دورية أكاديمية
أعرض في EDS

Prevention and post-exposure management of occupational exposure to Ebola virus.

التفاصيل البيبلوغرافية
العنوان: Prevention and post-exposure management of occupational exposure to Ebola virus.
المؤلفون: Moso MA; Victorian Infectious Diseases Reference Laboratory, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Infectious Diseases, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia. Electronic address: michael.moso@mh.org.au., Lim CK; Victorian Infectious Diseases Reference Laboratory, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Williams E; Victorian Infectious Diseases Reference Laboratory, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Marshall C; Department of Infectious Diseases, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., McCarthy J; Department of Infectious Diseases, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Williamson DA; Victorian Infectious Diseases Reference Laboratory, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Infectious Diseases, The University of Melbourne, The Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
المصدر: The Lancet. Infectious diseases [Lancet Infect Dis] 2024 Feb; Vol. 24 (2), pp. e93-e105. Date of Electronic Publication: 2023 Sep 15.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001-
مواضيع طبية MeSH: Ebolavirus* , Hemorrhagic Fever, Ebola*/prevention & control , Hemorrhagic Fever, Ebola*/epidemiology , Ebola Vaccines*, Humans ; Uganda/epidemiology ; Antibodies, Viral
مستخلص: There have been significant advances in the prevention and management of Ebola virus disease (EVD) caused by Zaire Ebola virus (ZEBOV), including the development of two effective vaccines, rVSV-ZEBOV and Ad26.ZEBOV/MVA-BN-Filo. In addition, ZEBOV monoclonal antibodies have become first-line therapy for EVD. However, the 2022-23 outbreak of Sudan Ebola virus (SUDV) in Uganda has highlighted the gap in current therapies and vaccines, whose efficacy is uncertain against non-ZEBOV species. Health-care and laboratory staff working in EVD treatment centres or Ebola virus diagnostic and research laboratories face unique risks relating to potential occupational exposure to Ebola viruses. Given the substantial morbidity and mortality associated with EVD, facilities should have strategies in place to manage occupational exposures, including consideration of post-exposure therapies. In this Review, we discuss currently available evidence for prevention and post-exposure prophylaxis of EVD, including therapies currently under evaluation for SUDV.
Competing Interests: Declaration of interests We declare no competing interests.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
المشرفين على المادة: 0 (Ebola Vaccines)
0 (Antibodies, Viral)
تواريخ الأحداث: Date Created: 20230918 Date Completed: 20240129 Latest Revision: 20240129
رمز التحديث: 20240129
DOI: 10.1016/S1473-3099(23)00376-6
PMID: 37722397
قاعدة البيانات: MEDLINE
الوصف
تدمد:1474-4457
DOI:10.1016/S1473-3099(23)00376-6