دورية أكاديمية
Treatment Initiation, Substance Use Trajectories, and the Social Determinants of Health in Persons Living With HIV Seeking Medication for Opioid Use Disorder.
العنوان: | Treatment Initiation, Substance Use Trajectories, and the Social Determinants of Health in Persons Living With HIV Seeking Medication for Opioid Use Disorder. |
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المؤلفون: | Cook RR; Department of Medicine, Section of Addiction Medicine, Oregon Health and Science University, Portland, OR, USA., Jaworski EN; Center for Dissemination and Implementation Science, Department of Medicine, University of Illinois-Chicago, Chicago, IL, USA., Hoffman KA; Oregon Health and Science University-Portland State University School of Public Health, Portland, OR, USA., Waddell EN; Oregon Health and Science University-Portland State University School of Public Health, Portland, OR, USA., Myers R; Department of Medicine, Section of Addiction Medicine, Oregon Health and Science University, Portland, OR, USA., Korthuis PT; Department of Medicine, Section of Addiction Medicine, Oregon Health and Science University, Portland, OR, USA., Vergara-Rodriguez P; Ruth M. Rothstein CORE Center - Cook County Health, Chicago, IL, USA. |
المصدر: | Substance abuse [Subst Abus] 2023 Oct; Vol. 44 (4), pp. 301-312. Date of Electronic Publication: 2023 Oct 16. |
نوع المنشور: | Journal Article; Randomized Controlled Trial |
اللغة: | English |
بيانات الدورية: | Publisher: SAGE Publications Country of Publication: United States NLM ID: 8808537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1547-0164 (Electronic) Linking ISSN: 08897077 NLM ISO Abbreviation: Subst Abus Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2023 : [Thousand Oaks] : SAGE Publications Original Publication: Providence, RI : Center for Alcohol and Addiction Studies, Brown University, |
مواضيع طبية MeSH: | Buprenorphine*/therapeutic use , HIV Infections*/drug therapy , Opioid-Related Disorders*/drug therapy, Female ; Humans ; Male ; Middle Aged ; Analgesics, Opioid/therapeutic use ; Opiate Substitution Treatment ; Social Determinants of Health |
مستخلص: | Background: People living with HIV and opioid use disorder (OUD) are disproportionally affected by adverse socio-structural exposures negatively affecting health, which have shown inconsistent associations with uptake of medications for OUD (MOUD). This study aimed to determine whether social determinants of health (SDOH) were associated with MOUD uptake and trajectories of substance use in a clinical trial of people seeking treatment. Methods: Data are from a 2018 to 2019 randomized trial comparing the effectiveness of different MOUD to achieve viral suppression among people living with HIV and OUD. SDOH were defined by variables mapping to Healthy People 2030 domains: education (Education Access and Quality), income (Economic Stability), homelessness (Neighborhood and Built Environment), criminal justice involvement (Social and Community Context), and recent SUD care (Health Care Access and Quality). Associations between SDOH and MOUD initiation were assessed with Cox proportional hazards models, and SDOH and substance use over time with generalized estimating equation models. Results: Participants (N = 114) averaged 47 years old, 63% were male, 56% were Black, and 12% Hispanic. Participants reported an average of 2.3 out of 5 positive SDOH indicators (SD = 1.2). Stable housing was the most commonly reported SDOH (61%), followed by no recent criminal justice involvement (59%), having a high-school level education or greater (56%), income stability (45%), and recent SUD care (13%). Each additional favorable SDOH was associated with a 25% increase in the likelihood of MOUD initiation during the study period [adjusted HR = 1.25, 95% CI = (1.01, 1.55), P = .044]. Positive SDOH were also associated with a decrease in the odds of baseline opioid use and a greater reduction in opioid use during subsequent weeks of the study ( P < .001 for a joint test of baseline and slope differences). Conclusions: Positive social determinants of health, in aggregate, may increase the likelihood of MOUD treatment initiation among people living with HIV and OUD. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
