دورية أكاديمية
أعرض في EDS

Correlation of the ultrasound thyroid imaging reporting and data system with cytology findings among patients in Uganda.

التفاصيل البيبلوغرافية
العنوان: Correlation of the ultrasound thyroid imaging reporting and data system with cytology findings among patients in Uganda.
المؤلفون: Isse HM; Department of Radiology and Radiotherapy, College of Health Science, MakerereUniversity, Kampala, Uganda. drhamdisom@gmail.com., Lukande R; Department of Pathology, College of Health Science, MakerereUniversity, Kampala, Uganda., Sereke SG; Department of Radiology and Radiotherapy, College of Health Science, MakerereUniversity, Kampala, Uganda., Odubu FJ; Department of Surgery, College of Health Science, Makerere University, Kampala, Uganda., Nassanga R; Department of Radiology and Radiotherapy, College of Health Science, MakerereUniversity, Kampala, Uganda., Bugeza S; Department of Radiology and Radiotherapy, College of Health Science, MakerereUniversity, Kampala, Uganda.
المصدر: Thyroid research [Thyroid Res] 2023 Sep 01; Vol. 16 (1), pp. 26. Date of Electronic Publication: 2023 Sep 01.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101469037 Publication Model: Electronic Cited Medium: Print ISSN: 1756-6614 (Print) Linking ISSN: 17566614 NLM ISO Abbreviation: Thyroid Res Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central Ltd., c2008-
مستخلص: Background: Ultrasonography is a noninvasive modality for the initial assessment of thyroid nodules. The American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) has demonstrated good performance in differentiating malignant thyroid nodules. However, the combination of ACR TI-RADS categories and cytology has not been studied extensively, in Uganda. The study aims to correlate ACR TI-RADS with cytology among patients referred for US-guided fine-needle aspiration at Mulago National Referral Hospital.
Methods: This was a hospital-based cross-sectional study that recruited 132 patients with thyroid nodules. Spearman's correlation was used to establish a relationship between TI-RADS and cytology findings. The diagnostic accuracy of TI-RADS was assessed using sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios.
Results: Of 132 study participants, 90% (n = 117) were females, and the mean age was 41 ± 13 years. One hundred sixty-one thyroid nodules were analyzed. More than half of the thyroid nodules (54.7%, n = 87) were solid or almost solid, 96.9% (n = 154) were shaped wider than tall, 57.2% (n = 91) had smooth margins, 83.7% (n = 133) were hyperechoic or isoechoic, and 88.7% (n = 141) had no echogenic foci. TI-RADS 3 was the most common at 42.9% (n = 69). The proportions of malignancy for TI-RADS 4 and TI-RADS 5 were 73.3% and 85.7%, respectively. The correlation between ACR TI-RADS and the Bethesda system of thyroid classification scores was r = 0.577. The sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios of ACR TI-RADS were 90.9%, 98.5%, 90%, 99.3%, 62.3, and 0.1, respectively.
Conclusion: We found that ACR TI-RADS classification is an appropriate and noninvasive method for assessing thyroid nodules in routine practice. It can safely reduce the number of unnecessary fine-needle aspiration in a significant proportion of benign thyroid lesions. Thyroid nodules classified as TI-RADS 3 should be followed routinely. ACR TI-RADS should be standardized as the screening tool in resource-limited areas.
(© 2023. The Author(s).)
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فهرسة مساهمة: Keywords: Cytology; Fine needle aspiration; TI-RADS; Thyroid cancer; Thyroid nodule; Ultrasound
تواريخ الأحداث: Date Created: 20230831 Latest Revision: 20231121
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10472606
DOI: 10.1186/s13044-023-00169-1
PMID: 37653537
قاعدة البيانات: MEDLINE
الوصف
تدمد:1756-6614
DOI:10.1186/s13044-023-00169-1