دورية أكاديمية
Synthesis, processing, and secretion of rat immunoglobulin E made in Xenopus oocytes.
| العنوان: | Synthesis, processing, and secretion of rat immunoglobulin E made in Xenopus oocytes. |
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| المؤلفون: | Lund T, Bravo R, Johansen HR, Zeuthen J, Vuust J |
| المصدر: | FEBS letters [FEBS Lett] 1986 Nov 24; Vol. 208 (2), pp. 369-72. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print Cited Medium: Print ISSN: 0014-5793 (Print) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2016- : West Sussex : John Wiley & Sons Ltd. Original Publication: Amsterdam, North-Holland on behalf of the Federation of European Biochemical Societies. |
| مواضيع طبية MeSH: | Immunoglobulin E/*biosynthesis, Animals ; Glycosylation ; Immunoglobulin E/metabolism ; Microinjections ; Molecular Weight ; Oocytes/metabolism ; Protein Biosynthesis ; Protein Processing, Post-Translational ; RNA, Messenger/genetics ; Rats ; Xenopus laevis |
| مستخلص: | Rat immunoglobulin E (IgE) synthesized in Xenopus laevis oocytes, injected with rat plasmacytoma mRNA, was analysed by specific immunoprecipitation and SDS-polyacrylamide gel electrophoresis under reducing as well as non-reducing conditions. The results indicate that the oocytes will translate and correctly process the rat IgE heavy and light chains, resulting in secretion of a correctly assembled, normal immunoglobulin molecule. The normal, extensive glycosylation of the IgE heavy chain (e-chain) is faithfully carried out by the oocytes; therefore, this posttranslational modification is apparently of an unspecific nature, and does not depend upon a mechanism specific for plasma cells. |
| المشرفين على المادة: | 0 (RNA, Messenger) 37341-29-0 (Immunoglobulin E) |
| تواريخ الأحداث: | Date Created: 19861124 Date Completed: 19870107 Latest Revision: 20190621 |
| رمز التحديث: | 20221208 |
| DOI: | 10.1016/0014-5793(86)81051-1 |
| PMID: | 3780973 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0014-5793 |
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| DOI: | 10.1016/0014-5793(86)81051-1 |