دورية أكاديمية
أعرض في EDS

Effects of COVID-19 or vaccines for SARS-COV-2 on sperm parameters: A systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Effects of COVID-19 or vaccines for SARS-COV-2 on sperm parameters: A systematic review and meta-analysis.
المؤلفون: Edele Santos D; Laboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Av. Universitária, 1105, Universitário, CEP 88806-000 Criciúma, SC, Brazil., Colonetti T; Laboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Av. Universitária, 1105, Universitário, CEP 88806-000 Criciúma, SC, Brazil., Rodrigues Uggioni ML; Laboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Av. Universitária, 1105, Universitário, CEP 88806-000 Criciúma, SC, Brazil., Rech P; Laboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Av. Universitária, 1105, Universitário, CEP 88806-000 Criciúma, SC, Brazil., Marcelino Baptista M; Laboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Av. Universitária, 1105, Universitário, CEP 88806-000 Criciúma, SC, Brazil., Medeiros LR; Laboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Av. Universitária, 1105, Universitário, CEP 88806-000 Criciúma, SC, Brazil., Grande AJ; Laboratory of Evidence-based Practice, Universidade Estadual de Mato Grosso do Sul, Av. Dom Antonio Barbosa (MS-080), 4.155, CEP 79115-898 Campo Grande, MS, Brazil; Graduate Program in Infectious and Parasitic Diseases, School of Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Brazil., Rosa MI; Laboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Av. Universitária, 1105, Universitário, CEP 88806-000 Criciúma, SC, Brazil. Electronic address: mir@unesc.net.
المصدر: Journal of reproductive immunology [J Reprod Immunol] 2023 Dec; Vol. 160, pp. 104140. Date of Electronic Publication: 2023 Sep 01.
نوع المنشور: Meta-Analysis; Systematic Review; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Ireland NLM ID: 8001906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7603 (Electronic) Linking ISSN: 01650378 NLM ISO Abbreviation: J Reprod Immunol Subsets: MEDLINE
أسماء مطبوعة: Publication: Limerick : Elsevier/North-Holland Biomedical Press
Original Publication: Amsterdam, Elsevier/North-Holland Biomedical Press.
مواضيع طبية MeSH: COVID-19* , Vaccines*, Male ; Humans ; SARS-CoV-2 ; COVID-19 Vaccines ; Cross-Sectional Studies ; Pandemics ; Semen ; Spermatozoa ; mRNA Vaccines
مستخلص: This systematic review and meta-analysis assessed the effects of SARS-Cov-2 and mRNA vaccines on male reproduction. We conducted a comprehensive search using terms such as "COVID-19," "vaccine," and "sperm parameters" on various electronic databases, including MEDLINE (PubMed), BVS (LILACS and others), Embase (Elsevier), and Cochrane Library. We included observational studies, including cohort, case-control, and cross-sectional studies. Of the 2054 records initially identified, we carefully examined 47 full-text articles and excluded 26 articles for specific reasons, ultimately including 21 studies for our analysis. Among these, 16 studies focused on assessing seminal parameters in patients with COVID-19, while five studies investigated the effects of COVID vaccines on seminal parameters. A meta-analysis of seminal parameters in men before and after the COVID-19 pandemic revealed significant differences in seminal concentration, progressive motility, total motility, and normal morphology. These findings indicate a positive impact of the analyzed parameters before the onset of COVID-19. However, the quality of the evidence was considered low. In contrast, a meta-analysis of five studies evaluating seminal parameters before and after the SARS-Cov-2 vaccine did not show any significant differences in total motility. This analysis, involving 256 men from four studies, provided low-quality evidence, suggesting that mRNA vaccines do not affect male reproduction. Overall, our findings suggest that seminal parameters exhibit considerable variability depending on specific outcomes and the study design. However, based on available evidence, it appears that mRNA vaccines do not have detrimental effects on male reproductive function.
Competing Interests: Declaration of Competing Interest The authors report no conflict of interest. This research did not receive any specific grant from any funding agency in the public, commercial, or not-for-profit sector.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: COVID-19; Sperm parameters; Systematic review; Vaccine
المشرفين على المادة: 0 (COVID-19 Vaccines)
0 (Vaccines)
0 (mRNA Vaccines)
تواريخ الأحداث: Date Created: 20230911 Date Completed: 20231205 Latest Revision: 20231228
رمز التحديث: 20231228
DOI: 10.1016/j.jri.2023.104140
PMID: 37696225
قاعدة البيانات: MEDLINE
الوصف
تدمد:1872-7603
DOI:10.1016/j.jri.2023.104140