دورية أكاديمية

Platelet-rich fibrin improves the osteoneogenesis in non-critical defects in calvaria: a histological and histometric study.

التفاصيل البيبلوغرافية
العنوان: Platelet-rich fibrin improves the osteoneogenesis in non-critical defects in calvaria: a histological and histometric study.
المؤلفون: Oliveira ES; Faculdade Evangélica do Paraná - Program in Principles of Surgery - Intituto de Pesquisas Médicas - Curitiba (Paraná) - Brazil., Ribas-Filho JM; Faculdade Evangélica do Paraná - Program in Principles of Surgery - Intituto de Pesquisas Médicas - Curitiba (Paraná) - Brazil., Sigwalt M; Faculdade Evangélica do Paraná - Program in Principles of Surgery - Intituto de Pesquisas Médicas - Curitiba (Paraná) - Brazil., Lourenço ES; Universidade Presbiteriana Mackenzie - São Paulo (São Paulo) - Brazil., Figueiredo FP; Universidade Presbiteriana Mackenzie - São Paulo (São Paulo) - Brazil., Czeczko NG; Faculdade Evangélica do Paraná - Program in Principles of Surgery - Intituto de Pesquisas Médicas - Curitiba (Paraná) - Brazil., Giovanini AF; Faculdade Evangélica do Paraná - Program in Principles of Surgery - Intituto de Pesquisas Médicas - Curitiba (Paraná) - Brazil.
المصدر: Acta cirurgica brasileira [Acta Cir Bras] 2023 Oct 13; Vol. 38, pp. e383423. Date of Electronic Publication: 2023 Oct 13 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina Country of Publication: Brazil NLM ID: 9103983 Publication Model: eCollection Cited Medium: Internet ISSN: 1678-2674 (Electronic) Linking ISSN: 01028650 NLM ISO Abbreviation: Acta Cir Bras Subsets: MEDLINE
أسماء مطبوعة: Publication: Sao Paulo : Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina
Original Publication: São Paulo : A Sociedade,
مواضيع طبية MeSH: Platelet-Rich Fibrin*, Animals ; Rabbits ; Skull/surgery ; Osteogenesis ; Bone Regeneration ; Transplantation, Autologous
مستخلص: Purpose: The aim of this study was to evaluate the effect of platelet-rich fibrin (PRF) and autograft on non-critical bone repair.
Methods: Four bone defects (8.3 × 2 mm) were produced on the calvarium of 15 rabbits. The surgical defects were treated with either autograft, autograft associated to PRF, PRF alone, and sham. Animals were euthanized on the second, fourth or sixth posteoperative week. Histological analyses for presence of bone development on deffect was evaluated comparing the groups treated with autograft and without the autograft separately within the same period. Mann-Whitney's tests were used to compare the percentage of bone repair in each post-operative period for autograft × autograft + PRF groups and also for control × PRF groups (α = 5%).
Results: No differences were observed between the groups that received autograft and autograft associated to PRF on the second and fourth postoperative week, but areas treated with PRF demonstrated significant osteogenesis when compared to sham group on the fourth and sixth weeks. The groups that received PRF (with autograft or alone) demonstrated an enlarged bone deposition when compared to their control group.
Conclusions: The use of PRF may influence bone repair and improve the bone deposition in late period of repair demonstrating osteoconductive and osteogenic properties.
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تواريخ الأحداث: Date Created: 20231018 Date Completed: 20231023 Latest Revision: 20231023
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10578093
DOI: 10.1590/acb383423
PMID: 37851781
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-2674
DOI:10.1590/acb383423