دورية أكاديمية
Endoscopic diagnosis of a neuroendocrine neoplasm inside a Meckel's diverticulum: a capsule endoscopy finding.
| العنوان: | Endoscopic diagnosis of a neuroendocrine neoplasm inside a Meckel's diverticulum: a capsule endoscopy finding. |
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| المؤلفون: | Urpí-Ferreruela M; Endoscopy Unit, Gastroenterology Department, Institut Clinic de Malalties Digestives i Metabòliques, Clinic Hospital of Barcelona, Barcelona, Spain., López-Balaguer JM; Endoscopy Unit, Teknon Medical Center, Barcelona, Spain., Bilbao AM; Endoscopy Unit, Teknon Medical Center, Barcelona, Spain., Rimer GC; Endoscopy Unit, Gastroenterology Department, Institut Clinic de Malalties Digestives i Metabòliques, Clinic Hospital of Barcelona, Barcelona, Spain., González-Suárez B; Endoscopy Unit, Gastroenterology Department, Institut Clinic de Malalties Digestives i Metabòliques, Clinic Hospital of Barcelona, Barcelona, Spain. |
| المصدر: | Gastrointestinal endoscopy [Gastrointest Endosc] 2024 Feb; Vol. 99 (2), pp. 283-284. Date of Electronic Publication: 2023 Sep 22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mosby Yearbook Country of Publication: United States NLM ID: 0010505 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6779 (Electronic) Linking ISSN: 00165107 NLM ISO Abbreviation: Gastrointest Endosc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: St Louis, Mo : Mosby Yearbook Original Publication: Denver. |
| مواضيع طبية MeSH: | Meckel Diverticulum*/diagnosis , Meckel Diverticulum*/diagnostic imaging , Capsule Endoscopy* , Neuroendocrine Tumors*/complications , Neuroendocrine Tumors*/diagnostic imaging , Neuroendocrine Tumors*/surgery, Humans ; Gastrointestinal Hemorrhage/diagnosis |
| مستخلص: | Competing Interests: Disclosure All authors disclosed no financial relationships. Commentary With the prevalence of approximately 2%, Meckel’s diverticulum is the most common congenital anomaly of the GI tract. The majority of cases remain asymptomatic; however, Meckel’s diverticulum is associated with a slight increased risk of malignancy. The most common malignant tumor within Meckel’s diverticulum is neuroendocrine tumor (NET), followed by adenocarcinoma, GI stromal tumor, sarcoma, and lymphoma. It has been hypothesized that the incidence of Meckel’s diverticulum–associated malignancy increases with age. This phenomenon has been seen proportionally higher in male patients. The most common symptoms of NETs within the Meckel’s diverticulum include abdominal pain, diarrhea, weight loss, intermittent GI bleeding, and bowel obstruction, although the majority of cases are asymptomatic and are detected incidentally. NETs within a Meckel’s diverticulum are associated with a high rate (24% to 75%) of metastasis (nodal and liver metastasis) at the time of diagnosis. This aggressive tumor behavior is more similar to small-bowel NETs as opposed to appendiceal NETs. Owing to a higher tendency for early metastasis in smal-bowel NETs, lymphadenectomy in addition to bowel resection is recommended. Late-onset metastasis after only bowel resection in NETs within Meckel’s diverticulum has been reported. In cases without lymphadenectomy, perhaps close interval imaging surveillance should be considered. Small NETs, such as in this case, could be easily missed, and lifesaving treatment could be delayed inadvertently. This case is a great example of “dig deeper” in those small-bowel capsule endoscopy images! Tara Keihanian, MD, MPH, Assistant Professor, Division of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA Amy Tyberg, MD, FASGE, FACG, Associate Editor for Focal Points |
| تواريخ الأحداث: | Date Created: 20230923 Date Completed: 20240122 Latest Revision: 20240524 |
| رمز التحديث: | 20240525 |
| DOI: | 10.1016/j.gie.2023.09.013 |
| PMID: | 37741295 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1097-6779 |
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| DOI: | 10.1016/j.gie.2023.09.013 |