دورية أكاديمية
أعرض في EDS

ELIXIR and Toxicology: a community in development.

التفاصيل البيبلوغرافية
العنوان: ELIXIR and Toxicology: a community in development.
المؤلفون: Martens M; Department of Bioinformatics - BiGCaT, Maastricht University, Maastricht, 6229 ER, The Netherlands., Stierum R; Risk Analysis for Products In Development (RAPID), Netherlands Organisation for applied scientific research TNO, Utrecht, 3584 CB, The Netherlands., Schymanski EL; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Belvaux, 4367, Luxembourg., Evelo CT; Department of Bioinformatics - BiGCaT, Maastricht University, Maastricht, 6229 ER, The Netherlands.; Maastricht Centre for Systems Biology (MaCSBio), Maastricht University, Maastricht, 6229 EN, The Netherlands., Aalizadeh R; Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, 15771, Greece., Aladjov H; Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, 1113, Bulgaria., Arturi K; Department Environmental Chemistry, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, 8600, Switzerland., Audouze K; Université de Paris, Paris, F-75006, France., Babica P; RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic., Berka K; Department of Physical Chemistry, Palacky University Olomouc, Olomouc, 77146, Czech Republic., Bessems J; Unit Health, VITO, Mol, 2400, Belgium., Blaha L; RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic., Bolton EE; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA., Cases M; Chemotargets SL, Barcelona, 08028, Spain., Damalas DΕ; Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, 15771, Greece., Dave K; School of Science, GSFC University, Gujarat, 391750, India., Dilger M; Forschungs- und Beratungsinstitut Gefahrstoffe (FoBiG) GmbH, Freiburg im Breisgau, 79106, Germany., Exner T; Seven Past Nine, Cerknica, 1380, Slovenia., Geerke DP; AIMMS Division of Molecular Toxicology, Vrije Universiteit, Amsterdam, 1081 HZ, The Netherlands., Grafström R; Department of Toxicology, Misvik Biology, Turku, 20520, Finland.; Institute of Environmental Medicine, Karolinska Institute, Stockholm, 17177, Sweden., Gray A; Department of Computer Science, Heriot-Watt University, Edinburgh, UK., Hancock JM; ELIXIR Hub, Wellcome Genome Campus, Cambridge, CB10 1SD, UK., Hollert H; Department Evolutionary Ecology & Environmental Toxicology (E3T), Goethe-University, Frankfurt, D-60438, Germany., Jeliazkova N; Ideaconsult Ltd., Sofia, Bulgaria., Jennen D; Department of Toxicogenomics, Maastricht University, Maastricht, 6200 MD, The Netherlands., Jourdan F; MetaboHUB, French metabolomics infrastructure in Metabolomics and Fluxomics, Toulouse, France.; Toxalim (Research Centre in Food Toxicology), Université de Toulouse, Toulouse, France., Kahlem P; Scientific Network Management SL, Barcelona, 08015, Spain., Klanova J; RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic., Kleinjans J; Department of Toxicogenomics, Maastricht University, Maastricht, 6200 MD, The Netherlands., Kondic T; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Belvaux, 4367, Luxembourg., Kone B; Faculty of Pharmacy, Malaria Research and Training Center, Bamako, BP:1805, Mali., Lynch I; School of Geography, Earth and Environmental Sciences, University of Birmingham, UK, Birmingham, B15 2TT, UK., Maran U; Institute of Chemistry, University of Tartu, Tartu, 50411, Estonia., Martinez Cuesta S; Data Sciences and Quantitative Biology, Discovery Sciences, AstraZeneca, Cambridge, UK., Ménager H; Institut Français de Bioinformatique, Evry, F-91000, France.; Bioinformatics and Biostatistics Hub, Institut Pasteur, Paris, F-75015, France., Neumann S; Research group Bioinformatics and Scientific Data, Leibniz Institute of Plant Biochemistry, Halle, 06120, Germany., Nymark P; Institute of Environmental Medicine, Karolinska Institute, Stockholm, 17177, Sweden., Oberacher H; Institute of Legal Medicine and Core Facility Metabolomics, Medical University of Innsbruck, Innsbruck, A-6020, Austria., Ramirez N; Institut d'Investigacio Sanitaria Pere Virgili-Universitat Rovira i Virgili, Tarragona, 43007, Spain., Remy S; Unit Health, VITO, Mol, 2400, Belgium., Rocca-Serra P; Data Readiness Group, Department of Engineering Science, University of Oxford, Oxford, UK., Salek RM; International Agency for