دورية أكاديمية

Effect of dual-optical pulses with temporal energy distribution on laser ablation performance in in vivo zebrafish model.

التفاصيل البيبلوغرافية
العنوان: Effect of dual-optical pulses with temporal energy distribution on laser ablation performance in in vivo zebrafish model.
المؤلفون: Shin H; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan, Republic of Korea., Lee Y; Marine-Integrated Biomedical Technology Center, Pukyong National University, Busan, Republic of Korea., Hwang J; Department of Biomedical Engineering, Division of Smart Healthcare, College of Information, Pukyong National University, Busan, Republic of Korea., Lim S; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan, Republic of Korea., Choi J; Research and Development, Bluecore Company, Busan, Republic of Korea., Gong SP; Division of Fisheries Life Science, Major in Aquaculture and Applied Life Science, Pukyong National University, Busan, Republic of Korea., Kang HW; Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan, Republic of Korea.; Marine-Integrated Biomedical Technology Center, Pukyong National University, Busan, Republic of Korea.; Department of Biomedical Engineering, Division of Smart Healthcare, College of Information, Pukyong National University, Busan, Republic of Korea.
المصدر: Journal of biophotonics [J Biophotonics] 2023 Dec; Vol. 16 (12), pp. e202300232. Date of Electronic Publication: 2023 Sep 18.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101318567 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1864-0648 (Electronic) Linking ISSN: 1864063X NLM ISO Abbreviation: J Biophotonics Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Weinheim : Wiley-VCH
مواضيع طبية MeSH: Laser Therapy* , Melanosis*/etiology , Melanosis*/surgery, Animals ; Zebrafish ; Hot Temperature
مستخلص: A Q-switched laser system has been used in a single-pulse mode for skin melasma treatments because of instant heat deposition in the target. Despite the efficient ablation of the melanophores in the skin, the single, high-fluence pulse often causes undesirable damage to the surrounding tissue, leading to high recurrence rates. This study aims to investigate the feasibility of dual-optical pulses with a temporal energy distribution on the melasma treatment in in vivo zebrafish models in comparison to that of the single optical pulse. Based on the optical detection, the dual-optical pulses had a temporal energy distribution ratio of 4:1 and an interval of 61 μs between the two consecutive pulses. According to the histological analysis, the dual pulses removed melanophores and induced a few apoptotic nuclei with minimal recurrence. This study demonstrated that the feasibility of dual-optical pulses (energy ratio = 4:1) could enhance the laser ablation performance in vivo.
(© 2023 Wiley-VCH GmbH.)
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معلومات مُعتمدة: S3157282 Ministry of SMEs and Startups; 2021R1A6A1A03039211 National Research Foundation of Korea
فهرسة مساهمة: Keywords: dual-optical pulsed laser; melanophores; melasma; zebrafish
تواريخ الأحداث: Date Created: 20230831 Date Completed: 20231228 Latest Revision: 20240403
رمز التحديث: 20240403
DOI: 10.1002/jbio.202300232
PMID: 37651611
قاعدة البيانات: MEDLINE
الوصف
تدمد:1864-0648
DOI:10.1002/jbio.202300232