دورية أكاديمية
أعرض في EDS

Self-Retained, Sutureless Amniotic Membrane Transplantation for the Management of Ocular Surface Diseases.

التفاصيل البيبلوغرافية
العنوان: Self-Retained, Sutureless Amniotic Membrane Transplantation for the Management of Ocular Surface Diseases.
المؤلفون: Chiu HI; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 112, Taiwan., Tsai CC; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 112, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
المصدر: Journal of clinical medicine [J Clin Med] 2023 Sep 27; Vol. 12 (19). Date of Electronic Publication: 2023 Sep 27.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101606588 Publication Model: Electronic Cited Medium: Print ISSN: 2077-0383 (Print) Linking ISSN: 20770383 NLM ISO Abbreviation: J Clin Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2012]-
مستخلص: Amniotic membrane (AM) has anti-inflammation, anti-fibrotic, and regenerative effects. Sutureless cryopreserved AM transplantation, ProKera ® (Bio-Tissue, Inc., Miami, FL, USA), is easily applied by ophthalmologists in the treatment of ocular surface diseases. This retrospective study included patients with ocular surface diseases who received ProKera ® between January 2022 and May 2023. Six patients (9 eyes) with a mean age of 56.8 ± 20.8 years old (range 25-74) and a mean follow-up period of 7.8 ± 4.1 months (range 1-12) were included, including 2 of recurrent conjunctival tumors with limbal and corneal involvement (cases 1-2), 1 of pterygium with marked astigmatism (case 3) and 3 of Stevens-Johnson syndrome (SJS, cases 4-6). ProKera ® was inserted after the lesion excision and deep keratectomy in cases 1-3, and no recurrence or corneal complication was noted. Cases 4-5 were discharged from the intensive care unit and presented with severe chronic SJS. Most ocular manifestations improved significantly after symblepharon release and ProKera ® insertion, except for corneal conjunctivalization in 1 eye (case 5). Case 6 involved early ProKera ® use at the bedside during acute SJS, resulting in complete resolution. We concluded that the adjunctive application of ProKera ® can be effective for ocular surface reconstruction and provides options to intervene earlier for outpatients or patients unstable for invasive surgical intervention.
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معلومات مُعتمدة: V112-C-054 Taipei Veterans General Hospital
فهرسة مساهمة: Keywords: ProKera®; amniotic membrane transplantation; cornea surface disease; cryopreserved; non-ophthalmologist
تواريخ الأحداث: Date Created: 20231014 Latest Revision: 20231031
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10573988
DOI: 10.3390/jcm12196222
PMID: 37834866
قاعدة البيانات: MEDLINE
الوصف
تدمد:2077-0383
DOI:10.3390/jcm12196222