دورية أكاديمية
The Rising Incidence of Hyperinsulinemic Hypoglycemia: Connection With Maternal Health.
| العنوان: | The Rising Incidence of Hyperinsulinemic Hypoglycemia: Connection With Maternal Health. |
|---|---|
| المؤلفون: | Sasidharan Pillai S; Division of Pediatric Endocrinology, Hasbro Children's Hospital, Providence, Rhode Island, USA; The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA., Fredette ME; Division of Pediatric Endocrinology, Hasbro Children's Hospital, Providence, Rhode Island, USA; The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA., Tanzer JR; Center for Statistical Sciences, Brown University, Providence, Rhode Island, USA., Hoffman L; Women and Infants Hospital, Providence, Rhode Island, USA., Topor LS; Division of Pediatric Endocrinology, Hasbro Children's Hospital, Providence, Rhode Island, USA; The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA. Electronic address: lisa_swartz_topor@brown.edu. |
| المصدر: | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists [Endocr Pract] 2023 Dec; Vol. 29 (12), pp. 980-985. Date of Electronic Publication: 2023 Sep 07. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9607439 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1530-891X (Print) Linking ISSN: 1530891X NLM ISO Abbreviation: Endocr Pract Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2021- : [New York] : Elsevier Inc. Original Publication: Jacksonville, Fla. : The College and the Association, |
| مواضيع طبية MeSH: | Hypoglycemia*/epidemiology , Hypertension, Pregnancy-Induced* , Hyperinsulinism*/complications , Hyperinsulinism*/epidemiology , COVID-19*/epidemiology , COVID-19*/complications, Infant ; Female ; Pregnancy ; Humans ; Child ; Incidence ; Maternal Health ; Pandemics |
| مستخلص: | Objective: Due to a perceived rise in hyperinsulinemic hypoglycemia (HH) cases over time, notably during the COVID-19 pandemic, institutional experiences between 2013 and 2021 were reviewed to evaluate trends, characteristics, and outcomes in children with HH. Methods: Charts of all children diagnosed with HH during the study period and evaluated by Pediatric Endocrinology were reviewed. HH was defined per Pediatric Endocrine Society guidelines. Regression analysis compared rates of change in HH cases and maternal risk factors over time. Results: The incidence of HH began to rise in April 2016 and became significant in March 2017 (P < .001), with a more rapid rate of rise during the first year of the COVID-19 pandemic (P < .001). Seventy-four children with HH were identified over 9 years; 43% (n = 32) were diagnosed in 2020-2021. Maternal hypertensive disorders demonstrated longitudinal association with hyperinsulinism cases (P < .001). Conclusion: While HH diagnoses were on the rise for much of the 9-year study period, nearly half of all infants were diagnosed during the COVID-19 pandemic in 2020 to 21. The trends in HH diagnoses correlated with maternal hypertensive disorders. More studies exploring the roles of maternal health, hypertension, and stress and development of HH in offspring are needed. Competing Interests: Disclosure The authors have no multiplicity of interest to disclose. (Copyright © 2023 AACE. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: COVID-19; congenital hyperinsulinism; hypoglycemia; maternal hypertension; neonatology; perinatal stress |
| تواريخ الأحداث: | Date Created: 20230908 Date Completed: 20231216 Latest Revision: 20231216 |
| رمز التحديث: | 20231217 |
| DOI: | 10.1016/j.eprac.2023.09.001 |
| PMID: | 37683825 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1530-891X |
|---|---|
| DOI: | 10.1016/j.eprac.2023.09.001 |