دورية أكاديمية
Fractal analysis is a useful tool for evaluating prostate tissue remodeling caused by ethanol consumption and androgen therapy.
| العنوان: | Fractal analysis is a useful tool for evaluating prostate tissue remodeling caused by ethanol consumption and androgen therapy. |
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| المؤلفون: | Lima BJP; Programa de Pós-Graduação em Ciências da Saúde, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil., de Oliveira GRL; Programa de Pós-Graduação em Ciência Animal, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil., Sousa TC; Programa de Pós-Graduação em Ciência Animal, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil., de Aquino AM; Departmento de Biologia Estrutural e Funcional, Instituto de Biociências de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil., Hinokuma KD; Programa de Pós-Graduação em Ciência Animal, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil., Ricardo MLS; Programa de Pós-Graduação em Ciência Animal, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil., Scarano WR; Departmento de Biologia Estrutural e Funcional, Instituto de Biociências de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil., Castilho ACS; Programa de Pós-Graduação em Ciência Animal, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil., Pacagnelli FL; Programa de Pós-Graduação em Ciências da Saúde, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil.; Programa de Pós-Graduação em Ciência Animal, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil., Martinez FE; Departmento de Biologia Estrutural e Funcional, Instituto de Biociências de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil., Mendes LO; Programa de Pós-Graduação em Ciências da Saúde, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil.; Programa de Pós-Graduação em Ciência Animal, Universidade do Oeste Paulista, Presidente Prudente, SP, Brasil. |
| المصدر: | Animal reproduction [Anim Reprod] 2023 Sep 18; Vol. 20 (3), pp. e20230072. Date of Electronic Publication: 2023 Sep 18 (Print Publication: 2023). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Colégio Brasileiro de Reprodução Animal Country of Publication: Brazil NLM ID: 101272804 Publication Model: eCollection Cited Medium: Internet ISSN: 1984-3143 (Electronic) Linking ISSN: 18069614 NLM ISO Abbreviation: Anim Reprod Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Belo Horizonte, MG, Brazil : Colégio Brasileiro de Reprodução Animal, [2004]- |
| مستخلص: | Alcohol has been widely consumed for centuries and is linked to the aggravation of diseases. Several studies have shown that excessive consumption of ethanol results in morphophysiological changes in the male reproductive system. One of the effects of ethanol is the decrease in testosterone concentration and hormonal therapies are an alternative to minimize the changes resulting from chronic alcoholism. Qualitative studies were commonly carried out to evaluate the male histopathological alterations resulting from ethanol consumption, being necessary quantitative and non-subjective techniques. This study analyzes the importance of fractal analysis as a useful tool to identify and quantify tissue remodeling in rats submitted to ethanol consumption and hormone therapy with testosterone. Prostate of animals submitted to chronic ethanol consumption showed tissue disorganization, which was confirmed by an increasing of fractal dimension. Regarding the prostatic stroma, collagen fractal dimension and quantification revealed lower values in animals that were only submitted to androgen therapy. Thus, we can conclude that the fractal analysis was a useful tool to quantify tissue changes caused by ethanol consumption and androgen therapy. Competing Interests: Conflicts of interest: The authors have no conflict of interest to declare. |
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| فهرسة مساهمة: | Keywords: chronic alcoholism; fractal dimension; prostate; testosterone |
| تواريخ الأحداث: | Date Created: 20231005 Latest Revision: 20231006 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC10546910 |
| DOI: | 10.1590/1984-3143-AR2023-0072 |
| PMID: | 37795198 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1984-3143 |
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| DOI: | 10.1590/1984-3143-AR2023-0072 |