دورية أكاديمية
Using a chat-based informed consent tool in large-scale genomic research.
| العنوان: | Using a chat-based informed consent tool in large-scale genomic research. |
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| المؤلفون: | Savage SK; Invitae Corporation, San Francisco, CA, United States., LoTempio J; Institute for Clinical and Translational Science, University of California, Irvine, CA, United States., Smith ED; Invitae Corporation, San Francisco, CA, United States., Andrew EH; Division of Genetics and Metabolism, Children's National Rare Disease Institute, Washington, DC, United States.; Center for Genetic Medicine Research, Children's National Research Institute, Washington, DC, United States., Mas G; Invitae Corporation, San Francisco, CA, United States., Kahn-Kirby AH; Invitae Corporation, San Francisco, CA, United States.; Institute for Clinical and Translational Science, University of California, Irvine, CA, United States., Délot E; Center for Genetic Medicine Research, Children's National Research Institute, Washington, DC, United States.; Department of Genomics and Precision Medicine, George Washington University, Washington, DC, United States., Cohen AJ; Center for Genetic Medicine Research, Children's National Research Institute, Washington, DC, United States., Pitsava G; Center for Genetic Medicine Research, Children's National Research Institute, Washington, DC, United States., Nussbaum R; Invitae Corporation, San Francisco, CA, United States., Fusaro VA; Invitae Corporation, San Francisco, CA, United States.; Institute for Clinical and Translational Science, University of California, Irvine, CA, United States., Berger S; Division of Genetics and Metabolism, Children's National Rare Disease Institute, Washington, DC, United States.; Center for Genetic Medicine Research, Children's National Research Institute, Washington, DC, United States.; Department of Genomics and Precision Medicine, George Washington University, Washington, DC, United States., Vilain E; Institute for Clinical and Translational Science, University of California, Irvine, CA, United States.; Center for Genetic Medicine Research, Children's National Research Institute, Washington, DC, United States.; Department of Genomics and Precision Medicine, George Washington University, Washington, DC, United States. |
| المصدر: | Journal of the American Medical Informatics Association : JAMIA [J Am Med Inform Assoc] 2024 Jan 18; Vol. 31 (2), pp. 472-478. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9430800 Publication Model: Print Cited Medium: Internet ISSN: 1527-974X (Electronic) Linking ISSN: 10675027 NLM ISO Abbreviation: J Am Med Inform Assoc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2015- : Oxford : Oxford University Press Original Publication: Philadelphia, PA : Hanley & Belfus, c1993- |
| مواضيع طبية MeSH: | Informed Consent* , Genomics*, Humans ; Prospective Studies ; Software ; Communication |
| مستخلص: | Objective: We implemented a chatbot consent tool to shift the time burden from study staff in support of a national genomics research study. Materials and Methods: We created an Institutional Review Board-approved script for automated chat-based consent. We compared data from prospective participants who used the tool or had traditional consent conversations with study staff. Results: Chat-based consent, completed on a user's schedule, was shorter than the traditional conversation. This did not lead to a significant change in affirmative consents. Within affirmative consents and declines, more prospective participants completed the chat-based process. A quiz to assess chat-based consent user understanding had a high pass rate with no reported negative experiences. Conclusion: Our report shows that a structured script can convey important information while realizing the benefits of automation and burden shifting. Analysis suggests that it may be advantageous to use chatbots to scale this rate-limiting step in large research projects. (© The Author(s) 2023. Published by Oxford University Press on behalf of the American Medical Informatics Association.) |
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| معلومات مُعتمدة: | U01 HG011745 United States HG NHGRI NIH HHS; UL1 TR001414 United States TR NCATS NIH HHS; 5UL1TR001414 United States TR NCATS NIH HHS; 1U01HG011745 United States HG NHGRI NIH HHS |
| فهرسة مساهمة: | Keywords: chatbot; genetic counseling; genomics; informed consent; large-scale research |
| تواريخ الأحداث: | Date Created: 20230904 Date Completed: 20240122 Latest Revision: 20240210 |
| رمز التحديث: | 20240210 |
| مُعرف محوري في PubMed: | PMC10797258 |
| DOI: | 10.1093/jamia/ocad181 |
| PMID: | 37665746 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1527-974X |
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| DOI: | 10.1093/jamia/ocad181 |