Research on Cancer, World Health Organisation, Lyon, 69372, France., Sallach B; Department of Environment and Geography, University of York, UK, York, YO10 5NG, UK., Sansone SA; Data Readiness Group, Department of Engineering Science, University of Oxford, Oxford, UK., Sanz F; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), Department of Experimental and Health Sciences, Pompeu Fabra University, Barcelona, 08003, Spain., Sarimveis H; National Technical University of Athens, Athens, 15780, Greece., Sarntivijai S; ELIXIR Hub, Wellcome Genome Campus, Cambridge, CB10 1SD, UK., Schulze T; Helmholtz Centre for Environmental Research - UFZ, Leipzig, 04318, Germany., Slobodnik J; Environmental Institute, Koš, 97241, Slovakia., Spjuth O; Department of Pharmaceutical Biosciences and Science for Life Laboratory, Uppsala University, Uppsala, SE-75124, Sweden., Tedds J; ELIXIR Hub, Wellcome Genome Campus, Cambridge, CB10 1SD, UK., Thomaidis N; Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Athens, 15771, Greece., Weber RJM; School of Biosciences, University of Birmingham, UK, Birmingham, B15 2TT, UK., van Westen GJP; Division of Drug Discovery and Safety, Leiden Academic Center for Drug Research, Leiden, 2333 CC, The Netherlands., Wheelock CE; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm SE-141-86, Sweden.; Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, 17177, Sweden., Williams AJ; Center for Computational Toxicology and Exposure, United States Environmental Protection Agency, Research Triangle Park, NC 27711, USA., Witters H; Unit Health, VITO, Mol, 2400, Belgium., Zdrazil B; Department of Pharmaceutical Sciences, University of Vienna, Vienna, 1090, Austria., Županič A; Department Biotechnology and Systems Biology, National Institute of Biology, Ljubljana, 1000, Slovenia., Willighagen EL; Department of Bioinformatics - BiGCaT, Maastricht University, Maastricht, 6229 ER, The Netherlands.
المصدر: F1000Research [F1000Res] 2023 Oct 03; Vol. 10. Date of Electronic Publication: 2023 Oct 03 (Print Publication: 2021).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: F1000 Research Ltd Country of Publication: England NLM ID: 101594320 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-1402 (Electronic) Linking ISSN: 20461402 NLM ISO Abbreviation: F1000Res Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : F1000 Research Ltd
مواضيع طبية MeSH: Biological Science Disciplines*, Europe ; Risk Assessment
مستخلص: Toxicology has been an active research field for many decades, with academic, industrial and government involvement. Modern omics and computational approaches are changing the field, from merely disease-specific observational models into target-specific predictive models. Traditionally, toxicology has strong links with other fields such as biology, chemistry, pharmacology and medicine. With the rise of synthetic and new engineered materials, alongside ongoing prioritisation needs in chemical risk assessment for existing chemicals, early predictive evaluations are becoming of utmost importance to both scientific and regulatory purposes. ELIXIR is an intergovernmental organisation that brings together life science resources from across Europe. To coordinate the linkage of various life science efforts around modern predictive toxicology, the establishment of a new ELIXIR Community is seen as instrumental. In the past few years, joint efforts, building on incidental overlap, have been piloted in the context of ELIXIR. For example, the EU-ToxRisk, diXa, HeCaToS, transQST, and the nanotoxicology community have worked with the ELIXIR TeSS, Bioschemas, and Compute Platforms and activities. In 2018, a core group of interested parties wrote a proposal, outlining a sketch of what this new ELIXIR Toxicology Community would look like. A recent workshop (held September 30th to October 1st, 2020) extended this into an ELIXIR Toxicology roadmap and a shortlist of limited investment-high gain collaborations to give body to this new community. This Whitepaper outlines the results of these efforts and defines our vision of the ELIXIR Toxicology Community and how it complements other ELIXIR activities.
Competing Interests: No competing interests were disclosed.
(Copyright: © 2023 Martens M et al.)
