دورية أكاديمية
The effects of clinicopathological and imaging findings on recurrence and survival in mammary Paget's disease.
العنوان: | The effects of clinicopathological and imaging findings on recurrence and survival in mammary Paget's disease. |
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المؤلفون: | Baysal H; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Erol CI; Department of General Surgery, Erzurum City Hospital, Erzurum, Turkiye., Baysal B; Department of Radiology, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Ozemir IA; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Ozsoy MS; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Buyuker F; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Kir G; Department of Pathology, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Alimoglu O; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye. |
المصدر: | Northern clinics of Istanbul [North Clin Istanb] 2023 Sep 27; Vol. 10 (5), pp. 541-549. Date of Electronic Publication: 2023 Sep 27 (Print Publication: 2023). |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Kare Publishing Country of Publication: Turkey NLM ID: 101684520 Publication Model: eCollection Cited Medium: Internet ISSN: 2536-4553 (Electronic) Linking ISSN: 25364553 NLM ISO Abbreviation: North Clin Istanb Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Istanbul, Turkey : Kare Publishing, [2014]- |
مستخلص: | Objective: Mammary Paget's disease (MPD) is a rare presentation type of breast cancer. The aim of this study was to evaluate the clinicopathological and imaging features affecting the invasive component, loco-regional recurrence, prognosis, and survival of MPD. Methods: Patients who had undergone surgery due to MPD in a 10-year period were included. Parameters including mammography and magnetic resonance imaging (MRI) findings, tumor stage, molecular subtype, axillary involvement, presence of invasive carcinoma, loco-regional recurrence, overall survival (OS), and disease-free survival (DFS) were recorded and statistically analyzed. P<0.05 was determined as statistically significant. Results: The study group consisted of 49 women with a mean age of 67.05±14.43 (range: 23-90) years. There was a significant association between the presence of invasive carcinoma and a mass lesion in the MRI (p=0.002). The frequency of sentinel lymph node (SLN) metastasis was significantly higher in patients with multicentric tumors (p=0.029; p<0.05). Locoregional recurrence and distant metastasis were significantly more frequent in patients with axillary involvement (p=0.0336; p<0.05). The mean DFS was 115.02±7.28 months, while the mean OS was 119.29±6.57 months. Conclusion: The presence of a mass lesion on MRI was determined to be significant in recognizing invasive carcinoma in MPD. The rate of SLN metastasis was higher in patients with multicentric tumors than in patients with unifocal tumors. Axillary involvement was associated with impaired DFS. Competing Interests: No conflict of interest was declared by the authors. (© Copyright 2023 by Istanbul Provincial Directorate of Health.) |
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فهرسة مساهمة: | Keywords: Breast neoplasms; local recurrence; pathology; radiology; survival |
تواريخ الأحداث: | Date Created: 20231013 Latest Revision: 20231031 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC10565753 |
DOI: | 10.14744/nci.2023.77010 |
PMID: | 37829736 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2536-4553 |
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DOI: | 10.14744/nci.2023.77010 |