دورية أكاديمية

Estrogens and the risk of breast cancer: A narrative review of literature.

التفاصيل البيبلوغرافية
العنوان: Estrogens and the risk of breast cancer: A narrative review of literature.
المؤلفون: Al-Shami K; Faculty of Medicine, Yarmouk University, P.O Box 566, 21163, Irbid, Jordan., Awadi S; Faculty of Medicine, Yarmouk University, P.O Box 566, 21163, Irbid, Jordan., Khamees A; Faculty of Medicine, Yarmouk University, P.O Box 566, 21163, Irbid, Jordan.; Department of General Surgery, King Hussein Cancer Center, Amman, 11941, Jordan., Alsheikh AM; Faculty of Medicine, Yarmouk University, P.O Box 566, 21163, Irbid, Jordan., Al-Sharif S; Faculty of Medicine, Yarmouk University, P.O Box 566, 21163, Irbid, Jordan., Ala' Bereshy R; Faculty of Medicine, Yarmouk University, P.O Box 566, 21163, Irbid, Jordan., Al-Eitan SF; Faculty of Medicine, Yarmouk University, P.O Box 566, 21163, Irbid, Jordan., Banikhaled SH; Faculty of Medicine, Yarmouk University, P.O Box 566, 21163, Irbid, Jordan., Al-Qudimat AR; Department of Public Health, College of Health Sciences, QU-Health, Qatar University, Doha, 2713, Qatar.; Surgical Research Section, Department of Surgery, Hamad Medical Corporation, Doha, Qatar., Al-Zoubi RM; Surgical Research Section, Department of Surgery, Hamad Medical Corporation, Doha, Qatar.; Department of Biomedical Sciences, College of Health Sciences, QU-Health, Qatar University, Doha, 2713, Qatar.; Department of Chemistry, Jordan University of Science and Technology, P.O.Box 3030, Irbid, 22110, Jordan., Al Zoubi MS; Faculty of Medicine, Yarmouk University, P.O Box 566, 21163, Irbid, Jordan.
المصدر: Heliyon [Heliyon] 2023 Sep 17; Vol. 9 (9), pp. e20224. Date of Electronic Publication: 2023 Sep 17 (Print Publication: 2023).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101672560 Publication Model: eCollection Cited Medium: Print ISSN: 2405-8440 (Print) Linking ISSN: 24058440 NLM ISO Abbreviation: Heliyon Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: London : Elsevier Ltd, [2015]-
مستخلص: In female mammals, the development and regulation of the reproductive system and non-reproductive system are significantly influenced by estrogens (oestrogens). In addition, lipid metabolism is another physiological role of estrogens. Estrogens act through different types of receptors to introduce signals to the target cell by affecting many estrogen response elements. Breast cancer is considered mostly a hormone-dependent disease. Approximately 70% of breast cancers express progesterone receptors and/or estrogen receptors, and they are a good marker for cancer prognosis. This review will discuss estrogen metabolism and the interaction of estrogen metabolites with breast cancer. The carcinogenic role of estrogen is discussed in light of both conventional and atypical cancers susceptible to hormones, such as prostate, endometrial, and lung cancer, as we examine how estrogen contributes to the formation and activation of breast cancer. In addition, this review will discuss other factors that can be associated with estrogen-driven breast cancer.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2023 The Authors.)
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فهرسة مساهمة: Keywords: Breast cancer; ER; Estrogen; Oestrogen; Risk
تواريخ الأحداث: Date Created: 20231009 Latest Revision: 20231018
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10559995
DOI: 10.1016/j.heliyon.2023.e20224
PMID: 37809638
قاعدة البيانات: MEDLINE
الوصف
تدمد:2405-8440
DOI:10.1016/j.heliyon.2023.e20224