References: | J Clin Med. 2019 Oct 24;8(11):. (PMID: 31652928) AIDS. 2022 Nov 1;36(13):1749-1759. (PMID: 35730392) Addiction. 2012 May;107(5):973-82. (PMID: 22151478) Curr HIV/AIDS Rep. 2019 Feb;16(1):1-6. (PMID: 30684117) JAMA Netw Open. 2022 Mar 1;5(3):e223821. (PMID: 35319762) J Gen Intern Med. 2021 Apr;36(4):930-937. (PMID: 33569735) J Gen Intern Med. 2021 Dec;36(12):3810-3819. (PMID: 34159545) Cureus. 2020 Nov 3;12(11):e11311. (PMID: 33282587) JAMA Netw Open. 2021 Sep 1;4(9):e2123019. (PMID: 34505888) Curr Opin HIV AIDS. 2020 Jul;15(4):250-255. (PMID: 32487818) Addict Sci Clin Pract. 2021 Oct 11;16(1):62. (PMID: 34635170) Addiction. 2016 Jul;111(7):1226-34. (PMID: 26825855) J Addict Med. 2020 Sep/Oct;14(5):415-422. (PMID: 31868830) Drug Alcohol Depend. 2019 May 1;198:70-75. (PMID: 30878769) Curr HIV/AIDS Rep. 2018 Apr;15(2):96-112. (PMID: 29460225) Addict Sci Clin Pract. 2019 Dec 2;14(1):45. (PMID: 31787108) N Engl J Med. 2021 Jan 14;384(2):140-153. (PMID: 33497547) Drug Alcohol Depend. 2021 Aug 1;225:108750. (PMID: 34052690) Drug Alcohol Depend. 2022 Mar 1;232:109337. (PMID: 35123364) J Subst Abuse Treat. 2022 Jul;138:108752. (PMID: 35277306) Drug Alcohol Depend. 2017 Dec 1;181:58-62. (PMID: 29035705) AIDS Behav. 2022 Mar;26(3):975-985. (PMID: 34495424) J Subst Abuse Treat. 2019 Apr;99:32-43. (PMID: 30797392) Contemp Clin Trials Commun. 2019 Jan 07;14:100319. (PMID: 30656242) Addiction. 2020 Aug;115(8):1482-1493. (PMID: 31899565) Clin Infect Dis. 2013 Nov;57(9):1309-17. (PMID: 23797288) Am J Drug Alcohol Abuse. 2019;45(1):1-10. (PMID: 30675818) Harm Reduct J. 2022 Oct 28;19(1):120. (PMID: 36307817) Ann Intern Med. 2020 Jan 21;172(2 Suppl):S50-S59. (PMID: 31958803) Pharmacy (Basel). 2020 Sep 11;8(3):. (PMID: 32932786) Lancet. 2018 Jan 27;391(10118):309-318. (PMID: 29150198) Addiction. 2019 Jul;114(7):1214-1224. (PMID: 30698902) Exp Clin Psychopharmacol. 2012 Jun;20(3):243-50. (PMID: 22329556) Trop Med Infect Dis. 2022 Sep 23;7(10):. (PMID: 36288000) Am J Public Health. 2020 Feb;110(2):244-250. (PMID: 31855487) J Addict Med. 2022 Jan-Feb 01;16(1):93-100. (PMID: 33560695) Am J Addict. 2017 Oct;26(7):667-672. (PMID: 28324627) AIDS Care. 2015;27(3):307-14. (PMID: 25314042) Subst Abus. 2020;41(1):110-120. (PMID: 31403914) J Soc Work Pract Addict. 2014 Jan;14(1):84-100. (PMID: 24634609) J Acquir Immune Defic Syndr. 2020 Nov 1;85(3):272-279. (PMID: 32740370) J Am Board Fam Med. 2019 Sep-Oct;32(5):724-731. (PMID: 31506368) BMC Public Health. 2022 May 4;22(1):886. (PMID: 35508988) BMC Health Serv Res. 2019 Nov 25;19(1):884. (PMID: 31767011) PLoS Med. 2018 Dec 26;15(12):e1002715. (PMID: 30586362) Curr HIV/AIDS Rep. 2022 Feb;19(1):101-112. (PMID: 35107810) AIDS Behav. 2021 Jul;25(7):2230-2239. (PMID: 33449236) Lancet. 2021 Mar 20;397(10279):1139-1150. (PMID: 33617769) Addiction. 2022 Jul;117(7):1961-1971. (PMID: 35129242) Am J Public Health. 2022 Apr;112(S2):S109-S111. (PMID: 35349328) Open Forum Infect Dis. 2021 Jun 22;8(7):ofab330. (PMID: 34307729) Am J Addict. 2020 Mar;29(2):151-154. (PMID: 31951083) Ann Intern Med. 2010 Jun 1;152(11):704-11. (PMID: 20513828) AIDS Behav. 2019 Sep;23(9):2315-2325. (PMID: 30879212) Int J Equity Health. 2019 Feb 19;18(1):36. (PMID: 30782161) Drug Alcohol Depend. 2021 Jul 1;224:108717. (PMID: 33985863) PLoS One. 2017 May 11;12(5):e0177306. (PMID: 28493934) Drug Alcohol Depend. 2019 Jan 1;194:438-446. (PMID: 30502545) J Gen Intern Med. 2023 Sep;38(12):2816-2818. (PMID: 37002460) |
معلومات مُعتمدة: | K01 DA055130 United States DA NIDA NIH HHS; U01 DA047982 United States DA NIDA NIH HHS; UG1 DA015815 United States DA NIDA NIH HHS; UG1 DA015831 United States DA NIDA NIH HHS |
فهرسة مساهمة: | Keywords: HIV; medication for opioid use disorder; opioid use disorder; social determinants of health; substance use disorder |
المشرفين على المادة: | 0 (Analgesics, Opioid) 40D3SCR4GZ (Buprenorphine) |
تواريخ الأحداث: | Date Created: 20231016 Date Completed: 20231104 Latest Revision: 20240202 |
رمز التحديث: | 20240202 |
مُعرف محوري في PubMed: | PMC10830143 |
DOI: | 10.1177/08897077231200745 |
PMID: | 37842910 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1547-0164 |
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DOI: | 10.1177/08897077231200745 |