References: Nucleic Acids Res. 2019 Jan 8;47(D1):D1102-D1109. (PMID: 30371825)
Toxicol Sci. 2018 Mar 1;162(1):264-275. (PMID: 29149350)
Mol Inform. 2013 Jan;32(1):47-63. (PMID: 27481023)
ALTEX. 2015;32(1):9-24. (PMID: 25372315)
Environ Int. 2017 Feb;99:97-106. (PMID: 27939949)
Environ Sci Technol. 2020 Mar 3;54(5):2575-2584. (PMID: 31968937)
Nat Rev Drug Discov. 2017 Dec;16(12):811-812. (PMID: 29026211)
Arch Toxicol. 2014 Dec;88(12):2323-32. (PMID: 25326818)
Nat Genet. 2012 Jan 27;44(2):121-6. (PMID: 22281772)
Chem Res Toxicol. 2016 Aug 15;29(8):1225-51. (PMID: 27367298)
Nucleic Acids Res. 2015 Jan;43(Database issue):D921-7. (PMID: 25313160)
Genome Biol. 2019 Aug 12;20(1):164. (PMID: 31405382)
Int J Mol Sci. 2014 Nov 14;15(11):21136-54. (PMID: 25405742)
Genes Nutr. 2018 Apr 30;13:12. (PMID: 29736190)
Beilstein J Nanotechnol. 2015 Jul 27;6:1609-34. (PMID: 26425413)
Regul Toxicol Pharmacol. 2013 Oct;67(1):1-12. (PMID: 23764304)
Science. 2020 Jan 24;367(6476):388-392. (PMID: 31974244)
Environ Sci Technol. 2014 Nov 4;48(21):12760-7. (PMID: 25343693)
Nucleic Acids Res. 2021 Jan 8;49(D1):D1502-D1506. (PMID: 33211879)
Biochimie. 2018 Sep;152:155-158. (PMID: 29960033)
J Cheminform. 2021 Jul 7;13(1):50. (PMID: 34229711)
Nucleic Acids Res. 2018 Jul 2;46(W1):W537-W544. (PMID: 29790989)
F1000Res. 2018 Jun 14;7:. (PMID: 31543945)
J Cheminform. 2011 May 16;3:18. (PMID: 21575202)
Nucleic Acids Res. 2019 Jan 8;47(D1):D711-D715. (PMID: 30357387)
Bioinformatics. 2013 May 15;29(10):1325-32. (PMID: 23479348)
Chem Res Toxicol. 2014 Mar 17;27(3):314-29. (PMID: 24446777)
J Cheminform. 2017 Nov 28;9(1):61. (PMID: 29185060)
Sci Data. 2016 Mar 15;3:160018. (PMID: 26978244)
Nat Commun. 2017 Jul 03;8:15932. (PMID: 28671182)
Nanomaterials (Basel). 2020 Oct 20;10(10):. (PMID: 33092028)
ALTEX. 2016;33(2):95-109. (PMID: 26863090)
J Biomed Semantics. 2015 Mar 21;6:10. (PMID: 25815161)
Curr Opin Pharmacol. 2014 Dec;19:105-11. (PMID: 25244397)
Int J Hyg Environ Health. 2017 Mar;220(2 Pt A):94-97. (PMID: 28284775)
J Chem Inf Model. 2022 Oct 24;62(20):4888-4905. (PMID: 36215146)
F1000Res. 2017 Sep 6;6:. (PMID: 29043062)
Nucleic Acids Res. 2019 Jan 8;47(D1):D1172-D1178. (PMID: 30407529)
Mol Inform. 2010 Jul 12;29(6-7):476-88. (PMID: 27463326)
Environ Sci Technol. 2019 Jan 15;53(2):719-732. (PMID: 30516957)
Cancer Epidemiol Biomarkers Prev. 2005 Aug;14(8):1847-50. (PMID: 16103423)
Trends Biotechnol. 2012 May;30(5):241-2. (PMID: 22417641)
Nat Biotechnol. 2019 Apr;37(4):358-367. (PMID: 30940948)
Environ Sci Eur. 2018;30(1):5. (PMID: 29568720)
Bioinformatics. 2015 May 1;31(9):1505-7. (PMID: 25505093)
Arch Toxicol. 2017 Nov;91(11):3477-3505. (PMID: 29051992)
Bioinformatics. 2020 May 1;36(10):3290-3291. (PMID: 32044952)
Arch Toxicol. 2016 May;90(5):1021-4. (PMID: 27017488)
Drug Discov Today. 2012 Nov;17(21-22):1188-98. (PMID: 22683805)
Science. 2020 Jan 24;367(6476):392-396. (PMID: 31974245)
J Cheminform. 2014 May 14;6:25. (PMID: 24910716)
Int J Mol Sci. 2020 Apr 23;21(8):. (PMID: 32340264)
Chem Res Toxicol. 2020 Jan 21;33(1):7-9. (PMID: 31909603)
Interdiscip Toxicol. 2009 Jun;2(2):42-4. (PMID: 21217844)
Pharmaceuticals (Basel). 2021 Mar 08;14(3):. (PMID: 33800393)
Pharmacogenomics. 2006 Oct;7(7):1025-44. (PMID: 17054413)
NanoImpact. 2018 Jan;9:85-101. (PMID: 30246165)
معلومات مُعتمدة: United Kingdom WT_ Wellcome Trust; 001 International WHO_ World Health Organization
فهرسة مساهمة: Keywords: ELIXIR; FAIR; Toxicology; interoperability
تواريخ الأحداث: Date Created: 20231016 Date Completed: 20231023 Latest Revision: 20240324
رمز التحديث: 20240324
مُعرف محوري في PubMed: PMC10568213
DOI: 10.12688/f1000research.74502.2
PMID: 37842337
قاعدة البيانات: MEDLINE
الوصف
تدمد:2046-1402
DOI:10.12688/f1000research.74502.2