دورية أكاديمية
أعرض في EDS

The Impact of Biomaterial Surface Properties on Engineering Neural Tissue for Spinal Cord Regeneration.

التفاصيل البيبلوغرافية
العنوان: The Impact of Biomaterial Surface Properties on Engineering Neural Tissue for Spinal Cord Regeneration.
المؤلفون: da Silva VA; Laboratório de Neurogenética, Universidade Federal do ABC, Alameda da Universidade s/n, São Bernardo do Campo 09606-070, SP, Brazil., Bobotis BC; Laboratório de Neurogenética, Universidade Federal do ABC, Alameda da Universidade s/n, São Bernardo do Campo 09606-070, SP, Brazil., Correia FF; Laboratório de Neurogenética, Universidade Federal do ABC, Alameda da Universidade s/n, São Bernardo do Campo 09606-070, SP, Brazil., Lima-Vasconcellos TH; Laboratório de Neurogenética, Universidade Federal do ABC, Alameda da Universidade s/n, São Bernardo do Campo 09606-070, SP, Brazil., Chiarantin GMD; Laboratório de Neurogenética, Universidade Federal do ABC, Alameda da Universidade s/n, São Bernardo do Campo 09606-070, SP, Brazil., De La Vega L; Department of Mechanical Engineering, University of Victoria, Victoria, BC V8W 2Y2, Canada., Lombello CB; Centro de Engenharia, Modelagem e Ciências Sociais Aplicadas, Universidade Federal do ABC, São Bernardo do Campo 09606-070, SP, Brazil., Willerth SM; Department of Mechanical Engineering, University of Victoria, Victoria, BC V8W 2Y2, Canada.; Division of Medical Sciences, University of Victoria, Victoria, BC V8W 2Y2, Canada., Malmonge SM; Centro de Engenharia, Modelagem e Ciências Sociais Aplicadas, Universidade Federal do ABC, São Bernardo do Campo 09606-070, SP, Brazil., Paschon V; Laboratório de Neurogenética, Universidade Federal do ABC, Alameda da Universidade s/n, São Bernardo do Campo 09606-070, SP, Brazil., Kihara AH; Laboratório de Neurogenética, Universidade Federal do ABC, Alameda da Universidade s/n, São Bernardo do Campo 09606-070, SP, Brazil.
المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 04; Vol. 24 (17). Date of Electronic Publication: 2023 Sep 04.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, [2000-
مواضيع طبية MeSH: Spinal Cord Regeneration* , Induced Pluripotent Stem Cells* , Nerve Tissue* , Spinal Cord Injuries*/therapy, Animals ; Rats ; Humans ; Biocompatible Materials/pharmacology ; Tissue Engineering
مستخلص: Tissue engineering for spinal cord injury (SCI) remains a complex and challenging task. Biomaterial scaffolds have been suggested as a potential solution for supporting cell survival and differentiation at the injury site. However, different biomaterials display multiple properties that significantly impact neural tissue at a cellular level. Here, we evaluated the behavior of different cell lines seeded on chitosan (CHI), poly (ε-caprolactone) (PCL), and poly (L-lactic acid) (PLLA) scaffolds. We demonstrated that the surface properties of a material play a crucial role in cell morphology and differentiation. While the direct contact of a polymer with the cells did not cause cytotoxicity or inhibit the spread of neural progenitor cells derived from neurospheres (NPCdn), neonatal rat spinal cord cells (SCC) and NPCdn only attached and matured on PCL and PLLA surfaces. Scanning electron microscopy and computational analysis suggested that cells attached to the material's surface emerged into distinct morphological populations. Flow cytometry revealed a higher differentiation of neural progenitor cells derived from human induced pluripotent stem cells (hiPSC-NPC) into glial cells on all biomaterials. Immunofluorescence assays demonstrated that PCL and PLLA guided neuronal differentiation and network development in SCC. Our data emphasize the importance of selecting appropriate biomaterials for tissue engineering in SCI treatment.
