دورية أكاديمية
Association of respiratory virus types with clinical features in bronchiolitis: Implications for virus testing strategies. A systematic review and meta-analysis.
| العنوان: | Association of respiratory virus types with clinical features in bronchiolitis: Implications for virus testing strategies. A systematic review and meta-analysis. |
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| المؤلفون: | Ambrożej D; Department of Pediatric Pneumonology and Allergy, Medical University of Warsaw, Warsaw, Poland; Doctoral School, Medical University of Warsaw, Warsaw, Poland., Orzołek I; Department of Pediatric Pneumonology and Allergy, Medical University of Warsaw, Warsaw, Poland., Makrinioti H; Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Castro-Rodriguez JA; Department of Pediatric Pulmonology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Camargo CA Jr; Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Hasegawa K; Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Papadopoulos NG; Allergy and Clinical Immunology Unit, 2nd Paediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece; Division of Evolution and Genomic Sciences, University of Manchester, Manchester, United Kingdom., Gern JE; Department of Paediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, Wisconsin, WI, USA., Nino G; Division of Pediatric Pulmonary and Sleep Medicine, Children's National Hospital, Washington, District of Columbia, USA; Department of Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA., Vicente Ribeiro Ferreira da Silva Filho L; Instituto da Criança e do Adolescente, Hospital das Clínicas, University of São Paulo Medical School (USP), Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Takeyama A; Department of Pediatrics, Soma General Hospital, Fukushima, Japan., Üzüm Ö; Department of Pediatric Diseases, Tepecik Training and Research Hospital, University of Health Sciences, Izmir, Turkey., Adamiec A; Department of Pediatric Pneumonology and Allergy, Medical University of Warsaw, Warsaw, Poland; Doctoral School, Medical University of Warsaw, Warsaw, Poland., Ruszczyński M; Department of Pediatrics, Medical University of Warsaw, Warsaw, Poland., Jartti T; Department of Pediatrics, Turku University Hospital and University of Turku, Turku, Finland; Department of Pediatrics, University of Oulu, Oulu, Finland., Feleszko W; Department of Pediatric Pneumonology and Allergy, Medical University of Warsaw, Warsaw, Poland. Electronic address: wojciech.feleszko@wum.edu.pl. |
| المصدر: | Paediatric respiratory reviews [Paediatr Respir Rev] 2024 Mar; Vol. 49, pp. 34-42. Date of Electronic Publication: 2023 Sep 17. |
| نوع المنشور: | Meta-Analysis; Systematic Review; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: W.B. Saunders Country of Publication: England NLM ID: 100898941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-0550 (Electronic) Linking ISSN: 15260542 NLM ISO Abbreviation: Paediatr Respir Rev |
| أسماء مطبوعة: | Original Publication: London : W.B. Saunders, c2000- |
| مواضيع طبية MeSH: | Bronchiolitis, Viral*/diagnosis , Bronchiolitis, Viral*/pathology , Bronchiolitis, Viral*/virology , Picornaviridae Infections*/diagnosis , Picornaviridae Infections*/pathology , Picornaviridae Infections*/virology , Respiratory Syncytial Virus Infections*/diagnosis , Respiratory Syncytial Virus Infections*/pathology , Respiratory Syncytial Virus Infections*/virology, Humans ; Eczema ; Oxygen Inhalation Therapy ; Respiratory Sounds ; Rhinovirus ; Respiratory Syncytial Viruses |
| مستخلص: | Background: Bronchiolitis is a leading cause of infant hospitalization, linked to respiratory syncytial virus (RSV) and rhinovirus (RV). Guidelines lack specific viral testing for bronchiolitis management. To establish effective management strategies, it is crucial to assess whether specific respiratory virus types are correlated with distinct examination features. Methods: Through a systematic search of three databases, 21 studies were qualitatively analyzed, with 18 used for meta-analysis. Various outcomes like wheezing on auscultation, fever, atopic traits, and infection severity were evaluated. Results: RSV-positive bronchiolitis was associated with a higher need for oxygen supplementation (OR 1.78, 95% CI 1.04-3.02) in 5 studies, while RV-positive bronchiolitis was more frequently linked to personal history of eczema (OR 0.60, 95% CI 0.41-0.88) in 6 studies. No significant differences were observed in the other outcomes examined. Conclusions: Bronchiolitis caused by RSV or RV presents with similar clinical features. Despite the associations between RSV-positive bronchiolitis and need for oxygen supplementation, and RV-positive bronchiolitis and a history of eczema, our study shows that viral etiology of bronchiolitis cannot be determined solely based on clinical presentation. Tailored management strategies, informed by accurate viral testing, seem crucial in clinical practice for enhancing patient outcomes in severe bronchiolitis. Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Bronchiolitis; Infant; Respiratory syncytial virus; Rhinovirus; Systematic review; Wheeze |
| تواريخ الأحداث: | Date Created: 20230924 Date Completed: 20240807 Latest Revision: 20240823 |
| رمز التحديث: | 20240823 |
| DOI: | 10.1016/j.prrv.2023.09.003 |
| PMID: | 37743159 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1526-0550 |
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| DOI: | 10.1016/j.prrv.2023.09.003 |