دورية أكاديمية
أعرض في EDS

The effects of clinicopathological and imaging findings on recurrence and survival in mammary Paget's disease.

التفاصيل البيبلوغرافية
العنوان: The effects of clinicopathological and imaging findings on recurrence and survival in mammary Paget's disease.
المؤلفون: Baysal H; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Erol CI; Department of General Surgery, Erzurum City Hospital, Erzurum, Turkiye., Baysal B; Department of Radiology, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Ozemir IA; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Ozsoy MS; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Buyuker F; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Kir G; Department of Pathology, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye., Alimoglu O; Department of General Surgery, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Turkiye.
المصدر: Northern clinics of Istanbul [North Clin Istanb] 2023 Sep 27; Vol. 10 (5), pp. 541-549. Date of Electronic Publication: 2023 Sep 27 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Kare Publishing Country of Publication: Turkey NLM ID: 101684520 Publication Model: eCollection Cited Medium: Internet ISSN: 2536-4553 (Electronic) Linking ISSN: 25364553 NLM ISO Abbreviation: North Clin Istanb Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Istanbul, Turkey : Kare Publishing, [2014]-
مستخلص: Objective: Mammary Paget's disease (MPD) is a rare presentation type of breast cancer. The aim of this study was to evaluate the clinicopathological and imaging features affecting the invasive component, loco-regional recurrence, prognosis, and survival of MPD.
Methods: Patients who had undergone surgery due to MPD in a 10-year period were included. Parameters including mammography and magnetic resonance imaging (MRI) findings, tumor stage, molecular subtype, axillary involvement, presence of invasive carcinoma, loco-regional recurrence, overall survival (OS), and disease-free survival (DFS) were recorded and statistically analyzed. P<0.05 was determined as statistically significant.
Results: The study group consisted of 49 women with a mean age of 67.05±14.43 (range: 23-90) years. There was a significant association between the presence of invasive carcinoma and a mass lesion in the MRI (p=0.002). The frequency of sentinel lymph node (SLN) metastasis was significantly higher in patients with multicentric tumors (p=0.029; p<0.05). Locoregional recurrence and distant metastasis were significantly more frequent in patients with axillary involvement (p=0.0336; p<0.05). The mean DFS was 115.02±7.28 months, while the mean OS was 119.29±6.57 months.
Conclusion: The presence of a mass lesion on MRI was determined to be significant in recognizing invasive carcinoma in MPD. The rate of SLN metastasis was higher in patients with multicentric tumors than in patients with unifocal tumors. Axillary involvement was associated with impaired DFS.
Competing Interests: No conflict of interest was declared by the authors.
(© Copyright 2023 by Istanbul Provincial Directorate of Health.)
References: Breast Cancer Res Treat. 2007 Apr;102(2):137-42. (PMID: 17028984)
Gland Surg. 2022 Jan;11(1):207-215. (PMID: 35242682)
Radiology. 1993 Oct;189(1):89-94. (PMID: 8396786)
Exp Biol Med (Maywood). 2022 Feb;247(3):187-199. (PMID: 34842487)
Int J Clin Exp Med. 2015 Oct 15;8(10):19616-20. (PMID: 26770622)
J Am Coll Surg. 1998 Aug;187(2):171-7. (PMID: 9704964)
J Surg Oncol. 2001 Jul;77(3):171-8. (PMID: 11455553)
Turk J Med Sci. 2021 Sep 8;51(6):2994-3000. (PMID: 34493033)
Arch Gynecol Obstet. 2006 Aug;274(5):316-8. (PMID: 16622685)
AJR Am J Roentgenol. 2013 Aug;201(2):448-55. (PMID: 23883228)
J Am Coll Surg. 2008 Feb;206(2):316-21. (PMID: 18222386)
Cancer. 1970 Sep;26(3):680-5. (PMID: 4318756)
Curr Treat Options Oncol. 2004 Apr;5(2):153-60. (PMID: 14990209)
Invest Radiol. 2005 Jun;40(6):363-7. (PMID: 15905723)
JAMA Dermatol. 2018 Mar 1;154(3):335. (PMID: 29541783)
Cancer. 2002 Jul 1;95(1):1-7. (PMID: 12115309)
Cancer. 2003 May 1;97(9):2142-9. (PMID: 12712465)
J Comput Assist Tomogr. 2006 Jan-Feb;30(1):148-50. (PMID: 16365591)
J Radiol. 2007 Apr;88(4):579-84. (PMID: 17464257)
Breast Cancer Res Treat. 2008 Sep;111(2):313-9. (PMID: 17952590)
Clin Radiol. 1997 Nov;52(11):854-61. (PMID: 9392464)
Br J Radiol. 2004 Dec;77(924):1036-9. (PMID: 15569646)
Cancers (Basel). 2022 May 13;14(10):. (PMID: 35626023)
Cancer Manag Res. 2022 Jan 18;14:237-247. (PMID: 35125891)
Breast Dis. 2020;39(3-4):119-126. (PMID: 32390594)
فهرسة مساهمة: Keywords: Breast neoplasms; local recurrence; pathology; radiology; survival
تواريخ الأحداث: Date Created: 20231013 Latest Revision: 20231031
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10565753
DOI: 10.14744/nci.2023.77010
PMID: 37829736
قاعدة البيانات: MEDLINE
الوصف
تدمد:2536-4553
DOI:10.14744/nci.2023.77010