دورية أكاديمية
أعرض في EDS

Preoperative ALBI grade predicts mortality in patients undergoing curative surgery for pancreatic head cancer.

التفاصيل البيبلوغرافية
العنوان: Preoperative ALBI grade predicts mortality in patients undergoing curative surgery for pancreatic head cancer.
المؤلفون: Azili C; Department of General Surgery, Division of Surgical Oncology, Ankara University Faculty of Medicine, Ankara, Turkey., Tamam S, Benk MS, Deryol R, Culcu S, Unal AE
المصدر: Medicine [Medicine (Baltimore)] 2023 Sep 08; Vol. 102 (36), pp. e35069.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 2985248R Publication Model: Print Cited Medium: Internet ISSN: 1536-5964 (Electronic) Linking ISSN: 00257974 NLM ISO Abbreviation: Medicine (Baltimore) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, Md : Lippincott Williams & Wilkins
مواضيع طبية MeSH: Bilirubin* , Pancreatic Neoplasms*/surgery, Humans ; Female ; Male ; Retrospective Studies ; Albumins ; Pancreatic Neoplasms
مستخلص: The clinical significance of the albumin-bilirubin (ALBI) grade in patients with pancreatic head cancer (PHC) undergoing surgery is unknown. Preoperative ALBI grade is believed to be influenced by tumor burden. This study aimed to develop and validate the ALBI grade as a preoperative prognostic model for predicting the survival of patients with PHC. This is a retrospective study of Whipple procedures performed on PHC patients between January 2013 and December 2022. ALBI grade was compared to age, gender, type of operation, presence of complications, type of complications, Clavien-Dindo classification, total bilirubin levels, and albumin levels. Of the series, 46 (41.1%) of the 112 patients were female, while 66 (58.9%) were male. The rate of complications following Whipple procedures was 36.6% (n = 41). The overall mortality hazard ratio increased significantly with increasing ALBI grades (HR: 1538, hazard ratio mean: -1602). Hospital mortality increased 2.84 times as the ALBI grade increased. The model's accuracy of 88.4% showed that the ALBI grade directly affected both the overall mortality rate and the hospital rate. But there was no statistically significant difference between the ALBI grade and other variables. Multivariate regression analysis identified the preoperative ALBI grade as an independent predictor of mortality (P = .006). To the best of our knowledge, this is the first study to identify preoperative ALBI grade as an independent predictor of survival in PHC. It was found that the ALBI grade of -1602 was a new grading system that would be more predictive of mortality in PHC.
Competing Interests: The authors have no funding and conflicts of interest to disclose.
(Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.)
References: Sci Rep. 2020 Apr 29;10(1):7290. (PMID: 32350365)
Expert Rev Gastroenterol Hepatol. 2022 Sep;16(9):903-911. (PMID: 35999514)
Surgery. 2017 Mar;161(3):584-591. (PMID: 28040257)
Heart Lung Circ. 2020 Sep;29(9):1328-1337. (PMID: 32165085)
Ann Transl Med. 2019 Aug;7(16):367. (PMID: 31555681)
N Engl J Med. 2015 Oct 22;373(17):1627-39. (PMID: 26412456)
JHEP Rep. 2021 Aug 05;3(5):100347. (PMID: 34505035)
Cancer. 2022 Dec 15;128(24):4251-4284. (PMID: 36301149)
Acta Clin Croat. 2018 Jun;57(2):292-300. (PMID: 30431722)
BMC Gastroenterol. 2021 Oct 19;21(1):386. (PMID: 34666694)
Surgeon. 2020 Jun;18(3):178-186. (PMID: 31601470)
Scand J Gastroenterol. 2023 Jan;58(1):61-69. (PMID: 35830511)
PLoS One. 2018 Dec 12;13(12):e0208903. (PMID: 30540824)
World J Gastroenterol. 2018 May 21;24(19):2047-2060. (PMID: 29785074)
Pediatr Rheumatol Online J. 2021 Sep 25;19(1):147. (PMID: 34563210)
Expert Rev Gastroenterol Hepatol. 2016 Aug;10(8):971-80. (PMID: 27070325)
J Hepatol. 2017 Mar;66(3):661-663. (PMID: 27890792)
Clin Colorectal Cancer. 2019 Mar;18(1):e61-e68. (PMID: 30348618)
Glob Heart. 2022 Oct 11;17(1):73. (PMID: 36382161)
Dig Liver Dis. 2019 May;51(5):681-688. (PMID: 30327251)
Medicine (Baltimore). 2021 Mar 19;100(11):e24476. (PMID: 33725934)
J Clin Oncol. 2015 Feb 20;33(6):550-8. (PMID: 25512453)
Liver Cancer. 2017 Nov;6(4):377-379. (PMID: 29234641)
Ann Surg Oncol. 2019 Dec;26(Suppl 3):598-599. (PMID: 31037436)
Invest New Drugs. 2015 Dec;33(6):1257-62. (PMID: 26462681)
Acta Radiol. 2019 Jun;60(6):702-709. (PMID: 30205701)
Int Heart J. 2021 Jul 30;62(4):829-836. (PMID: 34276023)
Evid Based Complement Alternat Med. 2022 Jul 7;2022:1801230. (PMID: 35845571)
Nat Rev Dis Primers. 2018 Jan 18;4:17105. (PMID: 29345251)
J Gastroenterol Hepatol. 2016 Jul;31(7):1300-6. (PMID: 26751608)
J Cancer. 2019 Aug 27;10(20):4836-4845. (PMID: 31598154)
Gland Surg. 2022 Mar;11(3):576-587. (PMID: 35402206)
Cancer Treat Rev. 2014 Jul;40(6):685-91. (PMID: 24321611)
Medicine (Baltimore). 2021 Jun 18;100(24):e26265. (PMID: 34128857)
Dig Dis Sci. 2019 Jun;64(6):1695-1704. (PMID: 30637547)
Sci Rep. 2021 Jul 23;11(1):15057. (PMID: 34301991)
Ann Surg. 2009 Aug;250(2):187-96. (PMID: 19638912)
Sci Immunol. 2022 Sep 9;7(75):eabn0704. (PMID: 36083892)
Anticancer Res. 2021 Mar;41(3):1621-1628. (PMID: 33788758)
In Vivo. 2021 Mar-Apr;35(2):1163-1168. (PMID: 33622916)
JHEP Rep. 2022 Aug 18;4(10):100557. (PMID: 36124124)
Cancers (Basel). 2021 Jul 28;13(15):. (PMID: 34359695)
Cancers (Basel). 2021 Aug 27;13(17):. (PMID: 34503135)
BMC Gastroenterol. 2022 Jun 14;22(1):295. (PMID: 35701739)
Ann Surg Oncol. 2019 Mar;26(3):791-799. (PMID: 30617869)
المشرفين على المادة: RFM9X3LJ49 (Bilirubin)
0 (Albumins)
تواريخ الأحداث: Date Created: 20230908 Date Completed: 20230911 Latest Revision: 20231213
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10489451
DOI: 10.1097/MD.0000000000035069
PMID: 37682123
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-5964
DOI:10.1097/MD.0000000000035069