دورية أكاديمية
Active versus expectant management for premature rupture of membranes at term: A randomized, controlled study.
العنوان: | Active versus expectant management for premature rupture of membranes at term: A randomized, controlled study. |
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المؤلفون: | Awkadigwe FI; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Ezugwu FO; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Eleje GU; Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria.; Effective Care Research Unit, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi Campus, Nigeria., Nweze SO; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Odugu BU; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Dinwoke VO; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Olu EA; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Ortuanya KE; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Ezenwaeze MN; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Eze OC; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Onyekpa JI; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Ofor IJ; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Onah OO; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Omeje CU; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Ezike AU; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Enyinna PK; Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology (ESUT) Teaching Hospital, Parklane, Enugu, Nigeria., Malachy DE; Effective Care Research Unit, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi Campus, Nigeria., Okafor CG; Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, Anambra State, Nigeria. |
المصدر: | The Journal of international medical research [J Int Med Res] 2023 Aug; Vol. 51 (8), pp. 3000605231195451. |
نوع المنشور: | Randomized Controlled Trial; Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Sage Publications Country of Publication: England NLM ID: 0346411 Publication Model: Print Cited Medium: Internet ISSN: 1473-2300 (Electronic) Linking ISSN: 03000605 NLM ISO Abbreviation: J Int Med Res Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Nov. 2012- : London : Sage Publications Original Publication: Northampton, Eng., Cambridge Medical Publications ltd. |
مواضيع طبية MeSH: | Cesarean Section* , Watchful Waiting* , Fetal Membranes, Premature Rupture*/diagnosis , Fetal Membranes, Premature Rupture*/therapy, Female ; Humans ; Pregnancy ; Prospective Studies ; Research Design |
مستخلص: | Objective: To compare the effects on feto-maternal outcomes of expectant versus active management for premature rupture of membranes (PROM) at term. Methods: This was a prospective randomized (1:1) controlled study involving 86 pregnant-women who received either expectant management (n = 43) or active management with misoprostol (n = 43) for PROM at term. Primary outcome was route of delivery. Secondary outcomes were: PROM to presentation interval; latency period; PROM to delivery interval; recruitment to delivery interval; labour and delivery complications. Results: Baseline-characteristics were similar between groups. There was no significant difference between active and expectant groups in mean PROM to presentation/admission, or PROM to delivery. However, mean latency period (11.1 ± 7.3 hours vs 8.8 ± 5.5 hours) and mean recruitment to delivery intervals after PROM (14.7 ± 5.2 hours vs 11.8 ± 5.0 hours) were significantly shorter for the active group compared with the expectant group. Although the rate of caesarean section was less in expectant management group (21%) compared with the active management group (30%), the difference was not statistically significant. There were no significant differences between groups in delivery or perinatal complications. Conclusion: Active and expectant management for PROM at term gave comparable outcomes in terms of methods of delivery and complications. However, active management significantly shortened the latency period and induction to delivery intervals compared with expectant management. Trial-Registration: Pan-African-trial-registry-(PACTR)-approval-number PACTR202206797734088. |
References: | Acta Obstet Gynecol Scand. 2002 Apr;81(4):293-300. (PMID: 11952457) Obstet Gynecol. 1984 May;63(5):697-702. (PMID: 6717874) S Afr Med J. 1989 Jan 21;75(2):54-6. (PMID: 2913680) Am J Obstet Gynecol. 1998 Sep;179(3 Pt 1):635-9. (PMID: 9757963) Am J Obstet Gynecol. 2003 Sep;189(3):720-4. (PMID: 14526301) Am J Obstet Gynecol. 1969 Jun 15;104(4):544-50. (PMID: 4182350) Cochrane Database Syst Rev. 2017 Mar 03;3:CD004735. (PMID: 28257562) J Matern Fetal Neonatal Med. 2010 Aug;23(8):828-41. (PMID: 20158393) BJOG. 2005 Sep;112(9):1284-90. (PMID: 16101609) South Med J. 1986 Aug;79(8):955-8. (PMID: 3526572) Obstet Gynecol. 1978 Jul;52(1):17-21. (PMID: 683624) Br J Obstet Gynaecol. 1992 Jul;99(7):557-62. (PMID: 1525095) J Obstet Gynaecol Res. 2015 Jan;41(1):29-38. (PMID: 25164109) Int J Gynaecol Obstet. 1994 Oct;47(1):7-15. (PMID: 7813758) J Matern Fetal Neonatal Med. 2016;29(8):1291-6. (PMID: 26030681) BMJ. 2010 Mar 23;340:c332. (PMID: 20332509) J Perinat Med. 2017 Jan 1;45(1):105-112. (PMID: 27855117) Science. 2014 Aug 15;345(6198):760-5. (PMID: 25124429) BJOG. 2002 Dec;109(12):1354-8. (PMID: 12504970) J Matern Fetal Neonatal Med. 2008 Oct;21(10):732-44. (PMID: 19012190) Am J Obstet Gynecol. 1993 Feb;168(2):585-91. (PMID: 8438933) Obstet Gynecol. 2007 Apr;109(4):1007-19. (PMID: 17400872) Arch Gynecol Obstet. 2012 Jan;285(1):21-5. (PMID: 21475966) Am J Obstet Gynecol. 2010 Oct;203(4):361.e1-361.e30. (PMID: 20673868) Placenta. 2009 Mar;30(3):207-15. (PMID: 19152976) Am J Obstet Gynecol. 1992 Mar;166(3):836-43. (PMID: 1550149) Int J Health Sci (Qassim). 2021 Nov-Dec;15(6):16-22. (PMID: 34912184) Rev Obstet Gynecol. 2008 Winter;1(1):11-22. (PMID: 18701929) Obstet Gynecol. 1989 Jul;74(1):93-7. (PMID: 2733949) Int J Gynaecol Obstet. 2019 Feb;144(2):180-186. (PMID: 30387138) Curr Opin Obstet Gynecol. 2003 Apr;15(2):91-9. (PMID: 12634599) Acta Obstet Gynecol Scand. 2004 Jul;83(7):622-6. (PMID: 15225185) Cochrane Database Syst Rev. 2017 Jan 04;1:CD005302. (PMID: 28050900) Clin Obstet Gynecol. 1988 Sep;31(3):553-84. (PMID: 3066544) |
فهرسة مساهمة: | Keywords: PROM; Premature rupture of membranes; Prostaglandin–E1 analogue; active management; expectant management |
تواريخ الأحداث: | Date Created: 20230901 Date Completed: 20230907 Latest Revision: 20230907 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC10478565 |
DOI: | 10.1177/03000605231195451 |
PMID: | 37656970 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1473-2300 |
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DOI: | 10.1177/03000605231195451 |