References: Int J Nanomedicine. 2012;7:5577-91. (PMID: 23144561)
Adv Drug Deliv Rev. 2016 Dec 15;107:206-212. (PMID: 27125190)
Dev Neurobiol. 2010 Jul;70(8):589-603. (PMID: 20213755)
Bioact Mater. 2021 Jul 15;9:358-372. (PMID: 34820576)
Biomaterials. 2012 Aug;33(23):5672-82. (PMID: 22591608)
Neuron. 2000 Oct;28(1):69-80. (PMID: 11086984)
Neurotoxicology. 2020 Jan;76:33-43. (PMID: 31605718)
Biomater Sci. 2023 May 16;11(10):3414-3430. (PMID: 37000528)
Colloids Surf B Biointerfaces. 2018 Jul 1;167:93-103. (PMID: 29627682)
J Biomed Mater Res A. 2008 Nov;87(2):392-404. (PMID: 18186068)
J Pers Med. 2022 Jul 11;12(7):. (PMID: 35887623)
Neural Regen Res. 2015 May;10(5):726-42. (PMID: 26109946)
Int J Pharm. 2015 Jul 25;490(1-2):112-30. (PMID: 25997660)
Methods Mol Biol. 2011;750:61-77. (PMID: 21618083)
Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3524-3539. (PMID: 31437011)
J Spinal Cord Med. 2009;32(2):105-14. (PMID: 19569457)
PLoS One. 2012;7(7):e40154. (PMID: 22802953)
Biomaterials. 2018 Feb;154:223-233. (PMID: 29132047)
Int J Mol Sci. 2019 May 31;20(11):. (PMID: 31159345)
Int J Mol Sci. 2018 Mar 30;19(4):. (PMID: 29601528)
Int J Mol Sci. 2015 Aug 05;16(8):18149-84. (PMID: 26251901)
Neuron. 2007 May 3;54(3):357-69. (PMID: 17481390)
Polymers (Basel). 2022 Jun 07;14(12):. (PMID: 35745883)
Adv Drug Deliv Rev. 2013 Aug;65(9):1234-70. (PMID: 23872012)
PLoS One. 2013 Apr 09;8(4):e60486. (PMID: 23585836)
Curr Protoc Microbiol. 2008 Nov;Appendix 4:Appendix 4E. (PMID: 19016439)
J Biomed Sci. 2018 Dec 20;25(1):90. (PMID: 30572957)
Front Cell Neurosci. 2018 Jan 11;11:430. (PMID: 29375316)
Polymers (Basel). 2021 Aug 17;13(16):. (PMID: 34451293)
Int J Mol Sci. 2023 Feb 14;24(4):. (PMID: 36835233)
Neurol Res Int. 2011;2011:564089. (PMID: 21766025)
Biomaterials. 2008 Apr;29(12):1776-84. (PMID: 18222536)
Acta Biomater. 2010 Jul;6(7):2711-20. (PMID: 20080216)
Nat Rev Dis Primers. 2017 Apr 27;3:17018. (PMID: 28447605)
Int J Mol Sci. 2023 Jun 23;24(13):. (PMID: 37445718)
J Cell Physiol. 2005 Jul;204(1):198-209. (PMID: 15669099)
Toxicol Rep. 2017 Jul 24;4:427-430. (PMID: 28959669)
Sci Rep. 2019 Oct 1;9(1):14063. (PMID: 31575916)
Cell Transplant. 2011;20(1):37-47. (PMID: 21054953)
Regen Med. 2012 Mar;7(2):207-24. (PMID: 22397610)
Biomark Insights. 2015 May 26;10 Suppl 1:61-70. (PMID: 36876191)
Mar Drugs. 2014 Dec 29;13(1):141-58. (PMID: 25551781)
Adv Mater. 2014 Mar 26;26(12):1846-85. (PMID: 24677434)
Biotechnol Adv. 2012 Jan-Feb;30(1):321-8. (PMID: 21756992)
