoto T, Yamamoto N. Indocyanine green lymphography for evaluation of breast lymphedema secondary to breast cancer treatments. J Reconstr Microsurg. 2022;38:630–636. Yamamoto T, Yamamoto N, Doi K, et al. Indocyanine green-enhanced lymphography for upper extremity lymphedema: a novel severity staging system using dermal backflow patterns. Plast Reconstr Surg. 2011;128:941–947. Yamamoto T, Yamamoto N, Furuya M, Hayashi A, Koshima I. Genital lymphedema score: genital lymphedema severity scoring system based on subjective symptoms. Ann Plast Surg. 2016;77:119–121. Cao Y, Li F, Li S, Zhou Y, Li Q. A preliminary observational study on the vascular, nerve, and lymphatic anatomy and histology of the labia minora from cadaveric and surgical samples. Int Urogynecol J. 2021;32:1169–1176. Mihara M, Hayashi Y, Hara H, et al. High-accuracy diagnosis and regional classification of lymphedema using indocyanine green fluorescent lymphography after gynecologic cancer treatment. Ann Plast Surg. 2014;72:204–208. Hara H, Mihara M. Indocyanine green lymphographic and lymphoscintigraphic findings in genital lymphedema-genital pathway score. Lymphat Res Biol. 2017;15:356–359. Crane LM, Themelis G, Arts HJ, et al. Intraoperative near-infrared fluorescence imaging for sentinel lymph node detection in vulvar cancer: first clinical results. Gynecol Oncol. 2011;120:291–295. Levenback CF, Ali S, Coleman RL, et al. Lymphatic mapping and sentinel lymph node biopsy in women with squamous cell carcinoma of the vulva: a gynecologic oncology group study. J Clin Oncol. 2012;30:3786–3791. Moore DH. Reflections on vulvar tumors, lymphatic drainage, and sentinel lymph node biopsy. Gynecol Oncol. 2013;128:153–154. Suami H. Lymphosome concept: anatomical study of the lymphatic system. J Surg Oncol. 2017;115:13–17. Suami H, Scaglioni MF. Anatomy of the lymphatic system and the lymphosome concept with reference to lymphedema. Semin Plast Surg. 2018;32:5–11. Georgiou CA, Benatar M, Dumas P, et al. A cadaveric study of the arterial blood supply of the labia minora. Plast Reconstr Surg. 2015;136:167–178. Pavlista D, Eliska O. Superficial lymphatic drainage of the vulva and its relation to the regional nodes: an experimental study. Folia Morphol (Warsz) 2022;81:917–922. Zhou Y, Li Q, Li S, et al. Trilobal methods for composite reduction labiaplasty. Aesthetic Plast Surg. 2022;46:1472–1480. Michalski BM, Pfeifer JD, Mutch D, Council ML. Cancer of the vulva: a review. Dermatol Surg. 2021;47:174–183. Coleman RL, Ali S, Levenback CF, et al. Is bilateral lymphadenectomy for midline squamous carcinoma of the vulva always necessary? An analysis from Gynecologic Oncology Group (GOG) 173. Gynecol Oncol. 2013;128:155–159. Puppo V. Embryology and anatomy of the vulva: the female orgasm and women’s sexual health. Eur J Obstet Gynecol Reprod Biol. 2011;154:3–8. Long LY, Qiang PF, Ling T, et al. A new technique to map the lymphatic distribution and alignment of the penis. Anat Rec (Hoboken) 2015;298:1465–1471. Yamamoto T, Narushima M, Yoshimatsu H, et al. Minimally invasive lymphatic supermicrosurgery (MILS): indocyanine green lymphography-guided simultaneous multisite lymphaticovenular anastomoses via millimeter skin incisions. Ann Plast Surg. 2014;72:67–70. Hara H, Mihara M. Multilymphosome injection indocyanine green lymphography can detect more lymphatic vessels than lymphoscintigraphy in lymphedematous limbs. J Plast Reconstr Aesthet Surg. 2020;73:1025–1030. |
| المشرفين على المادة: | IX6J1063HV (Indocyanine Green) 0 (Coloring Agents) |
| تواريخ الأحداث: | Date Created: 20230830 Date Completed: 20240828 Latest Revision: 20240829 |
| رمز التحديث: | 20240830 |
| DOI: | 10.1097/PRS.0000000000011027 |
| PMID: | 37647514 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1529-4242 |
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| DOI: | 10.1097/PRS.0000000000011027 |