دورية أكاديمية
أعرض في EDS

Differences between cardiogenic shock related to acute decompensated heart failure and acute myocardial infarction.

التفاصيل البيبلوغرافية
العنوان: Differences between cardiogenic shock related to acute decompensated heart failure and acute myocardial infarction.
المؤلفون: Bertaina M; Division of Cardiology, San Giovanni Bosco Hospital, ASL Città di Torino, Turin, Italy., Morici N; IRCCS S. Maria Nascente-Fondazione Don Carlo Gnocchi ONLUS, Milan, Italy., Frea S; Intensive Cardiac Care Unit, Città della Salute e della Scienza di Torino, Turin, Italy., Garatti L; Cardiology Department and De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Briani M; Humanitas Research Hospital, IRCCS Rozzano, Milan, Italy., Sorini C; Division of Cardiology, Department of Medical Biotechnologies, University of Siena, Siena, Italy., Villanova L; Cardiology Department and De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Corrada E; Humanitas Research Hospital, IRCCS Rozzano, Milan, Italy., Sacco A; Cardiology Department and De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Moltrasio M; Centro Cardiologico Monzino IRCCS, Milan, Italy., Ravera A; Cardiology Department, Intensive Care Unit, S. Giovanni Di Dio e Ruggi D'Aragona Hospital, Salerno, Italy., Tedeschi M; Cardiology Department, Intensive Care Unit, S. Giovanni Di Dio e Ruggi D'Aragona Hospital, Salerno, Italy., Bertoldi L; Humanitas Research Hospital, IRCCS Rozzano, Milan, Italy., Lettino M; Cardiovascular Department, San Gerardo Hospital, ASST-Monza, Monza, Italy., Saia F; Cardiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Corsini A; Cardiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Camporotondo R; Intensive Cardiac Care Unit, Fondazione Policlinico San Matteo Hospital IRCCS, Pavia, Italy., Colombo CNJ; Intensive Cardiac Care Unit, Fondazione Policlinico San Matteo Hospital IRCCS, Pavia, Italy., Bertolin S; Cardiothoracic and Vascular Anesthesia and Intensive Care, AO SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy., Rota M; Units of Biostatistics and Biomathematics and Bioinformatics, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy., Oliva F; Cardiology Department and De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Iannaccone M; Division of Cardiology, San Giovanni Bosco Hospital, ASL Città di Torino, Turin, Italy., Valente S; Division of Cardiology, Department of Medical Biotechnologies, University of Siena, Siena, Italy., Pagnesi M; Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Cardiothoracic Department, Civil Hospitals, Brescia, Italy., Metra M; Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Cardiothoracic Department, Civil Hospitals, Brescia, Italy., Sionis A; Intensive Cardiac Care Unit, Cardiology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Marini M; Division of Cardiology and ICCU, Department of Cardiovascular Sciences, Ospedali Riuniti, Ancona, Italy., De Ferrari GM; Intensive Cardiac Care Unit, Città della Salute e della Scienza di Torino, Turin, Italy.; Department of Medical Sciences, University of Torino, Turin, Italy., Kapur NK; CardioVascular Center, Tufts Medical Center, Boston, MA, USA., Pappalardo F; Cardiothoracic and Vascular Anesthesia and Intensive Care, AO SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy., Tavazzi G; Department of Clinical-Surgical, Diagnostic and Paediatric Sciences, University of Pavia Italy, Pavia, Italy.; Anesthesia and Intensive Care, Fondazione Policlinico San Matteo Hospital IRCCS, Anestesia e Rianimazione I, Pavia, Italy.
المصدر: ESC heart failure [ESC Heart Fail] 2023 Dec; Vol. 10 (6), pp. 3472-3482. Date of Electronic Publication: 2023 Sep 18.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: John Wiley & Sons Ltd on behalf of the European Society of Cardiology Country of Publication: England NLM ID: 101669191 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2055-5822 (Electronic) Linking ISSN: 20555822 NLM ISO Abbreviation: ESC Heart Fail Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Oxford] : John Wiley & Sons Ltd on behalf of the European Society of Cardiology, [2014]-
مواضيع طبية MeSH: Myocardial Infarction*/therapy , Heart Failure*/complications , Heart Failure*/therapy , ST Elevation Myocardial Infarction*/complications, Humans ; Shock, Cardiogenic/etiology ; Shock, Cardiogenic/therapy ; Prospective Studies
مستخلص: Aims: The present analysis from the multicentre prospective Altshock-2 registry aims to better define clinical features, in-hospital course, and management of cardiogenic shock complicating acutely decompensated heart failure (ADHF-CS) as compared with that complicating acute myocardial infarction (AMI-CS).
Methods and Results: All patients with AMI-CS or ADHF-CS enrolled in the Altshock-2 registry between March 2020 and February 2022 were selected. The primary objective was the characterization of ADHF-CS patients as compared with AMI-CS. In-hospital length of stay and mortality were secondary endpoints. One-hundred-ninety of the 238 CS patients enrolled in the aforementioned period were considered for the present analysis: 101 AMI-CS (80% ST-elevated myocardial infarction and 20% non-ST-elevated myocardial infarction) and 89 ADHF-CS. As compared with AMI-CS, ADHF-CS patients were younger [63 (IQR 59-76) vs. 67 (IQR 54-73) years, P = 0.01], but presented with higher creatinine [1.6 (IQR 1.0-2.6) vs. 1.2 (IQR 1.0-1.4) mg/dL, P < 0.001], bilirubin [1.3 (IQR 0.9-2.3) vs. 0.6 (IQR 0.4-1.1) mg/dL, P = 0.01], and central venous pressure values [14 mmHg (IQR 8-12) vs. 10 mmHg (IQR 7-14),P = 0.01]. Norepinephrine was the most common catecholamine used in AMI-CS (79.3%), whereas epinephrine was used more commonly in ADHF-CS (65.5%); 75.8% vs. 46.6% received a temporary mechanical support in AMI-CS and ADHF-CS, respectively (P < 0.001). Length of hospital stay was longer in the latter [28 (IQR 13-48) vs. 17 (IQR 9-29) days, P = 0.001]. Heart replacement therapies were more frequently used in the ADHF-CS group (heart transplantation 13.5% vs. 0% and left ventricular assist device 11% vs. 2%, P < 0.01 and 0.01, respectively). In-hospital mortality was 41.1% (38.6% AMI-CS vs. 43.8% ADHF-CS, P = 0.5).
Conclusions: ADHF-CS is characterized by a higher prevalence of end-organ and biventricular dysfunction at presentation, a longer hospital length of stay, and higher need of heart replacement therapies when compared with AMI-CS. In-hospital mortality was similar between the two aetiologies. Our data warrant development of new management protocols focused on CS aetiology.
(© 2023 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.)
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فهرسة مساهمة: Keywords: Cardiogenic shock; Heart failure; Mortality; Myocardial infarction
تواريخ الأحداث: Date Created: 20230918 Date Completed: 20231129 Latest Revision: 20231130
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10682868
DOI: 10.1002/ehf2.14510
PMID: 37723131
قاعدة البيانات: MEDLINE
الوصف
تدمد:2055-5822
DOI:10.1002/ehf2.14510