دورية أكاديمية
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Comparison and effect of moxibustion and acupuncture on Nogo/NgR signaling pathway in rats with cerebral ischemia/reperfusion injury.

التفاصيل البيبلوغرافية
العنوان: Comparison and effect of moxibustion and acupuncture on Nogo/NgR signaling pathway in rats with cerebral ischemia/reperfusion injury.
المؤلفون: Min YJ; School of Traditional Chinese Medicine, Nanchang Medical College, Nanchang, 330052, Jiangxi, China.; Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, 330006, Jiangxi, China., Yao HH; Shanghai Eighth People's Hospital, Shanghai, 200235, Shanghai, China., Wang L; School of Traditional Chinese Medicine, Nanchang Medical College, Nanchang, 330052, Jiangxi, China., Cheng LH; Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, 330006, Jiangxi, China., Hong ES; Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, 330006, Jiangxi, China.
المصدر: Journal of traditional and complementary medicine [J Tradit Complement Med] 2023 Mar 22; Vol. 13 (5), pp. 430-440. Date of Electronic Publication: 2023 Mar 22 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier B.V. on behalf of the Center for Food and Biomolecules, National Taiwan University Country of Publication: Netherlands NLM ID: 101605474 Publication Model: eCollection Cited Medium: Print ISSN: 2225-4110 (Print) Linking ISSN: 22254110 NLM ISO Abbreviation: J Tradit Complement Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: Amsterdam : Elsevier B.V. on behalf of the Center for Food and Biomolecules, National Taiwan University
Original Publication: Philadelphia, PA : [Taipei] : Wolters Kluwer Health, Medknow ; Committee on Chinese Medicine and Pharmacy
مستخلص: Background and Aim: In China, acupuncture and moxibustion have been used effectively to treat various diseases for thousands of years. However, the evidence for a difference in the efficacies of moxibustion and acupuncture in cerebral infarction treatment is scarce. We aimed to compare the effects of acupuncture and moxibustion treatment on the Nogo/NgR signaling pathway in rats with cerebral ischemia/reperfusion (I/R) injury.
Experimental Procedure: Eighty male SD rats were randomly divided into five groups, based on treatment received: sham surgery (sham group), middle cerebral artery occlusion (MCAO, MCAO group), MCAO and NEP(1-40) inhibitor injection (MCAO + block group), MCAO and moxibustion (MCAO + moxi group), and MCAO and minimal acupuncture (MCAO + MA group). Neurological status was evaluated before treatment, and cerebral infarction volume (IV) and neurological function; Nogo-A, NgR, p75NTR, and LINGO-1 expressions; and NgR and LINGO-1 co-expression were assessed after treatment.
Results and Conclusion: After treatment, barring Nogo-A mRNA and protein expression in the MCAO + block group, the Longa score and IV significantly decreased; Nogo-A, NgR, p75NTR, and LINGO-1 mRNA and protein expressions as well as NgR and LINGO-1 co-expression significantly decreased in cerebral tissues; whereas the BWT score increased (P < 0.01) in the MCAO + moxi group, compared with the MCAO group. Except for NgR and LINGO-1 protein expressions, there were no significant differences in the abovementioned parameters between rats that underwent acupuncture and moxibustion. Acupuncture and moxibustion have similar effects on Nogo/NgR signaling pathway inhibition after cerebral infarction.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2023 Center for Food and Biomolecules, National Taiwan University. Production and hosting by Elsevier Taiwan LLC.)
References: Evid Based Complement Alternat Med. 2021 Dec 3;2021:1907009. (PMID: 34899943)
Science. 1982 Aug 27;217(4562):855-7. (PMID: 7100929)
Neurorehabil Neural Repair. 2008 May-Jun;22(3):262-78. (PMID: 18056009)
Stroke. 1989 Jan;20(1):84-91. (PMID: 2643202)
Saudi J Biol Sci. 2021 Aug;28(8):4132-4136. (PMID: 34354392)
Am J Pathol. 2018 Jan;188(1):53-62. (PMID: 29030051)
Evid Based Complement Alternat Med. 2017;2017:7296353. (PMID: 29391874)
Neural Regen Res. 2018 Mar;13(3):477-483. (PMID: 29623933)
Evid Based Complement Alternat Med. 2022 Mar 12;2022:1451342. (PMID: 35313481)
Acupunct Med. 2017 Oct;35(5):360-365. (PMID: 28536255)
Evid Based Complement Alternat Med. 2018 Sep 17;2018:6030929. (PMID: 30310411)
Neuropsychiatr Dis Treat. 2023 Jan 25;19:233-245. (PMID: 36744205)
Evid Based Complement Alternat Med. 2013;2013:319734. (PMID: 23864884)
Nat Neurosci. 2004 Mar;7(3):221-8. (PMID: 14966521)
Aging (Albany NY). 2020 Jul 3;12(13):13187-13205. (PMID: 32620714)
Sci Rep. 2017 Oct 30;7(1):14362. (PMID: 29084954)
Neural Regen Res. 2018 Feb;13(2):257-264. (PMID: 29557375)
Neural Plast. 2021 Aug 19;2021:2662585. (PMID: 34456996)
Neuropsychiatr Dis Treat. 2019 Dec 13;15:3429-3442. (PMID: 31997879)
Sci Rep. 2016 Nov 18;6:36636. (PMID: 27857211)
Nature. 2002 Nov 7;420(6911):74-8. (PMID: 12422217)
Nature. 2002 May 30;417(6888):547-51. (PMID: 12037567)
Sci Rep. 2016 Nov 25;6:37846. (PMID: 27886247)
Brain. 2007 Nov;130(Pt 11):2951-61. (PMID: 17913768)
J Spinal Cord Med. 2021 May;44(3):364-374. (PMID: 31596180)
Zhen Ci Yan Jiu. 2019 Dec 25;44(12):867-72. (PMID: 31867904)
Evid Based Complement Alternat Med. 2020 Mar 18;2020:3872919. (PMID: 32256643)
Front Hum Neurosci. 2017 Nov 17;11:559. (PMID: 29204113)
فهرسة مساهمة: Keywords: Cerebral infarction; Myelin; Neural death; Neural restoration
تواريخ الأحداث: Date Created: 20230911 Latest Revision: 20230913
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10491986
DOI: 10.1016/j.jtcme.2023.03.006
PMID: 37693099
قاعدة البيانات: MEDLINE
الوصف
تدمد:2225-4110
DOI:10.1016/j.jtcme.2023.03.006