دورية أكاديمية
أعرض في EDS

Evaluation of Quantitative Dual-Energy Computed Tomography Parameters for Differentiation of Parotid Gland Tumors.

التفاصيل البيبلوغرافية
العنوان: Evaluation of Quantitative Dual-Energy Computed Tomography Parameters for Differentiation of Parotid Gland Tumors.
المؤلفون: Wang Y; Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China (Y.W., H.H., Y.J., Y.S., L.Y., G.S., L.Y., R.H., X.D.)., Hu H; Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China (Y.W., H.H., Y.J., Y.S., L.Y., G.S., L.Y., R.H., X.D.)., Ban X; Department of Radiology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou 510060, Guangdong, China (X.B.)., Jiang Y; Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China (Y.W., H.H., Y.J., Y.S., L.Y., G.S., L.Y., R.H., X.D.)., Su Y; Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China (Y.W., H.H., Y.J., Y.S., L.Y., G.S., L.Y., R.H., X.D.)., Yang L; Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China (Y.W., H.H., Y.J., Y.S., L.Y., G.S., L.Y., R.H., X.D.)., Shi G; Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China (Y.W., H.H., Y.J., Y.S., L.Y., G.S., L.Y., R.H., X.D.); Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, Guangdong, China (G.S., X.D.)., Yang L; Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China (Y.W., H.H., Y.J., Y.S., L.Y., G.S., L.Y., R.H., X.D.)., Han R; Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China (Y.W., H.H., Y.J., Y.S., L.Y., G.S., L.Y., R.H., X.D.)., Duan X; Department of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong, China (Y.W., H.H., Y.J., Y.S., L.Y., G.S., L.Y., R.H., X.D.); Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, Guangdong, China (G.S., X.D.). Electronic address: duanxh5@mail.sysu.edu.cn.
المصدر: Academic radiology [Acad Radiol] 2024 May; Vol. 31 (5), pp. 2027-2038. Date of Electronic Publication: 2023 Sep 18.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Association Of University Radiologists Country of Publication: United States NLM ID: 9440159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4046 (Electronic) Linking ISSN: 10766332 NLM ISO Abbreviation: Acad Radiol Subsets: MEDLINE
أسماء مطبوعة: Publication: Reston Va : Association Of University Radiologists
Original Publication: Reston, VA : Association of University Radiologists, c1994-
مواضيع طبية MeSH: Parotid Neoplasms*/diagnostic imaging , Tomography, X-Ray Computed*/methods , Radiography, Dual-Energy Scanned Projection*/methods, Humans ; Male ; Female ; Middle Aged ; Diagnosis, Differential ; Adult ; Aged ; Sensitivity and Specificity ; Adenolymphoma/diagnostic imaging ; Aged, 80 and over ; Adenoma, Pleomorphic/diagnostic imaging ; Contrast Media ; Young Adult ; Adolescent ; Retrospective Studies
مستخلص: Rationale and Objectives: To assess the diagnostic performance of quantitative parameters from dual-energy CT (DECT) in differentiating parotid gland tumors (PGTs).
Materials and Methods: 101 patients with 108 pathologically proved PGTs were enrolled and classified into four groups: pleomorphic adenomas (PAs), warthin tumors (WTs), other benign tumors (OBTs), and malignant tumors (MTs). Conventional CT attenuation and DECT quantitative parameters, including iodine concentration (IC), normalized iodine concentration (NIC), effective atomic number (Z eff ), electron density (Rho), double energy index (DEI), and the slope of the spectral Hounsfield unit curve (λ HU ), were obtained and compared between benign tumors (BTs) and MTs, and further compared among the four subgroups. Logistic regression analysis was used to assess the independent parameters and the receiver operating characteristic (ROC) curves were used to analyze the diagnostic performance.
Results: Attenuation, Z eff , DEI, IC, NIC, and λ HU in the arterial phase (AP) and venous phase (VP) were higher in MTs than in BTs (p < 0.001-0.047). λ HU in VP and Z eff in AP were independent predictors with an area under the curve (AUC) of 0.84 after the combination. Furthermore, attenuation, Z eff , DEI, IC, NIC, and λ HU in the AP and VP of MTs were higher than those of PAs (p < 0.001-0.047). Z eff and NIC in AP and λ HU in VP were independent predictors with an AUC of 0.93 after the combination. Attenuation and Rho in the precontrast phase; attenuation, Rho, Z eff , DEI, IC, NIC, and λ HU in AP; and the Rho in the VP of PAs were lower than those of WTs (p < 0.001-0.03). Rho in the precontrast phase and attenuation in AP were independent predictors with an AUC of 0.89 after the combination. MTs demonstrated higher Z eff , DEI, IC, NIC, and λ HU in VP and lower Rho in the precontrast phase compared with WTs (p < 0.001-0.04); but no independent predictors were found.
Conclusion: DECT quantitative parameters can help to differentiate PGTs.
Competing Interests: Declaration of Competing Interest There are no conflicts of interest.
(Copyright © 2024 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Diagnosis; Dual-energy computed tomography; Parotid gland; Parotid neoplasms
المشرفين على المادة: 0 (Contrast Media)
تواريخ الأحداث: Date Created: 20230920 Date Completed: 20240509 Latest Revision: 20240613
رمز التحديث: 20240614
DOI: 10.1016/j.acra.2023.08.024
PMID: 37730491
قاعدة البيانات: MEDLINE
الوصف
تدمد:1878-4046
DOI:10.1016/j.acra.2023.08.024