دورية أكاديمية

Rutin intake mitigates the injury of blue light irradiation by altering aging rates of mortality in Drosophila model.

التفاصيل البيبلوغرافية
العنوان: Rutin intake mitigates the injury of blue light irradiation by altering aging rates of mortality in Drosophila model.
المؤلفون: Tang H; College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China., Li X; College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China., Liu X; College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China., Xu Y; College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China., Shen J; College of Artificial Intelligence, Hangzhou Dianzi University, Hangzhou, China.
المصدر: Photochemistry and photobiology [Photochem Photobiol] 2024 May-Jun; Vol. 100 (3), pp. 524-529. Date of Electronic Publication: 2023 Sep 04.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Society for Photobiology Country of Publication: United States NLM ID: 0376425 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1751-1097 (Electronic) Linking ISSN: 00318655 NLM ISO Abbreviation: Photochem Photobiol Subsets: MEDLINE
أسماء مطبوعة: Publication: <2004->: Lawrence KS : American Society for Photobiology
Original Publication: Augusta, GA: American Society for Photobiology, <1996->
مواضيع طبية MeSH: Blue Light*/adverse effects , Rutin*/pharmacology, Animals ; Female ; Male ; Aging/drug effects ; Aging/radiation effects ; Antioxidants/pharmacology ; Drosophila ; Drosophila melanogaster/drug effects ; Sleep/drug effects ; Sleep/radiation effects
مستخلص: Blue light is known as one of the harmful light pollution that has complex effects on organisms. The massive use of LED lights in cities has greatly increased the frequency of human exposure to blue light, and therefore the hazards of blue light are receiving widespread attention. In our study, Drosophila was used as the model organism to explore the ability of the flavonoid rutin to resist blue light damage under the intensity of 3000 Lux. Siler model analysis was performed. Our results showed sex-specific pattern of rutin as an effective antioxidant. Rutin could help female flies to reduce the initial adult mortality and male flies to slow the increase of adult mortality under blue light irradiation, thus prolonging their average lifespan. Furthermore, after the intake of rutin, the locomotor activity of Drosophila under blue light irradiation was significantly increased, and the total sleep time was significantly decreased. In summary, our results provide preliminary support for exploring the mechanism of rutin against blue light damage.
(© 2023 American Society for Photobiology.)
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معلومات مُعتمدة: LY22C060002 Natural Science Foundation of Zhejiang Province
فهرسة مساهمة: Keywords: Siler model; blue light; lifespan; locomotor activity; rutin
المشرفين على المادة: 0 (Antioxidants)
5G06TVY3R7 (Rutin)
تواريخ الأحداث: Date Created: 20230904 Date Completed: 20240524 Latest Revision: 20240613
رمز التحديث: 20240614
DOI: 10.1111/php.13848
PMID: 37665025
قاعدة البيانات: MEDLINE
الوصف
تدمد:1751-1097
DOI:10.1111/php.13848