دورية أكاديمية
A Comparison of Self-reported Condomless Sex and Yc-DNA Biomarker Data from Young Women Engaged in High Risk Sexual Activity in Kampala, Uganda.
| العنوان: | A Comparison of Self-reported Condomless Sex and Yc-DNA Biomarker Data from Young Women Engaged in High Risk Sexual Activity in Kampala, Uganda. |
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| المؤلفون: | Boering P; London School of Hygiene and Tropical Medicine, London, UK., Seeley J; London School of Hygiene and Tropical Medicine, London, UK. janet.seeley@lshtm.ac.uk.; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda. janet.seeley@lshtm.ac.uk., Buule J; Uganda Virus Research Institute, Entebbe, Uganda., Kamacooko O; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., King R; University of California, San Francisco, CA, USA.; INSERM, 60 Rue de Navacelles, 34090, Montpellier, France. |
| المصدر: | AIDS and behavior [AIDS Behav] 2024 Jan; Vol. 28 (1), pp. 320-331. Date of Electronic Publication: 2023 Sep 26. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 9712133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-3254 (Electronic) Linking ISSN: 10907165 NLM ISO Abbreviation: AIDS Behav Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2005- : New York, NY : Springer Science + Business Media Original Publication: New York, NY : Plenum Press, 1997- |
| مواضيع طبية MeSH: | Unsafe Sex* , HIV Infections*/diagnosis , HIV Infections*/epidemiology , HIV Infections*/prevention & control, Humans ; Female ; Self Report ; Uganda/epidemiology ; Sexual Behavior ; DNA/analysis ; Biomarkers ; Sexual Partners ; Condoms |
| مستخلص: | Reporting of condom-use can limit researchers' understanding of high-risk sexual behaviours. We compared self-reported condom-use with the Yc-DNA biomarker data and investigated potential factors influencing participation in, and reporting of, sexual behaviours. Self-reported data were collected using Audio Computer Assisted Self Interviews (ACASI) and samples for Yc-DNA biomarker were collected using self-administered and health worker-collected vaginal swabs from 644 women (aged 15-24 years) who were not living with HIV. Yc-DNA results and interview data were compared using McNemar-Bowker Analysis and Cohen's Kappa. Test statistics for Yc-DNA biomarker were calculated. Log Binomial models for Yc-DNA and self-reported results were conducted to assess for association. We found strong evidence (p < 0.001) for a difference between Yc-DNA and self-reported results. 13.7% of participants reported consistent condom-use with all partners, regardless of HIV status. Self-reported condom-use was discordant in 50.0% (n = 206) of cases, when compared to Yc-DNA results. Positive Yc-DNA results were found to be associated with older age (RR 1.36; 95%CI 1.04, 1.76 p = 0.023). Self-reported condom-use with partners with unknown HIV status was associated with higher education (RR 0.76; 95%CI 0.58,0.99 p = 0.043). Sensitivity analysis did not determine difference between methods for controlling for missing data. We found significant under-reporting of condomless sex in the self-reported data when compared to Yc-DNA results. (© 2023. The Author(s).) |
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| معلومات مُعتمدة: | R01 MH109337 United States MH NIMH NIH HHS; R01MH09337 United States NH NIH HHS; 00 United Kingdom MRC_ Medical Research Council; R01MH09337 United States NH NIH HHS |
| فهرسة مساهمة: | Keywords: Biomarkers; Condomless Sex; HIV Prevention; Sex work; Social desirability bias |
| المشرفين على المادة: | 9007-49-2 (DNA) 0 (Biomarkers) |
| تواريخ الأحداث: | Date Created: 20230926 Date Completed: 20240123 Latest Revision: 20240125 |
| رمز التحديث: | 20240125 |
| مُعرف محوري في PubMed: | PMC10803388 |
| DOI: | 10.1007/s10461-023-04177-y |
| PMID: | 37751111 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1573-3254 |
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| DOI: | 10.1007/s10461-023-04177-y |