J Clin Invest. 2012 Nov;122(11):3824-34. (PMID: 23114605)
Sci Rep. 2019 Feb 28;9(1):3161. (PMID: 30816182)
Prog Brain Res. 2002;137:37-47. (PMID: 12440358)
Prog Brain Res. 2002;137:177-90. (PMID: 12440368)
Biomaterials. 2018 Oct;181:15-34. (PMID: 30071379)
J Mater Sci Mater Med. 2017 May;28(5):68. (PMID: 28357686)
Cell. 2006 Aug 25;126(4):677-89. (PMID: 16923388)
J Biomed Mater Res. 1986 Jul-Aug;20(6):773-84. (PMID: 3722214)
PLoS One. 2014 Feb 03;9(2):e86783. (PMID: 24498281)
J Transl Med. 2011 Mar 22;9:29. (PMID: 21418664)
Biomaterials. 2016 Jan;76:33-51. (PMID: 26517563)
Int J Nanomedicine. 2018 Oct 10;13:6265-6277. (PMID: 30349249)
Int J Mol Sci. 2023 Jun 16;24(12):. (PMID: 37373396)
J Mater Sci Mater Med. 2002 Sep;13(9):867-74. (PMID: 15348552)
Clin Epidemiol. 2014 Sep 23;6:309-31. (PMID: 25278785)
Biomaterials. 2010 May;31(14):3762-71. (PMID: 20149439)
Stem Cell Res. 2018 Oct;32:126-134. (PMID: 30278374)
Front Bioeng Biotechnol. 2016 Jul 18;4:62. (PMID: 27486578)
Sci Rep. 2015 Sep 28;5:14566. (PMID: 26411797)
Curr Pharm Biotechnol. 2015;16(1):26-34. (PMID: 25374028)
Neurochem Res. 2013 May;38(5):895-905. (PMID: 23462880)
Biomaterials. 2018 Dec;185:1-12. (PMID: 30216805)
Oxid Med Cell Longev. 2015;2015:610813. (PMID: 25834699)
J Biomed Mater Res. 2001 May;55(2):141-50. (PMID: 11255165)
Biomaterials. 2017 Sep;138:91-107. (PMID: 28554011)
Biomaterials. 2020 Feb;230:119642. (PMID: 31787332)
J Exp Biol. 2010 May;213(Pt 9):1513-20. (PMID: 20400636)
Neurosurg Focus. 2019 Mar 1;46(3):E10. (PMID: 30835679)
Biomaterials. 2000 Dec;21(24):2575-87. (PMID: 11071607)
Front Cell Neurosci. 2019 Jun 06;13:248. (PMID: 31244609)
Biomaterials. 2005 Feb;26(4):433-41. (PMID: 15275817)
Mol Neurobiol. 2020 Apr;57(4):2085-2100. (PMID: 31927725)
Adv Drug Deliv Rev. 2010 Jan 31;62(1):3-11. (PMID: 19800377)
Int J Mol Sci. 2021 Mar 29;22(7):. (PMID: 33805568)
Sci Rep. 2019 Apr 25;9(1):6402. (PMID: 31024032)
Mol Brain. 2015 Dec 01;8(1):79. (PMID: 26626025)
معلومات مُعتمدة: 2020/11667-0 São Paulo Research Foundation
فهرسة مساهمة: Keywords: biomaterial surface; cell replacement; hiPSCs; human induced pluripotent stem cells; spinal cord injury; tissue therapy
المشرفين على المادة: 0 (Biocompatible Materials)
تواريخ الأحداث: Date Created: 20230909 Date Completed: 20230911 Latest Revision: 20230911
رمز التحديث: 20230911
مُعرف محوري في PubMed: PMC10488158
DOI: 10.3390/ijms241713642
PMID: 37686446
قاعدة البيانات: MEDLINE
الوصف
تدمد:1422-0067
DOI:10.3390/ijms241713642